3ZKN

BACE2 FAB INHIBITOR COMPLEX

Summary for 3ZKN

Entry DOI	10.2210/pdb3zkn/pdb
Related	3ZKG 3ZKI 3ZKM 3ZKQ 3ZKX 3ZL7 3ZOV
Descriptor	BETA-SECRETASE 2, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... (8 entities in total)
Functional Keywords	immune system-hydrolase complex, fab complex, immune system/hydrolase
Biological source	HOMO SAPIENS More
Total number of polymer chains	6
Total formula weight	181190.37
Authors	Banner, D.W.,Kuglstatter, A.,Benz, J.,Stihle, M.,Ruf, A. (deposition date: 2013-01-23, release date: 2013-05-29, Last modification date: 2023-12-20)
Primary citation	Banner, D.W.,Gsell, B.,Benz, J.,Bertschinger, J.,Burger, D.,Brack, S.,Cuppuleri, S.,Debulpaep, M.,Gast, A.,Grabulovski, D.,Hennig, M.,Hilpert, H.,Huber, W.,Kuglstatter, A.,Kusznir, E.,Laeremans, T.,Matile, H.,Miscenic, C.,Rufer, A.,Schlatter, D.,Steyeart, J.,Stihle, M.,Thoma, R.,Weber, M.,Ruf, A. Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69:1124-, 2013 Cited by PubMed: 23695257 DOI: 10.1107/S0907444913006574 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation