3RME
 
 | | AMCase in complex with Compound 5 | | 分子名称: | Acidic mammalian chitinase, GLYCEROL, N-ethyl-2-(4-methylpiperazin-1-yl)pyridine-3-carboxamide | | 著者 | Olland, A. | | 登録日 | 2011-04-20 | | 公開日 | 2011-08-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Identification and Characterization of Acidic Mammalian Chitinase Inhibitors
J.Med.Chem., 53, 2010
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7RCH
 | | Crystal structure of NS1-ED of Vietnam influenza A virus in complex with the p85-beta-iSH2 domain of human PI3K | | 分子名称: | Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | | 著者 | Kim, I, Zhao, B, Li, P, Cho, J.H. | | 登録日 | 2021-07-07 | | 公開日 | 2022-07-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus.
Nat Commun, 13, 2022
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7RGW
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7R27
 | | Crystal structure of the L. plantarum D-alanine ligase DltA | | 分子名称: | ADENOSINE MONOPHOSPHATE, D-ALANINE, D-alanine--D-alanyl carrier protein ligase | | 著者 | Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C. | | 登録日 | 2022-02-04 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum.
Sci Rep, 12, 2022
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7VZM
 | | Anti-CRISPR AcrIE4-F7 | | 分子名称: | AcrIE4-F7 | | 著者 | Hong, S.H, Lee, G, Bae, E, Suh, J.Y. | | 登録日 | 2021-11-16 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of AcrIE4-F7 reveals a common strategy for dual CRISPR inhibition by targeting PAM recognition sites.
Nucleic Acids Res., 50, 2022
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7R49
 | | Crystal structure of the L. plantarum acyl carrier protein synthase (AcpS)in complex with D-alanyl carrier protein (DltC1) | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4'-PHOSPHOPANTETHEINE, D-alanyl carrier protein 1, ... | | 著者 | Nikolopoulos, N, Ravaud, S, Simorre, J.P, Grangeasse, C. | | 登録日 | 2022-02-08 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | DltC acts as an interaction hub for AcpS, DltA and DltB in the teichoic acid D-alanylation pathway of Lactiplantibacillus plantarum.
Sci Rep, 12, 2022
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3TS0
 | | Mouse Lin28A in complex with let-7f-1 microRNA pre-element | | 分子名称: | Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*GP*UP*AP*GP*UP*GP*AP*UP*UP*UP*UP*AP*CP*CP*CP*UP*GP*GP*AP*G)-3'), ZINC ION | | 著者 | Nam, Y, Sliz, P. | | 登録日 | 2011-09-11 | | 公開日 | 2011-11-16 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.763 Å) | | 主引用文献 | Molecular Basis for Interaction of let-7 MicroRNAs with Lin28.
Cell(Cambridge,Mass.), 147, 2011
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7R56
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7R4S
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3TVL
 | | Complex between the human thiamine triphosphatase and triphosphate | | 分子名称: | 1,2-ETHANEDIOL, TRIPHOSPHATE, Thiamine-triphosphatase | | 著者 | Delvaux, D, Herman, R, Sauvage, E, Wins, P, Bettendorff, L, Charlier, P, Kerff, F. | | 登録日 | 2011-09-20 | | 公開日 | 2012-10-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural determinants of specificity and catalytic mechanism in mammalian 25-kDa thiamine triphosphatase.
Biochim.Biophys.Acta, 1830, 2013
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7YIR
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7YIS
 | | Crystal structure of N-terminal PH domain of ARAP3 protein in complex with inositol 1,3,4,5-tetrakisphosphate | | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 | | 著者 | Zhang, Y.J, Liu, Y.R, Wu, B. | | 登録日 | 2022-07-18 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structural Insights Uncover the Specific Phosphoinositide Recognition by the PH1 Domain of Arap3.
Int J Mol Sci, 24, 2023
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3TYO
 | | Structure of neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-((furan-2-ylmethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3S,4S)-4-{2-[(furan-2-ylmethyl)amino]ethoxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2011-09-26 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.927 Å) | | 主引用文献 | Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.
Bioorg.Med.Chem., 20, 2012
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7WFY
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3SZS
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3T50
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3RM9
 | | AMCase in complex with Compound 3 | | 分子名称: | 4-(4-chlorophenyl)piperazine-1-carboximidamide, Acidic mammalian chitinase | | 著者 | Olland, A. | | 登録日 | 2011-04-20 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Identification and Characterization of Acidic Mammalian Chitinase Inhibitors
J.Med.Chem., 53, 2010
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3R3C
 | | Crystal structure of Arthrobacter sp. strain SU 4-hydroxybenzoyl CoA thioesterase mutant H64A complexed with 4-hydroxyphenacyl CoA | | 分子名称: | 4-HYDROXYPHENACYL COENZYME A, 4-hydroxybenzoyl-CoA thioesterase | | 著者 | Holden, H.M, Thoden, J.B, Song, F, Zhuang, Z, Trujillo, M, Dunaway-Mariano, D. | | 登録日 | 2011-03-15 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The Catalytic Mechanism of the Hotdog-fold Enzyme Superfamily 4-Hydroxybenzoyl-CoA Thioesterase from Arthrobacter sp. Strain SU.
Biochemistry, 51, 2012
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7XV4
 | | Crystal structure of RPA70N-ATRIP fusion | | 分子名称: | ATR-interacting protein, Replication protein A 70 kDa DNA-binding subunit | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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7XV1
 | | Crystal structure of RPA70N-HelB fusion | | 分子名称: | DNA helicase B, Replication protein A 70 kDa DNA-binding subunit | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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7XUT
 | | Crystal structure of RPA70N-WRN fusion | | 分子名称: | fusion protein of Replication protein A 70 kDa DNA-binding subunit and Werner syndrome ATP-dependent helicase | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-19 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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7XV0
 | | Crystal structure of RPA70N-BLMp1 fusion | | 分子名称: | Bloom syndrome protein, Replication protein A 70 kDa DNA-binding subunit | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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3TYM
 | | Structure of neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-((2-methoxybenzyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine | | 分子名称: | 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3S,4S)-4-{2-[(2-methoxybenzyl)amino]ethoxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... | | 著者 | Li, H, Poulos, T.L. | | 登録日 | 2011-09-26 | | 公開日 | 2012-03-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.
Bioorg.Med.Chem., 20, 2012
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7XUV
 | | Crystal structure of RPA70N-RMI1 fusion | | 分子名称: | RecQ-mediated genome instability protein 1, Replication protein A 70 kDa DNA-binding subunit | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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7XUW
 | | Crystal structure of RPA70N-BLMp2 fusion | | 分子名称: | fusion protein of Replication protein A 70 kDa DNA-binding subunit and Bloom syndrome protein | | 著者 | Wu, Y.Y, Zang, N, Fu, W.M, Zhou, C. | | 登録日 | 2022-05-20 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural characterization of human RPA70N association with DNA damage response proteins.
Elife, 12, 2023
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