Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1ENW
DownloadVisualize
BU of 1enw by Molmil
ELONGATION FACTOR TFIIS DOMAIN II
分子名称: TRANSCRIPTION ELONGATION FACTOR S-II
著者Morin, P.E, Awrey, D.E, Edwards, A.M, Arrowsmith, C.H.
登録日2000-03-21
公開日2000-04-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Elongation factor TFIIS contains three structural domains: solution structure of domain II.
Proc.Natl.Acad.Sci.USA, 93, 1996
283D
DownloadVisualize
BU of 283d by Molmil
A CURVED RNA HELIX INCORPORATING AN INTERNAL LOOP WITH G-A AND A-A NON-WATSON-CRICK BASE PAIRING
分子名称: MANGANESE (II) ION, RNA (5'-R(*GP*GP*CP*CP*GP*AP*AP*AP*GP*GP*CP*C)-3')
著者Baeyens, K.J, De Bondt, H.L, Pardi, A, Holbrook, S.R.
登録日1996-09-03
公開日1996-09-30
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A curved RNA helix incorporating an internal loop with G.A and A.A non-Watson-Crick base pairing.
Proc.Natl.Acad.Sci.USA, 93, 1996
4EDT
DownloadVisualize
BU of 4edt by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ppGpp and Manganese
分子名称: BENZAMIDINE, DNA primase, GUANOSINE-5',3'-TETRAPHOSPHATE, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDR
DownloadVisualize
BU of 4edr by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to UTP and Manganese
分子名称: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
7E15
DownloadVisualize
BU of 7e15 by Molmil
Protein ternary complex working for DNA replication initiation
分子名称: DNA polymerase II small subunit, Gins51, SsDNA-specific exonuclease
著者Oyama, T, Ishino, Y.
登録日2021-01-30
公開日2021-10-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Family D DNA polymerase interacts with GINS to promote CMG-helicase in the archaeal replisome.
Nucleic Acids Res., 50, 2022
4EDV
DownloadVisualize
BU of 4edv by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese
分子名称: BENZAMIDINE, DNA primase, MANGANESE (II) ION, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDG
DownloadVisualize
BU of 4edg by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to ATP and Manganese
分子名称: ADENOSINE-5'-TRIPHOSPHATE, BENZAMIDINE, DNA primase, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EE1
DownloadVisualize
BU of 4ee1 by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to CTP and Manganese
分子名称: BENZAMIDINE, CYTIDINE-5'-TRIPHOSPHATE, DNA primase, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-28
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4EDK
DownloadVisualize
BU of 4edk by Molmil
The structure of the S. aureus DnaG RNA Polymerase Domain bound to GTP and Manganese
分子名称: BENZAMIDINE, DNA primase, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Rymer, R.U, Solorio, F.A, Chu, C, Corn, J.E, Wang, J.D, Berger, J.M.
登録日2012-03-27
公開日2012-07-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding Mechanism of Metal-NTP Substrates and Stringent-Response Alarmones to Bacterial DnaG-Type Primases.
Structure, 20, 2012
4CGV
DownloadVisualize
BU of 4cgv by Molmil
First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD
分子名称: GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3
著者Roe, S.M, Pal, M.
登録日2013-11-26
公開日2014-05-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
4CGW
DownloadVisualize
BU of 4cgw by Molmil
Second TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD
分子名称: HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3
著者Roe, S.M, Pal, M.
登録日2013-11-26
公開日2014-05-14
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
3HYF
DownloadVisualize
BU of 3hyf by Molmil
Crystal structure of HIV-1 RNase H p15 with engineered E. coli loop and active site inhibitor
分子名称: 2-(3,4-dichlorobenzyl)-5,6-dihydroxypyrimidine-4-carboxylic acid, ACETATE ION, GLYCEROL, ...
著者Lansdon, E.B, Kirschberg, T.A.
登録日2009-06-22
公開日2009-10-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献RNase H active site inhibitors of human immunodeficiency virus type 1 reverse transcriptase: design, biochemical activity, and structural information.
J.Med.Chem., 52, 2009
1XJR
DownloadVisualize
BU of 1xjr by Molmil
The Structure of a Rigorously Conserved RNA Element Within the SARS Virus Genome
分子名称: MAGNESIUM ION, s2m RNA
著者Robertson, M.P, Igel, H, Baertsch, R, Haussler, D, Ares Jr, M, Scott, W.G.
登録日2004-09-24
公開日2005-02-01
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of a rigorously conserved RNA element within the SARS virus genome
Plos Biol., 3, 2005
5BKH
DownloadVisualize
BU of 5bkh by Molmil
The splicing activity and an alternative domain-swapped structure of the Pyrococcus horikoshii PolII mini-intein
分子名称: DNA polymerase II large subunit
著者Li, Z, Li, H.
登録日2021-03-19
公開日2021-08-11
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献An alternative domain-swapped structure of the Pyrococcus horikoshii PolII mini-intein.
Sci Rep, 11, 2021
5FLX
DownloadVisualize
BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
著者Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
登録日2015-10-28
公開日2015-12-23
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
1DYW
DownloadVisualize
BU of 1dyw by Molmil
Biochemical and structural characterization of a divergent loop cyclophilin from Caenorhabditis elegans
分子名称: CYCLOPHILIN 3
著者Dornan, J, Page, A.P, Taylor, P, Wu, S.Y, Winter, A.D, Husi, H, Walkinshaw, M.D.
登録日2000-02-10
公開日2000-06-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Biochemical and Structural Characterization of a Divergent Loop Cyclophilin from Caenorhabditis Elegans
J.Biol.Chem., 274, 1999
7OM6
DownloadVisualize
BU of 7om6 by Molmil
Thosea asigna virus RdRP domain in complex with RNA
分子名称: DI(HYDROXYETHYL)ETHER, RNA (5'-R(P*AP*AP*AP*UP*UP*U)-3'), RNA-dependent RNA polymerase
著者Ferrero, D.S, Falqui, M, Verdaguer, N.
登録日2021-05-21
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Snapshots of a Non-Canonical RdRP in Action.
Viruses, 13, 2021
4S20
DownloadVisualize
BU of 4s20 by Molmil
Structural basis for transcription reactivation by RapA
分子名称: 5'-D(P*AP*CP*GP*AP*CP*TP*GP*AP*GP*CP*CP*GP*AP*TP*G)-3', 5'-R(P*AP*UP*CP*GP*GP*CP*UP*CP*A)-3', DNA-directed RNA polymerase subunit alpha, ...
著者Liu, B, Zuo, Y, Steitz, T.A.
登録日2015-01-16
公開日2015-02-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4.7 Å)
主引用文献Structural basis for transcription reactivation by RapA.
Proc.Natl.Acad.Sci.USA, 112, 2015
8XI2
DownloadVisualize
BU of 8xi2 by Molmil
Cryo-EM structure of the Chlamydomonas C* complex
分子名称: CWF21 domain-containing protein, Cdc5L, Crooked neck protein, ...
著者Lu, Y, Zhan, X.
登録日2023-12-19
公開日2024-10-09
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structure of a step II catalytically activated spliceosome from Chlamydomonas reinhardtii.
Embo J., 2024
6N4O
DownloadVisualize
BU of 6n4o by Molmil
Human Argonaute2-miR-122 bound to a seed and supplementary paired target
分子名称: Protein argonaute-2, RNA (5'-R(*CP*CP*AP*UP*UP*GP*UP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*AP*GP*UP*GP*UP*GP*AP*CP*AP*AP*UP*GP*GP*UP*GP*UP*UP*U)-3')
著者Sheu-Gruttadauria, J, MacRae, I.J.
登録日2018-11-19
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.899 Å)
主引用文献Beyond the seed: structural basis for supplementary microRNA targeting by human Argonaute2.
Embo J., 38, 2019
8G6R
DownloadVisualize
BU of 8g6r by Molmil
Porcine epidemic diarrhea virus core polymerase complex
分子名称: RNA (5'-R(P*AP*AP*GP*AP*AP*GP*CP*UP*AP*UP*UP*AP*AP*AP*AP*UP*CP*AP*CP*A)-3'), RNA (5'-R(P*GP*GP*UP*UP*GP*UP*GP*AP*UP*UP*UP*UP*AP*AP*UP*AP*GP*CP*UP*U)-3'), ZINC ION, ...
著者Anderson, T.K, Kirchdoerfer, R.N.
登録日2023-02-15
公開日2023-03-29
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
7Q2J
DownloadVisualize
BU of 7q2j by Molmil
Quaternary Complex of human WDR5 and pVHL:ElonginC:ElonginB bound to PROTAC Homer
分子名称: Elongin-B, Elongin-C, N-[5-[4-[[5-[[(2S)-3,3-dimethyl-1-[(2S,4R)-2-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]-4-oxidanyl-pyrrolidin-1-yl]-1-oxidanylidene-butan-2-yl]amino]-5-oxidanylidene-pentyl]carbamoyl]phenyl]-2-(4-methylpiperazin-1-yl)phenyl]-6-oxidanylidene-4-(trifluoromethyl)-1H-pyridine-3-carboxamide, ...
著者Kraemer, A, Doelle, A, Schwalm, M.P, Adhikari, B, Wolf, E, Knapp, S, Structural Genomics Consortium (SGC)
登録日2021-10-25
公開日2021-11-24
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization.
Cell Chem Biol, 30, 2023
5ZYQ
DownloadVisualize
BU of 5zyq by Molmil
The Structure of Human PAF1/CTR9 complex
分子名称: RNA polymerase-associated protein CTR9 homolog,RNA polymerase II-associated factor 1 homolog
著者Xie, Y, Zheng, M, Zhou, H, Long, J.
登録日2018-05-28
公開日2018-09-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.531 Å)
主引用文献Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation.
Nat Commun, 9, 2018
8URB
DownloadVisualize
BU of 8urb by Molmil
Porcine epidemic diarrhea virus complete core polymerase complex
分子名称: RNA (33-MER), RNA (55-MER), ZINC ION, ...
著者Anderson, T.K, Kirchdoerfer, R.N.
登録日2023-10-25
公開日2023-11-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An alphacoronavirus polymerase structure reveals conserved co-factor functions.
Biorxiv, 2023
3ISD
DownloadVisualize
BU of 3isd by Molmil
Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ...
著者Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H.
登録日2009-08-25
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".
J.Biol.Chem., 284, 2009

227344

件を2024-11-13に公開中

PDB statisticsPDBj update infoContact PDBjnumon