PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

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6D0I	ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS. L48M ParT, SeMet-substituted complex. 分子名称: GLYCEROL, ParS: COG5642 (DUF2384) antitoxin fragment, ParT: COG5654 (RES domain) toxin 著者 Piscotta, F.J, Jeffrey, P.D, Link, A.J. 登録日 2018-04-10 公開日 2019-01-09 最終更新日 2019-01-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5XPN	Crystal structure of VDR-LBD complexed with 25RS-(hydroxyphenyl)-25-methoxy-2-methylidene-19,26,27-trinor-1-hydroxyvitamin D3 分子名称: (1~{R},3~{R})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-1-[(2~{R},6~{R})-6-(4-hydroxyphenyl)-6-methoxy-hexan-2-yl]-7~{a}-methyl-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-2-methylidene-cyclohexane-1,3-diol, (1~{R},3~{R})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-1-[(2~{R},6~{S})-6-(4-hydroxyphenyl)-6-methoxy-hexan-2-yl]-7~{a}-methyl-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-2-methylidene-cyclohexane-1,3-diol, Mediator of RNA polymerase II transcription subunit 1, ... 著者 Kato, A, Itoh, T, Yamamoto, K. 登録日 2017-06-03 公開日 2018-07-11 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Vitamin D Analogues with a p-Hydroxyphenyl Group at the C25 Position: Crystal Structure of Vitamin D Receptor Ligand-Binding Domain Complexed with the Ligand Explains the Mechanism Underlying Full Antagonistic Action J. Med. Chem., 60, 2017
3KQ6	Enhancing the Therapeutic Properties of a Protein by a Designed Zinc-Binding Site, Structural principles of a novel long-acting insulin analog 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Wan, Z.L, Hu, S.Q, Whittaker, L, Phillips, N.B, Whittake, J, Ismail-Beigi, F, Weiss, M.A. 登録日 2009-11-17 公開日 2010-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Supramolecular protein engineering: design of zinc-stapled insulin hexamers as a long acting depot. J.Biol.Chem., 285, 2010
5UGH	Crystal structure of Mat2a bound to the allosteric inhibitor PF-02929366 分子名称: 2-(7-chloro-5-phenyl[1,2,4]triazolo[4,3-a]quinolin-1-yl)-N,N-dimethylethan-1-amine, S-adenosylmethionine synthase isoform type-2 著者 Kaiser, S.E, Feng, J, Stewart, A.E. 登録日 2017-01-08 公開日 2017-05-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.062 Å) 主引用文献 Targeting S-adenosylmethionine biosynthesis with a novel allosteric inhibitor of Mat2A. Nat. Chem. Biol., 13, 2017
4NXN	Crystal Structure of the 30S ribosomal subunit from a GidB (RsmG) mutant of Thermus thermophilus (HB8), bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2013-12-09 公開日 2014-05-21 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.544 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
4DR4	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, cognate transfer RNA anticodon stem-loop and multiple copies of paromomycin molecules bound 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.969 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
4DR7	Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with codon, crystallographically disordered near-cognate transfer RNA anticodon stem-loop mismatched at the second codon position, and streptomycin bound 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-16 公開日 2012-11-14 最終更新日 2013-01-30 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
5WHF	Crystal structure of vimentin coil 1B packed in a high-order filamentous form 分子名称: GLYCEROL, Vimentin 著者 Obiero, J.M, Pang, A.H, Tsodikov, O.V. 登録日 2017-07-16 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 A crystal structure of coil 1B of vimentin in the filamentous form provides a model of a high-order assembly of a vimentin filament. FEBS J., 285, 2018
3ZTJ	Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY HEAVY CHAIN, ... 著者 Voss, J.E, Vachieri, S.G, Gamblin, S.J, Collins, P.J, Haire, L.F, Skehel, J.J. 登録日 2011-07-08 公開日 2011-08-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.41 Å) 主引用文献 A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins. Science, 333, 2011
3EOG	Co-crystallization showing exon recognition by a group II intron 分子名称: 5'-R(*UP*UP*AP*UP*UP*A)-3', Group IIC intron, MAGNESIUM ION, ... 著者 Toor, N, Rajashankar, K, Keating, K.S, Pyle, A.M. 登録日 2008-09-26 公開日 2008-10-28 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.391 Å) 主引用文献 Structural basis for exon recognition by a group II intron. Nat.Struct.Mol.Biol., 15, 2008
2WV5	Crystal structure of foot-and-mouth disease virus 3C protease in complex with a decameric peptide corresponding to the VP1-2A cleavage junction with a GLN to Glu substitution at P1 分子名称: FOOT AND MOUTH DISEASE VIRUS (SEROTYPE A) VARIANT VP1 CAPSID PROTEIN, PICORNAIN 3C 著者 Zunszain, P.A, Knox, S.R, Sweeney, T.R, Yang, J, Roque-Rosell, N, Belsham, G.J, Leatherbarrow, R.J, Curry, S. 登録日 2009-10-13 公開日 2009-10-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Insights Into Cleavage Specificity from the Crystal Structure of Foot-and-Mouth Disease Virus 3C Protease Complexed with a Peptide Substrate. J.Mol.Biol., 395, 2010
7YCA	Cryo-EM structure of the PSI-LHCI-Lhcp supercomplex from Ostreococcus tauri 分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaenyl]cyclohex-3-en-1-ol, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... 著者 Shan, J, Sheng, X, Ishii, A, Watanabe, A, Song, C, Murata, K, Minagawa, J, Liu, Z. 登録日 2022-07-01 公開日 2023-04-26 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 The photosystem I supercomplex from a primordial green alga Ostreococcus tauri harbors three light-harvesting complex trimers. Elife, 12, 2023
3HOR	Structure of the actin-binding domain of human filamin A (reduced) 分子名称: Filamin-A, PHOSPHATE ION 著者 Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. 登録日 2009-06-03 公開日 2009-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders Hum.Mol.Genet., 18, 2009
3ZUM	Photosynthetic Reaction Centre Mutant with Phe L146 replaced with Ala 分子名称: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (III) ION, ... 著者 Gibasiewicz, K, Pajzderska, M, Potter, J.A, Fyfe, P.K, Dobek, A, Brettel, K, Jones, M.R. 登録日 2011-07-19 公開日 2011-11-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mechanism of Recombination of the P(+)H(A)(-) Radical Pair in Mutant Rhodobacter Sphaeroides Reaction Centers with Modified Free Energy Gaps between P(+)B(A)(-) and P(+)H(A)(-). J Phys Chem B, 115, 2011
3HOC	Structure of the actin-binding domain of human filamin A mutant E254K 分子名称: Filamin-A, PHOSPHATE ION 著者 Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J. 登録日 2009-06-02 公開日 2009-10-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders Hum.Mol.Genet., 18, 2009
4B7F	Structure of a liganded bacterial catalase 分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Gumiero, A, Walsh, M. 登録日 2012-08-20 公開日 2013-08-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A Structural and Dynamic Investigation of the Inhibition of Catalase by Nitric Oxide. Org.Biomol.Chem., 11, 2013
6CRM	Crystal Structure of RecQ catalytic core from C. sakazakii bound to an unfolded G-quadruplex 分子名称: DNA (5'-D(P*GP*GP*GP*TP*CP*GP*GP*TP*GP*CP*CP*TP*TP*A)-3'), RecQ, ZINC ION 著者 Voter, A.F, Keck, J.L. 登録日 2018-03-19 公開日 2018-10-17 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.19286251 Å) 主引用文献 A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases. Nat Commun, 9, 2018
3IIU	Structure of the reconstituted Peridinin-Chlorophyll a-Protein (RFPCP) mutant N89L 分子名称: (2S)-3-[(6-O-alpha-D-galactopyranosyl-beta-D-galactopyranosyl)oxy]-2-[(3Z,6Z,9Z,12Z,15Z)-octadeca-3,6,9,12,15-pentaenoyloxy]propyl (5Z,8Z,11Z,14Z,17Z)-icosa-5,8,11,14,17-pentaenoate, CADMIUM ION, CHLORIDE ION, ... 著者 Schulte, T, Hofmann, E. 登録日 2009-08-03 公開日 2009-11-24 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Identification of a single peridinin sensing Chl-a excitation in reconstituted PCP by crystallography and spectroscopy. Proc.Natl.Acad.Sci.USA, 106, 2009
6BZU	Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 19B3 分子名称: 19B3 Heavy Chain, 19B3 Light Chain, E2 AS412 peptide 著者 Tzarum, N, Aleman, F, Kong, L, Wilson, I.A, Law, M. 登録日 2017-12-26 公開日 2018-06-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3LN8	The X-ray structure of Zf-RNase-1 from a new crystal form at pH 7.3 分子名称: HYDROLASE, SULFATE ION 著者 Russo Krauss, I, Merlino, A, Mazzarella, L, Sica, F. 登録日 2010-02-02 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish. Biochem.J., 433, 2010
2W2D	Crystal Structure of a Catalytically Active, Non-toxic Endopeptidase Derivative of Clostridium botulinum Toxin A 分子名称: ACETATE ION, BOTULINUM NEUROTOXIN A HEAVY CHAIN, BOTULINUM NEUROTOXIN A LIGHT CHAIN, ... 著者 Masuyer, G, Thiyagarajan, N, James, P.L, Marks, P.M.H, Chaddock, J.A, Acharya, K.R. 登録日 2008-10-29 公開日 2009-03-24 最終更新日 2022-05-04 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal Structure of a Catalytically Active, Non-Toxic Endopeptidase Derivative of Clostridium Botulinum Toxin A. Biochem.Biophys.Res.Commun., 381, 2009
4DV3	Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, C912A, bound with streptomycin 分子名称: 16S rRNA, MAGNESIUM ION, STREPTOMYCIN, ... 著者 Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. 登録日 2012-02-22 公開日 2013-02-27 実験手法 X-RAY DIFFRACTION (3.547 Å) 主引用文献 A structural basis for streptomycin resistance To be Published
2WKQ	Structure of a photoactivatable Rac1 containing the Lov2 C450A Mutant 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... 著者 Wu, Y.I, Frey, D, Lungu, O.I, Jaehrig, A, Schlichting, I, Kuhlman, B, Hahn, K.M. 登録日 2009-06-16 公開日 2009-08-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Genetically Encoded Photoactivatable Rac Controls the Motility of Living Cells. Nature, 461, 2009
1QUQ	COMPLEX OF REPLICATION PROTEIN A SUBUNITS RPA14 AND RPA32 分子名称: PROTEIN (REPLICATION PROTEIN A 14 KD SUBUNIT), PROTEIN (REPLICATION PROTEIN A 32 KD SUBUNIT) 著者 Bochkarev, A, Bochkareva, E, Frappier, L, Edwards, A.M. 登録日 1999-07-02 公開日 1999-08-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding. EMBO J., 18, 1999
6DKK	Structure of BoNT 分子名称: Botulinum neurotoxin type A, PHOSPHATE ION 著者 Lam, K, Jin, R. 登録日 2018-05-29 公開日 2018-12-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1. Nat Commun, 9, 2018

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