6GFE
 
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7M7B
 | | SARS-CoV-2 Spike:Fab 3D11 complex focused refinement | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab 3D11 heavy chain, Antibody Fab 3D11 light chain, ... | | 著者 | Asarnow, D, Cheng, Y. | | 登録日 | 2021-03-27 | | 公開日 | 2021-05-26 | | 最終更新日 | 2021-06-23 | | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | | 主引用文献 | Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Cell, 184, 2021
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1CF8
 | | Convergence of catalytic antibody and terpene cyclase mechanisms: polyene cyclization directed by carbocation-pi interactions | | 分子名称: | 4-{4-[2-(1A,7A-DIMETHYL-4-OXY-OCTAHYDRO-1-OXA-4-AZA-CYCLOPROPA[A]NAPHTHALEN-4-YL) -ACETYLAMINO]-PHENYLCARBAMOYL}-BUTYRIC ACID, CADMIUM ION, PROTEIN (CATALYTIC ANTIBODY 19A4 (HEAVY CHAIN)), ... | | 著者 | Paschall, C.M, Hasserodt, J, Jones, T, Lerner, R.A, Janda, K.D, Christianson, D.W. | | 登録日 | 1999-03-24 | | 公開日 | 1999-07-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Convergence of Catalytic Antibody and Terpene Cyclase Mechanisms: Polyene Cyclization Directed by Carbocation-pi Interactions
Angew.Chem.Int.Ed.Engl., 38, 1999
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6Z3P
 | | Structure of EV71 in complex with a protective antibody 38-3-11A Fab | | 分子名称: | SPHINGOSINE, VP1, VP2, ... | | 著者 | Zhou, D, Fry, E.E, Ren, J, Stuart, D.I. | | 登録日 | 2020-05-21 | | 公開日 | 2020-09-02 | | 最終更新日 | 2020-10-28 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural and functional analysis of protective antibodies targeting the threefold plateau of enterovirus 71.
Nat Commun, 11, 2020
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3MCL
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1BLN
 | | ANTI-P-GLYCOPROTEIN FAB MRK-16 | | 分子名称: | PROTEIN (MONOCLONAL ANTIBODY MRK-16 (HEAVY CHAIN)), PROTEIN (MONOCLONAL ANTIBODY MRK-16 (LIGHT CHAIN)) | | 著者 | Vasudevan, S, Tsuruo, T, Rose, D.R. | | 登録日 | 1998-07-16 | | 公開日 | 1998-10-28 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Mode of binding of anti-P-glycoprotein antibody MRK-16 to its antigen. A crystallographic and molecular modeling study.
J.Biol.Chem., 273, 1998
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3IY7
 | | Variable domains of the computer generated model (WAM) of Fab F fitted into the cryoEM reconstruction of the virus-Fab F complex | | 分子名称: | fragment from neutralizing antibody F (heavy chain), fragment from neutralizing antibody F (light chain) | | 著者 | Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G. | | 登録日 | 2009-04-09 | | 公開日 | 2009-05-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (14 Å) | | 主引用文献 | Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
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3OCH
 | | Chemically Self-assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic | | 分子名称: | (2S,2'S)-5,5'-(nonane-1,9-diyldiimino)bis(2-{[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]amino}-5-oxopentanoic acid) (non-preferred name), CHLORIDE ION, Dihydrofolate reductase, ... | | 著者 | Cody, V. | | 登録日 | 2010-08-10 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Chemically Self-Assembled Antibody Nanorings (CSANs): Design and Characterization of an Anti-CD3 IgM Biomimetic.
J.Am.Chem.Soc., 132, 2010
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6ULC
 | | Structure of full-length, fully glycosylated, non-modified HIV-1 gp160 bound to PG16 Fab at a nominal resolution of 4.6 Angstrom | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Pan, J, Chen, B, Harrison, S.C. | | 登録日 | 2019-10-07 | | 公開日 | 2020-04-29 | | 最終更新日 | 2020-09-09 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Cryo-EM Structure of Full-length HIV-1 Env Bound With the Fab of Antibody PG16.
J.Mol.Biol., 432, 2020
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2UYL
 | | Crystal structure of a monoclonal antibody directed against an antigenic determinant common to Ogawa and Inaba serotypes of Vibrio cholerae O1 | | 分子名称: | MONOCLONAL ANTIBODY F-22-30 | | 著者 | Ahmed, F, Haouz, A, Nato, F, Fournier, J.M, Alzari, P.M. | | 登録日 | 2007-04-10 | | 公開日 | 2008-05-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of a Monoclonal Antibody Directed Against an Antigenic Determinant Common to Ogawa and Inaba Serotypes of Vibrio Cholerae O1.
Proteins, 70, 2008
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1MJJ
 | | HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12 AND A TRANSITION-STATE ANALOG | | 分子名称: | IMMUNOGLOBULIN MS6-12, N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE, SULFATE ION | | 著者 | Ruzheinikov, S.N, Muranova, T.A, Sedelnikova, S.E, Partridge, L.J, Blackburn, G.M, Murray, I.A, Kakinuma, H, Takashi, N, Shimazaki, K, Sun, J, Nishi, Y, Rice, D.W. | | 登録日 | 2002-08-28 | | 公開日 | 2003-09-23 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High-resolution crystal structure of the Fab-fragments of a family of mouse catalytic antibodies with esterase activity
J.Mol.Biol., 332, 2003
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5A8H
 | | cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FAB OF BROADLY NEUTRALIZING ANTIBODY 17B, FAB OF BROADLY NEUTRALIZING ANTIBODY 8ANC195 VARIANT G52K5, ... | | 著者 | Scharf, L, Wang, H, Gao, H, Chen, S, McDowall, A, Bjorkman, P. | | 登録日 | 2015-07-15 | | 公開日 | 2015-08-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (23 Å) | | 主引用文献 | Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.
Cell, 162, 2015
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1F11
 | | F124 FAB FRAGMENT FROM A MONOCLONAL ANTI-PRES2 ANTIBODY | | 分子名称: | F124 IMMUNOGLOBULIN (IGG1 HEAVY CHAIN), F124 IMMUNOGLOBULIN (KAPPA LIGHT CHAIN) | | 著者 | Saul, F.A, Vulliez-Le Normand, B, Passafiume, M, Riottot, M.M, Bentley, G.A. | | 登録日 | 2000-05-18 | | 公開日 | 2000-08-30 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of the Fab fragment from F124, a monoclonal antibody specific for hepatitis B surface antigen.
Acta Crystallogr.,Sect.D, 56, 2000
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3O11
 | | Anti-beta-amyloid antibody c706 fab in space group c2 | | 分子名称: | C706 HEAVY CHAIN variable region, Ig gamma-1 chain C region chimera, C706 LIGHT CHAIN variable region, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L. | | 登録日 | 2010-07-20 | | 公開日 | 2010-09-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | His-tag binding by antibody C706 mimics beta-amyloid recognition.
J.Mol.Recognit., 24, 2011
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3IY6
 | | Variable domains of the computer generated model (WAM) of Fab E fitted into the cryoEM reconstruction of the virus-Fab E complex | | 分子名称: | fragment from neutralizing antibody E (heavy chain), fragment from neutralizing antibody E (light chain) | | 著者 | Hafenstein, S, Bowman, V.D, Sun, T, Nelson, C.D, Palermo, L.M, Chipman, P.R, Battisti, A.J, Parrish, C.R, Rossmann, M.G. | | 登録日 | 2009-04-09 | | 公開日 | 2009-05-12 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Structural comparison of different antibodies interacting with parvovirus capsids
J.Virol., 83, 2009
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3QEH
 | | Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody | | 分子名称: | CHLORIDE ION, Fab fragment of human anti-HIV-1 Env antibody N12-i15, heavy chain, ... | | 著者 | Guan, Y, DeVico, A.L, Lewis, G.K, Pazgier, M. | | 登録日 | 2011-01-20 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody
To be Published
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1UB5
 | | Crystal structure of Antibody 19G2 with hapten at 100K | | 分子名称: | 4-(4-STYRYL-PHENYLCARBAMOYL)-BUTYRIC ACID, antibody 19G2, alpha chain, ... | | 著者 | Beuscher, A.B, Wirsching, P, Lerner, R.A, Janda, K, Stevens, R.C. | | 登録日 | 2003-03-30 | | 公開日 | 2004-04-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and Dynamics of Blue Fluorescent Antibody 19G2 at Blue and Violet Fluorescent Temperatures
To be published
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6IW2
 | | Crystal structure of 5A ScFv in complex with YFV-17D sE in prefusion state | | 分子名称: | Envelope protein E, Heavy chain of monoclonal antibody 5A, Light chain of monoclonal antibody 5A | | 著者 | Lu, X.S, Xiao, H.X, Li, S.H, Pang, X.F. | | 登録日 | 2018-12-04 | | 公開日 | 2019-02-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Double Lock of a Human Neutralizing and Protective Monoclonal Antibody Targeting the Yellow Fever Virus Envelope.
Cell Rep, 26, 2019
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5XRQ
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2PW1
 | | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWNSL | | 分子名称: | 2F5 Fab fragment heavy chain, 2F5 Fab fragment light chain, peptide epitope | | 著者 | Bryson, S, Julien, J.-P, Hynes, R.C, Pai, E.F. | | 登録日 | 2007-05-10 | | 公開日 | 2007-05-22 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications.
J.Virol., 83, 2009
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5MP6
 | | Structure of the Unliganded Fab from HIV-1 Neutralizing Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface, at two Angstrom resolution. | | 分子名称: | CAP248-2B Heavy Chain, CAP248-2B Light Chain, SULFATE ION | | 著者 | Wibmer, C.K, Gorman, J, Kwong, P.D. | | 登録日 | 2016-12-15 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.959 Å) | | 主引用文献 | Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.
PLoS Pathog., 13, 2017
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7R6X
 | | SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Monoclonal antibody S2E12 Fab heavy chain, ... | | 著者 | Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M. | | 登録日 | 2021-06-23 | | 公開日 | 2021-07-21 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
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3DV4
 | | Crystal structure of SAG506-01, tetragonal, crystal 1 | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | | 著者 | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | | 登録日 | 2008-07-18 | | 公開日 | 2008-12-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
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8F60
 | | anti-BTLA monoclonal antibody r23C8 in complex with BTLA | | 分子名称: | ACETATE ION, B- and T-lymphocyte attenuator, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Hendle, J, Atwell, S, Lieu, R, Hickey, M, Weichert, K. | | 登録日 | 2022-11-15 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Epitope topography of agonist antibodies to the checkpoint inhibitory receptor BTLA.
Structure, 31, 2023
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3DUU
 | | Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2 | | 分子名称: | 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid, Ig-like protein, MAGNESIUM ION, ... | | 著者 | Brooks, C.L, Blackler, R.J, Gerstenbruch, S, Kosma, P, Muller-Loennies, S, Brade, H, Evans, S.V. | | 登録日 | 2008-07-17 | | 公開日 | 2008-12-02 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Pseudo-symmetry and twinning in crystals of homologous antibody Fv fragments.
Acta Crystallogr.,Sect.D, 64, 2008
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