3ZL7

BACE2 FYNOMER COMPLEX

Summary for 3ZL7

Entry DOI	10.2210/pdb3zl7/pdb
Related	3ZKG 3ZKI 3ZKM 3ZKN 3ZKQ 3ZKS
Descriptor	BETA-SECRETASE 2, FYNOMER 2B-H11 (3 entities in total)
Functional Keywords	hydrolase, aspartyl protease
Biological source	HOMO SAPIENS More
Cellular location	Membrane; Single-pass type I membrane protein: Q9Y5Z0
Total number of polymer chains	2
Total formula weight	52372.80
Authors	Banner, D.W.,Kuglstatter, A.,Benz, J.,Stihle, M.,Ruf, A. (deposition date: 2013-01-28, release date: 2013-05-29, Last modification date: 2023-12-20)
Primary citation	Banner, D.W.,Gsell, B.,Benz, J.,Bertschinger, J.,Burger, D.,Brack, S.,Cuppuleri, S.,Debulpaep, M.,Gast, A.,Grabulovski, D.,Hennig, M.,Hilpert, H.,Huber, W.,Kuglstatter, A.,Kusznir, E.,Laeremans, T.,Matile, H.,Miscenic, C.,Rufer, A.,Schlatter, D.,Steyeart, J.,Stihle, M.,Thoma, R.,Weber, M.,Ruf, A. Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69:1124-, 2013 Cited by PubMed: 23695257 DOI: 10.1107/S0907444913006574 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation