3RM9
AMCase in complex with Compound 3
Summary for 3RM9
Entry DOI | 10.2210/pdb3rm9/pdb |
Related | 3RM4 3RM8 3RME |
Descriptor | Acidic mammalian chitinase, 4-(4-chlorophenyl)piperazine-1-carboximidamide (3 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Secreted. Isoform 2: Cytoplasm. Isoform 3: Cytoplasm: Q9BZP6 |
Total number of polymer chains | 2 |
Total formula weight | 88884.18 |
Authors | Olland, A. (deposition date: 2011-04-20, release date: 2011-08-24, Last modification date: 2023-09-13) |
Primary citation | Cole, D.C.,Olland, A.M.,Jacob, J.,Brooks, J.,Bursavich, M.G.,Czerwinski, R.,Declercq, C.,Johnson, M.,Joseph-McCarthy, D.,Ellingboe, J.W.,Lin, L.,Nowak, P.,Presman, E.,Strand, J.,Tam, A.,Williams, C.M.M.,Yao, S.,Tsao, D.H.H.,Fitz, L.J. Identification and Characterization of Acidic Mammalian Chitinase Inhibitors J.Med.Chem., 53:6122-6128, 2010 Cited by PubMed: 20666458PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report