Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0016020 | cellular_component | membrane |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE WZV A 1398 |
Chain | Residue |
A | ASP48 |
A | TYR87 |
A | GLN89 |
A | ASN123 |
A | LEU126 |
A | ILE134 |
A | ASP241 |
A | THR244 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE DMS A 1399 |
Chain | Residue |
A | CYS282 |
A | TRP283 |
A | GLN279 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 1400 |
Chain | Residue |
A | GLU98 |
A | LEU112 |
A | VAL113 |
A | ASN114 |
A | GLU150 |
A | SER155 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1401 |
Chain | Residue |
A | THR88 |
A | ARG248 |
A | SER339 |
A | THR340 |
A | ASN341 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE WZV B 1398 |
Chain | Residue |
B | ASP48 |
B | GLN89 |
B | ASN123 |
B | LEU126 |
B | ILE134 |
B | ASP241 |
B | THR244 |
B | HOH2161 |
site_id | AC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE DMS B 1399 |
Chain | Residue |
B | GLN279 |
B | CYS282 |
B | TRP283 |
B | HOH2125 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 1400 |
Chain | Residue |
B | GLU98 |
B | LEU112 |
B | VAL113 |
B | ASN114 |
B | GLU150 |
B | SER155 |
site_id | AC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 1401 |
Chain | Residue |
B | THR88 |
B | ARG248 |
B | SER339 |
B | THR340 |
B | ASN341 |
site_id | AC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 C 1217 |
Chain | Residue |
C | PRO192 |
C | SER193 |
C | SER195 |
C | LYS212 |
C | HOH2126 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL C 1218 |
Chain | Residue |
C | ARG38 |
C | LYS43 |
C | GLU46 |
C | ALA62 |
C | PHE63 |
C | ARG66 |
C | HOH2025 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 H 1217 |
Chain | Residue |
H | SER193 |
H | SER195 |
H | LYS212 |
H | HOH2121 |
site_id | BC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL H 1218 |
Chain | Residue |
H | ARG38 |
H | LYS43 |
H | GLU46 |
H | ALA62 |
H | PHE63 |
H | ARG66 |
H | HOH2020 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
Chain | Residue | Details |
A | ILE45-VAL56 | |
A | ALA238-LEU249 | |
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
Chain | Residue | Details |
D | TYR196-HIS202 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | ASP48 | |
A | ASP241 | |
B | ASP48 | |
B | ASP241 | |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN108 | |
A | ASN304 | |
B | ASN108 | |
B | ASN304 | |