PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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3NZJ	Crystal structure of yeast 20S proteasome in complex with ligand 2a 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Proteasome component C1, Proteasome component C11, ... 著者 Groll, M, Gallastegui, N, Marechal, X, Le Ravalec, V, Basse, N, Richy, N, Genin, E, Huber, R, Moroder, M, Vidal, V, Reboud-Ravaux, M. 登録日 2010-07-16 公開日 2011-02-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 20S proteasome inhibition: designing noncovalent linear peptide mimics of the natural product TMC-95A. Chemmedchem, 5, 2010
1YHW	Crystal Structure of PAK1 kinase domain with one point mutations (K299R) 分子名称: Serine/threonine-protein kinase PAK 1 著者 Lei, M, Robinson, M.A, Harrison, S.C. 登録日 2005-01-10 公開日 2005-05-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Active Conformation of the PAK1 Kinase Domain Structure, 13, 2005
3K2Z	Crystal structure of a LexA protein from Thermotoga maritima 分子名称: GLYCEROL, LexA repressor 著者 Zhang, A.P.P, Rice, P.A. 登録日 2009-09-30 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Crystal structure of a LexA protein from Thermotoga maritima To be Published
3JAP	Structure of a partial yeast 48S preinitiation complex in closed conformation 分子名称: 18S rRNA, MAGNESIUM ION, METHIONINE, ... 著者 Llacer, J.L, Hussain, T, Ramakrishnan, V. 登録日 2015-06-18 公開日 2015-08-12 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.9 Å) 主引用文献 Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex. Mol.Cell, 59, 2015
4HCY	Structure of a eukaryotic thiaminase-I bound to the thiamin analogue 3-deazathiamin 分子名称: 2-{4-[(4-amino-2-methylpyrimidin-5-yl)methyl]-3-methylthiophen-2-yl}ethanol, thiaminase-I 著者 Kreinbring, C.A, Hubbard, P.A, Leeper, F.J, Hawksley, D, Petsko, G.A, Ringe, D. 登録日 2012-10-01 公開日 2013-10-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure of a eukaryotic thiaminase I. Proc.Natl.Acad.Sci.USA, 111, 2014
4QV9	yCP beta5-C63F mutant 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-14 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QW4	yCP in complex with carfilzomib 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-16 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
3JC5	Structure of the eukaryotic replicative CMG helicase and pumpjack motion 分子名称: Cell division control protein 45, DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, ... 著者 Li, H, Bai, L, Yuan, Z, Sun, J, Georgescu, R.E, Liu, J, O'Donnell, M.E. 登録日 2015-11-24 公開日 2016-02-10 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nat.Struct.Mol.Biol., 23, 2016
4QWU	yCP beta5-C52F mutant in complex with bortezomib 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-17 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
1YKT	Trypsin/Bpti complex mutant 分子名称: CALCIUM ION, Pancreatic trypsin inhibitor, SULFATE ION, ... 著者 Brown, C.K, Ohlendorf, D.H. 登録日 2005-01-18 公開日 2006-04-25 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin J.Mol.Biol., 375, 2008
1YKV	Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene 分子名称: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION 著者 Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. 登録日 2005-01-18 公開日 2005-02-22 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation. Nat.Struct.Mol.Biol., 12, 2005
4QZX	yCP beta5-C63F mutant in complex with the epoxyketone inhibitor ONX 0914 分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-29 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QV8	yCP beta5-C52F mutant 分子名称: CHLORIDE ION, MAGNESIUM ION, Probable proteasome subunit alpha type-7, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-14 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
4QVV	yCP beta5-A49V mutant in complex with bortezomib 分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-16 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
3J6D	Model of the PrgH-PrgK periplasmic rings 分子名称: Pathogenicity 1 island effector protein, Protein PrgH 著者 Bergeron, J.R.C, Strynadka, N.C.J. 登録日 2014-02-14 公開日 2015-01-14 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (11.7 Å) 主引用文献 The Modular Structure of the Inner-Membrane Ring Component PrgK Facilitates Assembly of the Type III Secretion System Basal Body. Structure, 23, 2015
7AWT	E. coli NADH quinone oxidoreductase hydrophilic arm 分子名称: FE2/S2 (INORGANIC) CLUSTER, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... 著者 Schimpf, J, Grishkovskaya, I, Haselbach, D, Friedrich, T. 登録日 2020-11-09 公開日 2021-09-15 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.73 Å) 主引用文献 Structure of the peripheral arm of a minimalistic respiratory complex I. Structure, 30, 2022
4QWS	yCP beta5-C63F mutant in complex with carfilzomib 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-17 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
3J3V	Atomic model of the immature 50S subunit from Bacillus subtilis (state I-a) 分子名称: 50S ribosomal protein L1, 50S ribosomal protein L11, 50S ribosomal protein L13, ... 著者 Li, N, Guo, Q, Zhang, Y, Yuan, Y, Ma, C, Lei, J, Gao, N. 登録日 2013-04-28 公開日 2013-06-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (13.3 Å) 主引用文献 Cryo-EM structures of the late-stage assembly intermediates of the bacterial 50S ribosomal subunit Nucleic Acids Res., 41, 2013
4QZ6	yCP beta5-A49T-A50V double mutant in complex with the epoxyketone inhibitor ONX 0914 分子名称: 1,2,4-trideoxy-4-methyl-2-{[N-(morpholin-4-ylacetyl)-L-alanyl-O-methyl-L-tyrosyl]amino}-1-phenyl-D-xylitol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ... 著者 Huber, E.M, Heinemeyer, W, Groll, M. 登録日 2014-07-27 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Structure, 23, 2015
3J78	Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class I - non-rotated ribosome with 2 tRNAs) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. 登録日 2014-05-29 公開日 2014-08-06 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.3 Å) 主引用文献 Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
4R17	Ligand-induced aziridine-formation at subunit beta5 of the yeast 20S proteasome 分子名称: (2S,3S)-3-methylaziridine-2-carboxylic acid, MAGNESIUM ION, Proteasome subunit alpha type-1, ... 著者 Dubiella, C, Cui, H, Gersch, M, Brouwer, A.J, Sieber, S.A, Krueger, A, Liskamp, R, Groll, M. 登録日 2014-08-04 公開日 2014-10-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site. Angew.Chem.Int.Ed.Engl., 53, 2014
7AMV	Atomic structure of the poxvirus transcription pre-initiation complex in the initially melted state 分子名称: ATP-dependent helicase VETFS, DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, ... 著者 Grimm, C, Bartuli, J, Fischer, U. 登録日 2020-10-09 公開日 2021-10-06 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
7AOF	Atomic structure of the poxvirus transcription late pre-initiation complex 分子名称: DNA-directed RNA polymerase, DNA-directed RNA polymerase 147 kDa polypeptide, DNA-directed RNA polymerase 18 kDa subunit, ... 著者 Grimm, C, Bartuli, J, Fischer, U. 登録日 2020-10-14 公開日 2021-10-06 最終更新日 2021-10-20 実験手法 ELECTRON MICROSCOPY (2.98 Å) 主引用文献 Structural basis of the complete poxvirus transcription initiation process. Nat.Struct.Mol.Biol., 28, 2021
5N4B	Prolyl oligopeptidase B from Galerina marginata bound to 25mer macrocyclization substrate - S577A mutant 分子名称: Alpha-amanitin proprotein, Prolyl oligopeptidase 著者 Czekster, C.M, McMahon, S.A, Ludewig, H, Naismith, J.H. 登録日 2017-02-10 公開日 2017-11-01 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates. Nat Commun, 8, 2017
3NWI	The Soluble Domain Structure of the ZntB Zn2+ Efflux System 分子名称: ZINC ION, Zinc transport protein zntB 著者 Wan, Q, Dealwis, C. 登録日 2010-07-09 公開日 2011-03-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.13 Å) 主引用文献 The Soluble Domain Structure of the ZntB Zn2+ Efflux System TO BE PUBLISHED

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