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3RES
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BU of 3res by Molmil
Crystal structure of E coli Hfq in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, Protein hfq
著者Wang, W.W, Wu, J.H, Shi, Y.Y.
登録日2011-04-05
公開日2011-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperation of Escherichia coli Hfq hexamers in DsrA binding.
Genes Dev., 25, 2011
3PRP
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BU of 3prp by Molmil
Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin
分子名称: Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L
著者Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D.
登録日2010-11-30
公開日2011-01-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.699 Å)
主引用文献Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
3PTO
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BU of 3pto by Molmil
Crystal Structure of an empty Vesicular Stomatitis Virus Nucleocapsid Protein Complex
分子名称: Nucleoprotein, URANYL (VI) ION
著者Luo, M, Green, T.J, Rowse, M.
登録日2010-12-03
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.008 Å)
主引用文献Access to RNA Encapsidated in the Nucleocapsid of Vesicular Stomatitis Virus.
J.Virol., 85, 2011
3PUH
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BU of 3puh by Molmil
Cocaine Esterase, wild-type biologically active dimer
分子名称: Cocaine esterase, GLYCEROL, SULFATE ION
著者Nance, M.R, Tesmer, J.J.G.
登録日2010-12-04
公開日2011-09-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Subunit stabilization and polyethylene glycolation of cocaine esterase improves in vivo residence time.
Mol.Pharmacol., 80, 2011
3PW3
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BU of 3pw3 by Molmil
Crystal structure of a cysteine protease (BDI_2249) from Parabacteroides distasonis ATCC 8503 at 2.23 A resolution
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Aminopeptidase C, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2010-12-07
公開日2010-12-22
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Crystal structure of a cysteine protease (BDI_2249) from Parabacteroides distasonis ATCC 8503 at 2.23 A resolution
To be published
3Q0Y
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BU of 3q0y by Molmil
N-terminal domain of C. reinhardtii SAS-6 homolog Bld12p
分子名称: Centriole protein
著者Kitagawa, D, Vakonakis, I, Olieric, N, Hilbert, M, Keller, D, Olieric, V, Bortfeld, M, Erat, M.C, Flueckiger, I, Goenczy, P, Steinmetz, M.O.
登録日2010-12-16
公開日2011-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of the 9-fold symmetry of centrioles.
Cell(Cambridge,Mass.), 144, 2011
3Q3Z
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BU of 3q3z by Molmil
Structure of a c-di-GMP-II riboswitch from C. acetobutylicum bound to c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), MAGNESIUM ION, c-di-GMP-II riboswitch
著者Smith, K.D, Shanahan, C.A, Moore, E.L, Simon, A.C, Strobel, S.A.
登録日2010-12-22
公開日2011-05-11
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structural basis of differential ligand recognition by two classes of bis-(3'-5')-cyclic dimeric guanosine monophosphate-binding riboswitches.
Proc.Natl.Acad.Sci.USA, 108, 2011
3Q6W
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BU of 3q6w by Molmil
Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor
分子名称: 3-{5-oxo-3-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl}-N-(pyridin-2-ylmethyl)propanamide, Hepatocyte growth factor receptor
著者Soisson, S.M, Rickert, K.W, Patel, S.B, Lumb, K.J.
登録日2011-01-03
公開日2011-01-19
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for selective small molecule kinase inhibition of activated c-Met.
J.Biol.Chem., 286, 2011
3Q9G
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BU of 3q9g by Molmil
VQIVY segment from Alzheimer's tau displayed on 42-membered macrocycle scaffold
分子名称: ACETIC ACID, Cyclic pseudo-peptide VQIV(4BF)(ORN)(HAO)KL(ORN), GLYCEROL
著者Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J.
登録日2011-01-07
公開日2011-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
3Q9J
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BU of 3q9j by Molmil
AIIFL segment derived from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold
分子名称: CHLORIDE ION, Cyclic pseudo-peptide AIIFL(ORN)(HAO)YK(ORN), GLYCEROL, ...
著者Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J.
登録日2011-01-07
公開日2011-06-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics.
J.Am.Chem.Soc., 133, 2011
3QA0
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BU of 3qa0 by Molmil
Crystal structure of the apo-form of human CK2 alpha at pH 6.5
分子名称: 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION
著者Battistutta, R, Ranchio, A, Papinutto, E.
登録日2011-01-10
公開日2012-01-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
3Q6T
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BU of 3q6t by Molmil
Salivary protein from Lutzomyia longipalpis, Ligand free
分子名称: 43.2 kDa salivary protein, CITRIC ACID
著者Andersen, J.F, Xu, X, Chang, B.W, Collin, N, Valenzuela, J.G, Ribeiro, J.M.
登録日2011-01-03
公開日2011-07-27
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structure and function of a "yellow" protein from saliva of the sand fly Lutzomyia longipalpis that confers protective immunity against Leishmania major infection.
J.Biol.Chem., 286, 2011
3Q8C
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BU of 3q8c by Molmil
Crystal structure of Protective Antigen W346F (pH 5.5)
分子名称: CALCIUM ION, Protective antigen
著者Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G.
登録日2011-01-06
公開日2012-02-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2.
Protein Sci., 21, 2012
3Q9O
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BU of 3q9o by Molmil
Full-length Cholix toxin from Vibrio cholerae in complex with NAD
分子名称: GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, exotoxin A
著者Merrill, A.R, Jorgensen, R, Fieldhouse, R.J.
登録日2011-01-09
公開日2012-01-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.793 Å)
主引用文献The 1.8 a cholix toxin crystal structure in complex with NAD+ and evidence for a new kinetic model.
J.Biol.Chem., 287, 2012
3QAV
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BU of 3qav by Molmil
Crystal structure of a glutathione S-transferase from Antarctic clam Laternula elliptica
分子名称: Rho-class glutathione S-transferase
著者Park, A.K, Moon, J.H, Chi, Y.M.
登録日2011-01-12
公開日2012-02-01
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The structure of a shellfish specific GST class glutathione S-transferase from antarctic bivalve Laternula elliptica reveals novel active site architecture.
Proteins, 81, 2013
3QCG
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BU of 3qcg by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid
分子名称: 3-[(3-bromo-4-chlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, ACETIC ACID, Receptor-type tyrosine-protein phosphatase gamma
著者Sheriff, S.
登録日2011-01-16
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCQ
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BU of 3qcq by Molmil
Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 6-(3-Amino-1H-indazol-6-yl)-N4-ethyl-2,4-pyrimidinediamine
分子名称: 3-phosphoinositide-dependent protein kinase 1, 6-(3-amino-2H-indazol-6-yl)-N~4~-ethylpyrimidine-2,4-diamine, GLYCEROL, ...
著者Medina, J.R, Becker, C.J, Blackledge, C.W, Duquenne, C, Feng, Y, Grant, S.W, Heerding, D, Li, W.H, Miller, W.H, Romeril, S.P, Scherzer, D, Shu, A, Bobko, M.A, Chadderton, A.R, Dumble, M, Gradiner, C.M, Gilbert, S, Liu, Q, Rabindran, S.K, Sudakin, V, Xiang, H, Brady, P.G, Campobasso, N, Ward, P, Axten, J.M.
登録日2011-01-17
公開日2011-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献Structure-Based Design of Potent and Selective 3-Phosphoinositide-Dependent Kinase-1 (PDK1) Inhibitors.
J.Med.Chem., 54, 2011
3QBY
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BU of 3qby by Molmil
Crystal structure of the PWWP domain of human Hepatoma-derived growth factor 2
分子名称: H4K20me3 Histone H4 Peptide, Hepatoma-derived growth factor-related protein 2, SULFATE ION, ...
著者Zeng, H, Tempel, W, Amaya, M.F, Adams-Cioaba, M.A, Mackenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2011-01-14
公開日2011-02-09
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Histone Binding Ability Characterizations of Human PWWP Domains.
Plos One, 6, 2011
3QC6
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BU of 3qc6 by Molmil
GspB
分子名称: CALCIUM ION, GLYCEROL, NITROGEN MOLECULE, ...
著者Pyburn, T.M.
登録日2011-01-15
公開日2011-08-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors.
Plos Pathog., 7, 2011
3QCF
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BU of 3qcf by Molmil
Human receptor protein tyrosine phosphatase gamma, domain 1, in complex with 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid via co-crystallization
分子名称: 3-[(3,4-dichlorobenzyl)sulfanyl]thiophene-2-carboxylic acid, Receptor-type tyrosine-protein phosphatase gamma, SULFATE ION
著者Sheriff, S.
登録日2011-01-16
公開日2011-12-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Small molecule receptor protein tyrosine phosphatase [gamma](RPTP[gamma]) ligands that inhibit phosphatase activity via perturbation of the tryptophan-proline-aspartate (WPD) loop
J.Med.Chem., 54, 2011
3QCT
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BU of 3qct by Molmil
Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment
分子名称: LT3015 antibody Fab fragment, heavy chain, light chain, ...
著者Fleming, J.K, Wojciak, J.M, Campbell, M.-A, Huxford, T.
登録日2011-01-17
公開日2011-03-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1493 Å)
主引用文献Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody.
J.Mol.Biol., 408, 2011
3QG1
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BU of 3qg1 by Molmil
Crystal structure of P-loop G239A mutant of subunit A of the A1AO ATP synthase
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETIC ACID, V-type ATP synthase alpha chain
著者Ragunathan, P, Manimekalai, M.S.S, Kumar, A, Jeyakanthan, J, Gruber, G.
登録日2011-01-24
公開日2011-10-05
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Conserved glycine residues in the P-loop of ATP synthases form a doorframe for nucleotide entrance.
J.Mol.Biol., 413, 2011
3QGH
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BU of 3qgh by Molmil
Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
分子名称: N-cyclopropyl-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, PHOSPHATE ION, RNA-directed RNA polymerase
著者Sheriff, S.
登録日2011-01-24
公開日2011-04-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3QGI
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BU of 3qgi by Molmil
Crystal structure of the hepatitis C virus NS5B RNA-dependent RNA polymerase genotype 1a complex with N-[(2S)-butan-2-yl]-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide
分子名称: GLYCEROL, N-[(2S)-butan-2-yl]-6-[(3R)-3-{[4-(trifluoromethoxy)benzyl]carbamoyl}-4-{[4-(trifluoromethoxy)phenyl]sulfonyl}piperazin-1-yl]pyridazine-3-carboxamide, RNA-directed RNA polymerase
著者Sheriff, S.
登録日2011-01-24
公開日2011-04-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Investigation of the mode of binding of a novel series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides to the hepatitis C virus polymerase.
Bioorg.Med.Chem.Lett., 21, 2011
3QH9
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Human Liprin-beta2 Coiled-Coil
分子名称: AMMONIUM ION, GLYCEROL, IODIDE ION, ...
著者Stafford, R.L, Tang, M, Phillips, M.L, Bowie, J.U.
登録日2011-01-25
公開日2011-10-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Crystal structure of the central coiled-coil domain from human liprin-beta2
Biochemistry, 50, 2011

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