7PMX
| HsPepT1 bound to Ala-Phe in the outward facing open conformation | 分子名称: | ALA-PHE, Solute carrier family 15 member 1 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-03 | 公開日 | 2021-10-20 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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7PMY
| HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation | 分子名称: | ALA-PHE, Solute carrier family 15 member 2 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-04 | 公開日 | 2021-10-20 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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8EMQ
| Mouse apoferritin heavy chain with zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed, ... | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.66 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
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7PN1
| Apo HsPepT1 in the outward facing open conformation | 分子名称: | Solute carrier family 15 member 1 | 著者 | Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C. | 登録日 | 2021-09-04 | 公開日 | 2021-10-20 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes. Sci Adv, 7, 2021
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6NNN
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6YJ4
| Structure of Yarrowia lipolytica complex I at 2.7 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Acyl carrier protein ACPM1 of NADH:Ubiquinone Oxidoreductase (Complex I), Acyl carrier protein ACPM2 of NADH:Ubiquinone Oxidoreductase (Complex I), ... | 著者 | Hirst, J, Grba, D. | 登録日 | 2020-04-02 | 公開日 | 2020-08-12 | 最終更新日 | 2021-03-17 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Mitochondrial complex I structure reveals ordered water molecules for catalysis and proton translocation. Nat.Struct.Mol.Biol., 27, 2020
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8EN7
| Mouse apoferritin heavy chain without zinc determined using single-particle cryo-EM with Apollo camera. | 分子名称: | FE (III) ION, Ferritin heavy chain, N-terminally processed | 著者 | Peng, R, Fu, X, Mendez, J.H, Randolph, P.H, Bammes, B, Stagg, S.M. | 登録日 | 2022-09-28 | 公開日 | 2022-12-21 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.68 Å) | 主引用文献 | Characterizing the resolution and throughput of the Apollo direct electron detector. J Struct Biol X, 7, 2023
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6BJG
| CIRV p19 mutant T111H in complex with siRNA | 分子名称: | RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19 | 著者 | Foss, D.V, Schirle, N, Pezacki, J.P, Macrae, I.J. | 登録日 | 2017-11-06 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs. Febs Open Bio, 9, 2019
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6Y9W
| Structure of the native full-length HIV-1 capsid protein in complex with Cyclophilin A from helical assembly (-13,8) | 分子名称: | Gag-Pol polyprotein, Peptidyl-prolyl cis-trans isomerase A | 著者 | Ni, T, Gerard, S, Zhao, G, Ning, J, Zhang, P. | 登録日 | 2020-03-10 | 公開日 | 2020-08-19 | 最終更新日 | 2021-02-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Intrinsic curvature of the HIV-1 CA hexamer underlies capsid topology and interaction with cyclophilin A. Nat.Struct.Mol.Biol., 27, 2020
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7R5J
| Human nuclear pore complex (dilated) | 分子名称: | Aladin, E3 SUMO-protein ligase RanBP2, Nuclear pore complex protein Nup107, ... | 著者 | Mosalaganti, S, Obarska-Kosinska, A, Siggel, M, Taniguchi, R, Turonova, B, Zimmerli, C.E, Buczak, K, Schmidt, F.H, Margiotta, E, Mackmull, M.T, Hagen, W.J.H, Hummer, G, Kosinski, J, Beck, M. | 登録日 | 2022-02-10 | 公開日 | 2022-09-21 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (50 Å) | 主引用文献 | AI-based structure prediction empowers integrative structural analysis of human nuclear pores Science, 376, 2022
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6BY0
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6ZTY
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6BHP
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6O01
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6WE3
| Human PARP14 (ARTD8), catalytic fragment in complex with compound 3 | 分子名称: | 1,2-ETHANEDIOL, 2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}-8-methylquinazolin-4(3H)-one, DI(HYDROXYETHYL)ETHER, ... | 著者 | Swinger, K.S, Schenkel, L.B, Kuntz, K.W. | 登録日 | 2020-04-01 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants. Cell Chem Biol, 28, 2021
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6WE2
| Human PARP14 (ARTD8), catalytic fragment in complex with RBN012759 | 分子名称: | 1,2-ETHANEDIOL, 7-(cyclopropylmethoxy)-5-fluoro-2-{[(trans-4-hydroxycyclohexyl)sulfanyl]methyl}quinazolin-4(3H)-one, Isoform 1 of Protein mono-ADP-ribosyltransferase PARP14 | 著者 | Swinger, K.K, Schenkel, L.B, Kuntz, K.W. | 登録日 | 2020-04-01 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants. Cell Chem Biol, 28, 2021
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6BJH
| CIRV p19 mutant T111S in complex with siRNA | 分子名称: | RNA (5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*GP*AP*AP*UP*AP*CP*UP*UP*CP*GP*AP*UP*U)-3'), RNA (5'-R(P*UP*CP*GP*AP*AP*GP*UP*AP*UP*UP*CP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3'), RNA silencing suppressor p19 | 著者 | Foss, D.V, Schirle, N.T, MacRae, I.J, Pezacki, J.P. | 登録日 | 2017-11-06 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural insights into interactions between viral suppressor of RNA silencing protein p19 mutants and small RNAs. Febs Open Bio, 9, 2019
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6WE4
| Human PARP14 (ARTD8), catalytic fragment in complex with compound 2 | 分子名称: | 1,2-ETHANEDIOL, 2-methyl-3,5,6,7-tetrahydro-4H-cyclopenta[4,5]thieno[2,3-d]pyrimidin-4-one, 8-methyl-2-{[(pyridin-4-yl)sulfanyl]methyl}quinazolin-4(3H)-one, ... | 著者 | Swinger, K.S, Schenkel, L.B, Kuntz, K.W. | 登録日 | 2020-04-01 | 公開日 | 2021-03-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants. Cell Chem Biol, 28, 2021
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6ZMM
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6O2Q
| Acetylated Microtubules | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Eshun-Wilson, L, Zhang, R, Portran, D, Nachury, M.V, Toso, D, Lohr, T, Vendruscolo, M, Bonomi, M, Fraser, J.S, Nogales, E. | 登録日 | 2019-02-24 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Effects of alpha-tubulin acetylation on microtubule structure and stability. Proc.Natl.Acad.Sci.USA, 116, 2019
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6NZE
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6B0L
| KLP10A-AMPPNP in complex with a microtubule | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein Klp10A, ... | 著者 | Benoit, M.P.M.H, Asenjo, A.B, Sosa, H. | 登録日 | 2017-09-14 | 公開日 | 2018-05-02 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | Cryo-EM reveals the structural basis of microtubule depolymerization by kinesin-13s. Nat Commun, 9, 2018
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7RML
| Neisseria meningitidis Methylenetetrahydrofolate reductase in complex with FAD | 分子名称: | 5,10-methylenetetrahydrofolate reductase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Pederick, J.L, Wegener, K.L, Salaemae, W, Bruning, J.B. | 登録日 | 2021-07-27 | 公開日 | 2022-11-02 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Biochemical and structural characterization of meningococcal methylenetetrahydrofolate reductase. Protein Sci., 32, 2023
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6WHO
| Histone deacetylases complex with peptide macrocycles | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Histone deacetylase 2, SODIUM ION, ... | 著者 | Bera, A.K, Hosseinzadeh, P, Watson, P, Baker, D. | 登録日 | 2020-04-08 | 公開日 | 2021-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites. Nat Commun, 12, 2021
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6WHN
| Histone deacetylases complex with peptide macrocycles | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, DI(HYDROXYETHYL)ETHER, Histone deacetylase 2, ... | 著者 | Bera, A.K, Hosseinzadeh, P, Watson, P, Baker, D. | 登録日 | 2020-04-08 | 公開日 | 2021-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites. Nat Commun, 12, 2021
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