8CPB
 
 | | 1,6-anhydro-n-actetylmuramic acid kinase (AnmK) in complex with AMPPNP, and AnhMurNAc at 1.7 Angstroms resolution. | | 分子名称: | 2-(2-ACETYLAMINO-4-HYDROXY-6,8-DIOXA-BICYCLO[3.2.1]OCT-3-YLOXY)-PROPIONIC ACID, Anhydro-N-acetylmuramic acid kinase, GLYCEROL, ... | | 著者 | Jimenez-Faraco, E, Hermoso, J.A. | | 登録日 | 2023-03-02 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Catalytic process of anhydro-N-acetylmuramic acid kinase from Pseudomonas aeruginosa.
J.Biol.Chem., 299, 2023
|
|
5UTO
 | | The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstrom resolution | | 分子名称: | EDD domain protein, DegV family, PALMITIC ACID | | 著者 | Cuypers, M.G, Ericson, M, Subramanian, C, Broussard, T.C, Miller, D.J, White, S.W, Rock, C.O. | | 登録日 | 2017-02-15 | | 公開日 | 2018-02-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
|
|
6NDJ
 | |
8CHJ
 | | Human FKBP12 in complex with (1S,5S,6R)-10-((R)-(3,5-dichlorophenyl)sulfonimidoyl)-3-(pyridin-2-ylmethyl)-5-vinyl-3,10-diazabicyclo[4.3.1]decan-2-one | | 分子名称: | (1S,5S,6R)-10-[[3,5-bis(chloranyl)phenyl]sulfonimidoyl]-5-ethenyl-3-(pyridin-2-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-2-one, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Meyners, C, Purder, P.L, Hausch, F. | | 登録日 | 2023-02-08 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.697 Å) | | 主引用文献 | Deconstructing Protein Binding of Sulfonamides and Sulfonamide Analogues.
Jacs Au, 3, 2023
|
|
6NMM
 | |
7OC8
 | | Trichoderma reesei Cel7A E212Q mutant in complex with pNPL | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, Exoglucanase 1, ... | | 著者 | Haataja, T, Sandgren, M, Stahlberg, J. | | 登録日 | 2021-04-26 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Enzyme kinetics by GH7 cellobiohydrolases on chromogenic substrates is dictated by non-productive binding: insights from crystal structures and MD simulation.
Febs J., 290, 2023
|
|
7W65
 | | Crystal structure of minor pilin TcpB from Vibrio cholerae complexed with secreted protein TcpF | | 分子名称: | Toxin coregulated pilus biosynthesis protein F, Toxin-coregulated pilus biosynthesis protein B | | 著者 | Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S. | | 登録日 | 2021-12-01 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.05 Å) | | 主引用文献 | Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor.
Sci Adv, 8, 2022
|
|
6NN1
 | | Xanthomonas citri PGM Apo-Dephospho | | 分子名称: | DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Stiers, K.M, Beamer, L.J. | | 登録日 | 2019-01-14 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and dynamical description of the enzymatic reaction of a phosphohexomutase.
Struct Dyn., 6, 2019
|
|
5LVT
 | |
8CP9
 | |
7OHN
 | | SaFtsZ complexed with GDP, AlF4- and Mg2+ | | 分子名称: | Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2021-05-11 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
|
|
5FNO
 | | Manganese Lipoxygenase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MANGANESE (II) ION, ... | | 著者 | Wennman, A, Karkehabadi, S, Oliw, E.H, Chen, Y. | | 登録日 | 2015-11-16 | | 公開日 | 2016-01-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.038 Å) | | 主引用文献 | Crystal Structure of Manganese Lipoxygenase of the Rice Blast Fungus Magnaporthe Oryzae
J.Biol.Chem., 291, 2016
|
|
8PEI
 | | Crystal structure of the biphotochromic fluorescent protein SAASoti (C21N/V127T variant) in its green on-state | | 分子名称: | C21N/V127T form of the biphotochromic fluorescent protein SAASoti | | 著者 | Boyko, K.M, Varfolomeeva, L.A, Matyuta, I.O, Gavshina, A.V, Solovyev, I.D, Popov, V.O, Savitsky, A.P. | | 登録日 | 2023-06-14 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-07-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The role of the correlated motion(s) of the chromophore in photoswitching of green and red forms of the photoconvertible fluorescent protein mSAASoti.
Sci Rep, 14, 2024
|
|
7W63
 | | Crystal structure of minor pilin TcpB from Vibrio cholerae | | 分子名称: | SULFATE ION, Toxin-coregulated pilus biosynthesis protein B | | 著者 | Oki, H, Kawahara, K, Iimori, M, Imoto, Y, Maruno, T, Uchiyama, S, Muroga, Y, Yoshida, A, Yoshida, T, Ohkubo, T, Matsuda, S, Iida, T, Nakamura, S. | | 登録日 | 2021-12-01 | | 公開日 | 2022-11-09 | | 最終更新日 | 2022-11-16 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structural basis for the toxin-coregulated pilus-dependent secretion of Vibrio cholerae colonization factor.
Sci Adv, 8, 2022
|
|
5FOB
 | | Crystal Structure of Human Complement C3b in complex with Smallpox Inhibitor of Complement (SPICE) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, COMPLEMENT C3 BETA CHAIN, ... | | 著者 | Forneris, F, Wu, J, Xue, X, Gros, P. | | 登録日 | 2015-11-18 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Regulators of Complement Activity Mediate Inhibitory Mechanisms Through a Common C3B-Binding Mode.
Embo J., 35, 2016
|
|
8C3U
 | | Crystal Structure of human IL-1beta in complex with a low molecular weight antagonist | | 分子名称: | (S)-4'-hydroxy-3'-(6-methyl-2-oxo-3-(1H-pyrazol-4-yl)indolin-3-yl)-[1,1'-biphenyl]-2,4-dicarboxylic acid, Interleukin-1 beta | | 著者 | Rondeau, J.-M, Lehmann, S, Koch, E. | | 登録日 | 2022-12-28 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | | 主引用文献 | Discovery of a selective and biologically active low-molecular weight antagonist of human interleukin-1 beta.
Nat Commun, 14, 2023
|
|
5V2V
 | | Ethylene forming enzyme in complex with nickel | | 分子名称: | 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, NICKEL (II) ION | | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | | 登録日 | 2017-03-06 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
|
|
8PW2
 | |
5LHB
 | | POLYADPRIBOSYL GLYCOSIDASE IN COMPLEX WITH PDD00017262 | | 分子名称: | 1-(cyclopropylmethyl)-6-[[(1-methylcyclopropyl)amino]-bis(oxidanyl)-$l^{4}-sulfanyl]-3-[(2-methyl-1,3-thiazol-5-yl)methyl]quinazoline-2,4-dione, DIMETHYL SULFOXIDE, Poly(ADP-ribose) glycohydrolase, ... | | 著者 | Tucker, J, Barkauskaite, E. | | 登録日 | 2016-07-10 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib.
ACS Chem. Biol., 11, 2016
|
|
5UWF
 | | Crystal structure of human PDE10A in complex with inhibitor 16d | | 分子名称: | 9-[(1S)-2,2-difluorocyclopropane-1-carbonyl]-6-[(4-methoxyphenyl)methyl]-8,9,10,11-tetrahydropyrido[4',3':4,5]thieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one, MAGNESIUM ION, ZINC ION, ... | | 著者 | Xu, R, Cedervall, E.P, Sridhar, V, Barker, R, Aertgeerts, K. | | 登録日 | 2017-02-21 | | 公開日 | 2017-04-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
J. Med. Chem., 60, 2017
|
|
8BJ7
 | |
7OAR
 | | Crystal structure of helicase Pif1 from Thermus oshimai in complex with parallel G-quadruplex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DNA (28-MER), MAGNESIUM ION, ... | | 著者 | Dai, Y.X, Liu, N.N, Guo, H.L, Chen, W.F, Rety, S, Xi, X.G. | | 登録日 | 2021-04-20 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structural mechanism underpinning Thermus oshimai Pif1-mediated G-quadruplex unfolding.
Embo Rep., 23, 2022
|
|
5V2Y
 | | Ethylene forming enzyme in complex with manganese, 2-oxoglutarate and L-arginine | | 分子名称: | 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ARGININE, ... | | 著者 | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | | 登録日 | 2017-03-06 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.428 Å) | | 主引用文献 | Structures and Mechanisms of the Non-Heme Fe(II)- and 2-Oxoglutarate-Dependent Ethylene-Forming Enzyme: Substrate Binding Creates a Twist.
J. Am. Chem. Soc., 139, 2017
|
|
7OHL
 | | SaFtsZ complexed with GDP, BeF3- and Mn2+ | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, Cell division protein FtsZ, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Fernandez-Tornero, C, Ruiz, F.M, Andreu, J.M. | | 登録日 | 2021-05-11 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics.
Plos Biol., 20, 2022
|
|
7NYT
 | | Trichoderma reesei Cel7A E212Q mutant in complex with lactose. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, Exoglucanase 1, ... | | 著者 | Haataja, T, Sandgren, M, Stahlberg, J. | | 登録日 | 2021-03-23 | | 公開日 | 2022-03-09 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Enzyme kinetics by GH7 cellobiohydrolases on chromogenic substrates is dictated by non-productive binding: insights from crystal structures and MD simulation.
Febs J., 290, 2023
|
|
