8G60
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![BU of 8g60 by Molmil](/molmil-images/mine/8g60) | mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.54 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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8G61
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![BU of 8g61 by Molmil](/molmil-images/mine/8g61) | mRNA decoding in human is kinetically and structurally distinct from bacteria (AC state) | 分子名称: | 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ... | 著者 | Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C. | 登録日 | 2023-02-14 | 公開日 | 2023-04-19 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | mRNA decoding in human is kinetically and structurally distinct from bacteria. Nature, 617, 2023
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7OLC
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![BU of 7olc by Molmil](/molmil-images/mine/7olc) | Thermophilic eukaryotic 80S ribosome at idle POST state | 分子名称: | 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... | 著者 | Kisonaite, M, Wild, K, Sinning, I. | 登録日 | 2021-05-19 | 公開日 | 2022-01-26 | 最終更新日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
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8BTK
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![BU of 8btk by Molmil](/molmil-images/mine/8btk) | Structure of the TRAP complex with the Sec translocon and a translating ribosome | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | 登録日 | 2022-11-29 | 公開日 | 2023-05-24 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Molecular basis of the TRAP complex function in ER protein biogenesis. Nat.Struct.Mol.Biol., 30, 2023
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8BQF
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![BU of 8bqf by Molmil](/molmil-images/mine/8bqf) | Adenylate Kinase L107I MUTANT | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE | 著者 | Scheerer, D, Adkar, B.V, Bhattacharyya, S, Levy, D, Iljina, M, Iljina, I, Dym, O, Haran, G, Shakhnovich, E.I. | 登録日 | 2022-11-21 | 公開日 | 2023-05-10 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase. Proc.Natl.Acad.Sci.USA, 120, 2023
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8RJ4
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![BU of 8rj4 by Molmil](/molmil-images/mine/8rj4) | E. coli adenylate kinase in complex with two ADP molecules and Mg2+ as a result of enzymatic AP4A hydrolysis | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Adenylate kinase, CHLORIDE ION, ... | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | 登録日 | 2023-12-20 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | Magnesium Induced Structural Preorganization in the Active Site of Adenylate Kinase. Sci Adv, 2024
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2AK3
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8RJ6
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![BU of 8rj6 by Molmil](/molmil-images/mine/8rj6) | E. coli adenylate kinase in complex with ATP and AMP and Mg2+ as a result of enzymatic AP4A hydrolysis. | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Tischlik, S, Ronge, P, Wolf-Watz, M, Sauer-Eriksson, A.E. | 登録日 | 2023-12-20 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Magnesium Induced Structural Preorganization in the Active Site of Adenylate Kinase. Sci Adv, 2024
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8JIW
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![BU of 8jiw by Molmil](/molmil-images/mine/8jiw) | Atomic structure of wheat ribosome reveals unique features of the plant ribosomes | 分子名称: | 18S rRNA, 30S ribosomal protein S4, chloroplastic, ... | 著者 | Mishra, R.K, Sharma, P, Hussain, T. | 登録日 | 2023-05-28 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | 主引用文献 | Cryo-EM structure of wheat ribosome reveals unique features of the plant ribosomes. Structure, 32, 2024
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8BHF
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![BU of 8bhf by Molmil](/molmil-images/mine/8bhf) | Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4 | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S11, ... | 著者 | Absmeier, E, Chandrasekaran, V, O'Reilly, F.J, Stowell, J.A.W, Rappsilber, J, Passmore, L.A. | 登録日 | 2022-10-31 | 公開日 | 2023-09-06 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Modulation of GluA2-gamma 5 synaptic complex desensitization, polyamine block and antiepileptic perampanel inhibition by auxiliary subunit cornichon-2. Nat.Struct.Mol.Biol., 30, 2023
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2AK2
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![BU of 2ak2 by Molmil](/molmil-images/mine/2ak2) | ADENYLATE KINASE ISOENZYME-2 | 分子名称: | ADENYLATE KINASE ISOENZYME-2, SULFATE ION | 著者 | Schlauderer, G.J, Schulz, G.E. | 登録日 | 1995-12-29 | 公開日 | 1996-06-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of bovine mitochondrial adenylate kinase: comparison with isoenzymes in other compartments. Protein Sci., 5, 1996
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4TF4
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![BU of 4tf4 by Molmil](/molmil-images/mine/4tf4) | ENDO/EXOCELLULASE:CELLOPENTAOSE FROM THERMOMONOSPORA | 分子名称: | CALCIUM ION, T. FUSCA ENDO/EXO-CELLULASE E4 CATALYTIC DOMAIN AND CELLULOSE-BINDING DOMAIN, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose, ... | 著者 | Sakon, J, Wilson, D.B, Karplus, P.A. | 登録日 | 1997-05-31 | 公開日 | 1997-09-04 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of endo/exocellulase E4 from Thermomonospora fusca. Nat.Struct.Biol., 4, 1997
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7OYB
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![BU of 7oyb by Molmil](/molmil-images/mine/7oyb) | Cryo-EM structure of the 6 hpf zebrafish embryo 80S ribosome | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | 登録日 | 2021-06-24 | 公開日 | 2022-07-13 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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7OYA
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![BU of 7oya by Molmil](/molmil-images/mine/7oya) | Cryo-EM structure of the 1 hpf zebrafish embryo 80S ribosome | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | 登録日 | 2021-06-24 | 公開日 | 2022-07-13 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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8T1D
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![BU of 8t1d by Molmil](/molmil-images/mine/8t1d) | Open-state cryo-EM structure of full-length human TRPV4 in complex with agonist 4a-PDD | 分子名称: | (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera | 著者 | Talyzina, I.A, Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | 登録日 | 2023-06-02 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.35 Å) | 主引用文献 | Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14, 2023
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8T1B
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![BU of 8t1b by Molmil](/molmil-images/mine/8t1b) | Cryo-EM structure of full-length human TRPV4 in apo state | 分子名称: | (2R)-2-{[(4-O-hexopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-4-{[(25R)-5beta,14beta,17beta-spirostan-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, SODIUM ION, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera, ... | 著者 | Nadezhdin, K.D, Talyzina, I.A, Neuberger, A, Sobolevsky, A.I. | 登録日 | 2023-06-02 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14, 2023
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8T1F
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![BU of 8t1f by Molmil](/molmil-images/mine/8t1f) | Cryo-EM structure of full-length human TRPV4 in complex with antagonist HC-067047 | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-methyl-1-[3-(morpholin-4-yl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide, Transient receptor potential cation channel subfamily V member 4/Enhanced green fluorescent protein chimera | 著者 | Talyzina, I.A, Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | 登録日 | 2023-06-02 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14, 2023
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7OYD
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![BU of 7oyd by Molmil](/molmil-images/mine/7oyd) | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | 登録日 | 2021-06-24 | 公開日 | 2022-07-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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8T1C
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![BU of 8t1c by Molmil](/molmil-images/mine/8t1c) | Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA, Transient receptor potential cation channel subfamily V member 4-Enhanced green fluorescent protein chimera | 著者 | Nadezhdin, K.D, Talyzina, I.A, Neuberger, A, Sobolevsky, A.I. | 登録日 | 2023-06-02 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | 主引用文献 | Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14, 2023
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8T1E
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![BU of 8t1e by Molmil](/molmil-images/mine/8t1e) | Closed-state cryo-EM structure of full-length human TRPV4 in the presence of 4a-PDD | 分子名称: | (2R)-2-{[(4-O-hexopyranosyl-beta-D-glucopyranosyl)oxy]methyl}-4-{[(25R)-5beta,14beta,17beta-spirostan-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, SODIUM ION, Transient receptor potential cation channel subfamily V member 4,Enhanced green fluorescent protein, ... | 著者 | Talyzina, I.A, Nadezhdin, K.D, Neuberger, A, Sobolevsky, A.I. | 登録日 | 2023-06-02 | 公開日 | 2023-07-05 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Structure of human TRPV4 in complex with GTPase RhoA. Nat Commun, 14, 2023
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7OYC
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![BU of 7oyc by Molmil](/molmil-images/mine/7oyc) | Cryo-EM structure of the Xenopus egg 80S ribosome | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Leesch, F, Lorenzo-Orts, L, Grishkovskaya, I, Kandolf, S, Belacic, K, Meinhart, A, Haselbach, D, Pauli, A. | 登録日 | 2021-06-24 | 公開日 | 2022-07-20 | 最終更新日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | A molecular network of conserved factors keeps ribosomes dormant in the egg. Nature, 613, 2023
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8G4E
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4U50
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![BU of 4u50 by Molmil](/molmil-images/mine/4u50) | Crystal structure of Verrucarin bound to the yeast 80S ribosome | 分子名称: | (4S,5R,10E,12Z,16R,16aS,17S,18R,19aR,23aR)-4-hydroxy-5,16a,21-trimethyl-4,5,6,7,16,16a,22,23-octahydro-3H,18H,19aH-spiro[16,18-methano[1,6,12]trioxacyclooctadecino[3,4-d]chromene-17,2'-oxirane]-3,9,14-trione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. | 登録日 | 2014-07-24 | 公開日 | 2014-10-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
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8JF7
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8T4S
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