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6HGJ
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BU of 6hgj by Molmil
Crystal structure of Alpha1-antichymotrypsin variant NewBG-III: a new binding globulin in complex with aldosterone
分子名称: 1,2-ETHANEDIOL, ALDOSTERONE, Alpha-1-antichymotrypsin
著者Schmidt, K, Muller, Y.A.
登録日2018-08-23
公開日2019-05-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.825 Å)
主引用文献NewBG: A surrogate corticosteroid-binding globulin with an unprecedentedly high ligand release efficacy.
J.Struct.Biol., 207, 2019
6HEK
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BU of 6hek by Molmil
Structure of human USP28 bound to Ubiquitin-PA
分子名称: CHLORIDE ION, Polyubiquitin-B, TETRAETHYLENE GLYCOL, ...
著者Gersch, M, Komander, D.
登録日2018-08-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
5X8S
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BU of 5x8s by Molmil
Crystal Structure of the mutant Human ROR gamma Ligand Binding Domain With Ursolic acid.
分子名称: Nuclear receptor ROR-gamma, Ursolic acid
著者Noguchi, M, Nomura, A, Murase, K, Doi, S, Yamaguchi, K, Adachi, T.
登録日2017-03-03
公開日2017-06-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Ternary complex of human ROR gamma ligand-binding domain, inverse agonist and SMRT peptide shows a unique mechanism of corepressor recruitment
Genes Cells, 22, 2017
8J03
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BU of 8j03 by Molmil
Human KCNQ2(F104A)-CaM-PIP2-CBD complex in state I
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 2, cannabidiol
著者Ma, D, Li, D, Guo, J.
登録日2023-04-09
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Ligand activation mechanisms of human KCNQ2 channel.
Nat Commun, 14, 2023
8PD0
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BU of 8pd0 by Molmil
cryo-EM structure of Doa10 in MSP1E3D1
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
著者Botsch, J.J, Braeuning, B, Schulman, B.A.
登録日2023-06-11
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
8PDA
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BU of 8pda by Molmil
cryo-EM structure of Doa10 with RING domain in MSP1E3D1
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, ERAD-associated E3 ubiquitin-protein ligase DOA10
著者Botsch, J.J, Braeuning, B, Schulman, B.A.
登録日2023-06-12
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Doa10/MARCH6 architecture interconnects E3 ligase activity with lipid-binding transmembrane channel to regulate SQLE.
Nat Commun, 15, 2024
5WEO
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BU of 5weo by Molmil
Activated GluA2 complex bound to glutamate, cyclothiazide, and STZ in digitonin
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit chimera
著者Twomey, E.C, Yelshanskaya, M.V, Grassucci, R.A, Frank, J, Sobolevsky, A.I.
登録日2017-07-10
公開日2017-08-02
最終更新日2019-11-20
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Channel opening and gating mechanism in AMPA-subtype glutamate receptors.
Nature, 549, 2017
6HEI
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BU of 6hei by Molmil
Structure of the catalytic domain of USP28 (insertion deleted) bound to Ubiquitin-PA
分子名称: 1,2-ETHANEDIOL, Polyubiquitin-B, Ubiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28
著者Gersch, M, Komander, D.
登録日2018-08-20
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74, 2019
6JXJ
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BU of 6jxj by Molmil
Rb+-bound E2-AlF state of the gastric proton pump (Tyr799Trp)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Abe, K, Irie, K.
登録日2019-04-23
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A single K + -binding site in the crystal structure of the gastric proton pump.
Elife, 8, 2019
6JXH
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BU of 6jxh by Molmil
K+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Abe, K, Irie, K.
登録日2019-04-23
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A single K + -binding site in the crystal structure of the gastric proton pump.
Elife, 8, 2019
6AAO
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BU of 6aao by Molmil
Crystal structure of Methanosarcina mazei PylRS(Y306A/Y384F) complexed with TCO*Lys
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Yanagisawa, T, Kuratani, M, Yokoyama, S.
登録日2018-07-18
公開日2019-04-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.403 Å)
主引用文献Structural Basis for Genetic-Code Expansion with Bulky Lysine Derivatives by an Engineered Pyrrolysyl-tRNA Synthetase.
Cell Chem Biol, 26, 2019
6JXI
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BU of 6jxi by Molmil
Rb+-bound E2-MgF state of the gastric proton pump (Tyr799Trp)
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ...
著者Abe, K, Irie, K.
登録日2019-04-23
公開日2019-08-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A single K + -binding site in the crystal structure of the gastric proton pump.
Elife, 8, 2019
5XA8
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BU of 5xa8 by Molmil
Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E1-ALF4-ADP-2CA2+ crystals
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C.
登録日2017-03-11
公開日2017-05-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Protein-phospholipid interplay revealed with crystals of a calcium pump.
Nature, 545, 2017
5XAA
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BU of 5xaa by Molmil
Complete structure factors and an atomic model of the calcium pump (SERCA1A) and associated phospholipids in the E2-ALF-(TG) crystals of P21212 symmetry
分子名称: 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, ...
著者Norimatsu, Y, Hasegawa, K, Shimizu, N, Toyoshima, C.
登録日2017-03-11
公開日2017-05-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Protein-phospholipid interplay revealed with crystals of a calcium pump.
Nature, 545, 2017
7TE8
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BU of 7te8 by Molmil
CA14-CBD-DB21 ternary complex
分子名称: CA14, DB21, cannabidiol
著者Cao, S, Zheng, N.
登録日2022-01-04
公開日2022-01-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Defining molecular glues with a dual-nanobody cannabidiol sensor.
Nat Commun, 13, 2022
7T37
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BU of 7t37 by Molmil
Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, cannabidiol
著者Pumroy, R.A, Protopopova, A.D, Gallo, P.N, Moiseenkova-Bell, V.Y.
登録日2021-12-07
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into TRPV2 activation by small molecules.
Nat Commun, 13, 2022
7T8S
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BU of 7t8s by Molmil
Light Harvesting complex phycoerythrin PE 566, from the cryptophyte Cryptomonas pyrenoidifera
分子名称: Bilin 584 (doubly linked), Bilin 584 (single linked), Bilin 618 (single linked), ...
著者Michie, K.A, Harrop, S.J, Rathbone, H.W, Wilk, K.E, Curmi, P.M.G.
登録日2021-12-17
公開日2023-02-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular structures reveal the origin of spectral variation in cryptophyte light harvesting antenna proteins.
Protein Sci., 32, 2023
7TNK
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BU of 7tnk by Molmil
Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNO
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BU of 7tno by Molmil
Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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BU of 7tnm by Molmil
Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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BU of 7tnl by Molmil
Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNN
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BU of 7tnn by Molmil
Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
5JP1
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BU of 5jp1 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to tomato SUMO
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, MALONATE ION, Small ubiquitin-related modifier, ...
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
7TNJ
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BU of 7tnj by Molmil
Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNP
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BU of 7tnp by Molmil
Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022

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