PDB: 37084 件ウェブページステータス検索Chemie searchBIRD

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3FE0	X-ray crystal structure of wild type human lysozyme in D2O 分子名称: Lysozyme C 著者 Chiba-Kamoshida, K, Matsui, T, Chatake, T, Ohhara, T, Ostermann, A, Tanaka, I, Yutani, K, Niimura, N. 登録日 2008-11-27 公開日 2009-12-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Site-specific softening of peptide bonds by localized deuterium observed by neutron crystallography of human lysozyme hydrogen To be Published
3ZL7	BACE2 FYNOMER COMPLEX 分子名称: BETA-SECRETASE 2, FYNOMER 2B-H11 著者 Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. 登録日 2013-01-28 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
3FGZ	Crystal Structure of CheY triple mutant F14E, N59M, E89R complexed with BeF3- and Mn2+ 分子名称: AMMONIUM ION, BERYLLIUM TRIFLUORIDE ION, Chemotaxis protein cheY, ... 著者 Wollish, A.C, Miller, P.J, Pazy, Y, Collins, E.J, Bourret, R.B. 登録日 2008-12-08 公開日 2009-09-22 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Matching Biochemical Reaction Kinetics to the Timescales of Life: Structural Determinants That Influence the Autodephosphorylation Rate of Response Regulator Proteins. J.Mol.Biol., 392, 2009
4KS2	Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid 分子名称: (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase 著者 Kerry, P.S, Russell, R.J.M. 登録日 2013-05-17 公開日 2013-10-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.595 Å) 主引用文献 Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
3FHP	A neutron crystallographic analysis of a porcine 2Zn insulin at 2.0 A resolution 分子名称: Insulin, ZINC ION 著者 Iwai, W, Kurihara, K, Yamada, T, Kobayashi, Y, Ohnishi, Y, Tanaka, I, Takahashi, H, Niimura, N. 登録日 2008-12-09 公開日 2009-10-20 最終更新日 2023-11-01 実験手法 NEUTRON DIFFRACTION (2 Å) 主引用文献 A neutron crystallographic analysis of T6 porcine insulin at 2.1 A resolution Acta Crystallogr.,Sect.D, 65, 2009
4GCC	Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 1 分子名称: Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C 著者 Helliwell, J.R, Tanley, S.W.M. 登録日 2012-07-30 公開日 2013-01-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation. Acta Crystallogr.,Sect.D, 69, 2013
3FA9	Crystal structure of the apo R132K:Y134F:R111L:L121D mutant of cellular retinoic acid-binding protein II at 1.94 angstrom resolution 分子名称: ACETATE ION, Cellular retinoic acid-binding protein 2 著者 Jia, X, Geiger, J.H. 登録日 2008-11-16 公開日 2009-10-27 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Crystal structures of apo cellular retinoic acid-binding protein II mutants: Structural integrity investigated through multiple site mutations To be Published
4GDJ	A subtype N10 neuraminidase-like protein of A/little yellow-shouldered bat/Guatemala/060/2010 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Neuraminidase, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-07-31 公開日 2012-09-26 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of two subtype N10 neuraminidase-like proteins from bat influenza A viruses reveal a diverged putative active site. Proc.Natl.Acad.Sci.USA, 109, 2012
3DXB	Structure of the UHM domain of Puf60 fused to thioredoxin 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) 著者 Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. 登録日 2008-07-24 公開日 2008-10-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60. J.Biol.Chem., 284, 2009
4K1J	Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding 分子名称: (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Wu, Y, Gao, F, Qi, J.X, Gao, G.F. 登録日 2013-04-05 公開日 2013-06-05 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding Sci Rep, 3, 2013
3ZK5	PikC D50N mutant bound to the 10-DML analog with the 3-(N,N-dimethylamino)ethanoate anchoring group 分子名称: (3R,4S,5S,7R,9E,11R,12R)-12-ethyl-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl N,N-dimethylglycinate, CYTOCHROME P450 HYDROXYLASE PIKC, PROTOPORPHYRIN IX CONTAINING FE 著者 Podust, L.M. 登録日 2013-01-21 公開日 2014-01-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Directing Group-Controlled Regioselectivity in an Enzymatic C-H Bond Oxygenation. J.Am.Chem.Soc., 136, 2014
4GCF	Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 4 分子名称: DIMETHYL SULFOXIDE, Lysozyme C, PLATINUM (II) ION 著者 Helliwell, J.R, Tanley, S.W.M. 登録日 2012-07-30 公開日 2013-01-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation. Acta Crystallogr.,Sect.D, 69, 2013
3E0N	The X-ray structure of Human Prostasin in complex with DFFR-chloromethyl ketone inhibitor 分子名称: DPN-PHE-ARM, GLYCEROL, Prostasin heavy chain, ... 著者 Spraggon, G, Hornsby, M, Shipway, A, Harris, J.L, Lesley, S.A. 登録日 2008-07-31 公開日 2009-06-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations. Protein Sci., 18, 2009
4GJA	Crystal structure of renin in complex with NVP-AYL747 (compound 5) 分子名称: (3S,5R)-N-(2,2-diphenylethyl)-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
4GJC	Crystal structure of renin in complex with NVP-BCH965 (compound 9) 分子名称: (3S,5R)-5-{[(4-methylphenyl)sulfonyl]amino}-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
4K9H	Bace-1 inhibitor complex 分子名称: 1-cyclopentyl-N-[(2S,3R)-3-hydroxy-1-phenyl-4-{[3-(trifluoromethyl)benzyl]amino}butan-2-yl]-6-oxo-5-(2-oxopyrrolidin-1-yl)-1,6-dihydropyridine-3-carboxamide, Beta-secretase 1 著者 Jordan, S.R. 登録日 2013-04-19 公開日 2013-07-10 最終更新日 2013-07-17 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Hydroxyethylamine-based inhibitors of BACE1: P1-P3 macrocyclization can improve potency, selectivity, and cell activity. Bioorg.Med.Chem.Lett., 23, 2013
4GJX	Crystal structure of CD23 lectin domain mutant D258A 分子名称: GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor 著者 Yuan, D, Sutton, B.J, Dhaliwal, B. 登録日 2012-08-10 公開日 2013-06-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288, 2013
4K9W	Complex of human CYP3A4 with a desoxyritonavir analog 分子名称: Cytochrome P450 3A4, N~2~-(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)-N-[(2R,5S)-1-phenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}octan-2-yl]-L-valinamide, PROTOPORPHYRIN IX CONTAINING FE 著者 Sevrioukova, I.F, Poulos, T.L. 登録日 2013-04-21 公開日 2013-06-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Dissecting Cytochrome P450 3A4-Ligand Interactions Using Ritonavir Analogues. Biochemistry, 52, 2013
4KB5	Crystal structure of MycP1 from Mycobacterium smegmatis 分子名称: GLYCEROL, Membrane-anchored mycosin mycp1 著者 Sun, D.M, He, Y, Tian, C.L. 登録日 2013-04-23 公開日 2014-02-05 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability. Protein Cell, 4, 2013
3DK1	Wild Type HIV-1 Protease with potent Antiviral inhibitor GRL-0105A 分子名称: (4aR,6r,7aS)-hexahydro-4aH-cyclopenta[b][1,4]dioxin-6-yl [(1S,2R)-1-benzyl-2-hydroxy-3-{[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino}propyl]carbamate, CHLORIDE ION, Protease, ... 著者 Wang, Y.F, Weber, I.T. 登録日 2008-06-24 公開日 2009-05-12 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.07 Å) 主引用文献 Potent HIV-1 protease inhibitors incorporating meso-bicyclic urethanes as P2-ligands: structure-based design, synthesis, biological evaluation and protein-ligand X-ray studies Org.Biomol.Chem., 6, 2008
4KND	Thioredoxin from Anaeromyxobacter dehalogenans. 分子名称: Thioredoxin 著者 Osipiuk, J, Hatzos-Skintges, C, Clancy, S, Adkins, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) 登録日 2013-05-09 公開日 2013-05-22 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Thioredoxin from Anaeromyxobacter dehalogenans. To be Published
4GI3	Crystal structure of Greglin in complex with subtilisin 分子名称: Greglin, KerA 著者 Kellenberger, C, Roussel, A. 登録日 2012-08-08 公開日 2012-11-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin Febs J., 279, 2012
3DLW	Antichymotrypsin 分子名称: Alpha-1-antichymotrypsin 著者 Feil, S.C. 登録日 2008-06-29 公開日 2009-07-07 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Identification and characterization of a misfolded monomeric serpin formed at physiological temperature J.Mol.Biol., 403, 2010
4GJ9	Crystal structure of renin in complex with GP055321 (compound 4) 分子名称: (2R)-1-(3,8-dihydrodibenzo[b,f]pyrrolo[3,4-d]azepin-2(1H)-yl)propan-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin 著者 Ostermann, N, Zink, F, Kroemer, M. 登録日 2012-08-09 公開日 2013-02-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
3DSJ	Crystal Structure of Arabidopsis thaliana Allene Oxide Synthase Variant (F137L) (At-AOS(F137L), cytochrome P450 74A, CYP74A) Complexed with 13(S)-HOD at 1.60 A Resolution 分子名称: (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, Cytochrome P450 74A, chloroplast, ... 著者 Lee, D.S, Nioche, P, Raman, C.S. 登録日 2008-07-12 公開日 2008-08-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insights into the evolutionary paths of oxylipin biosynthetic enzymes Nature, 455, 2008

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