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6XXL
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Crystal Structure of Human Deoxyhypusine Synthase in complex with spermine
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, ACETATE ION, ...
著者Wator, E, Wilk, P, Grudnik, P.
登録日2020-01-27
公開日2020-04-15
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Half Way to Hypusine-Structural Basis for Substrate Recognition by Human Deoxyhypusine Synthase.
Biomolecules, 10, 2020
8QND
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BU of 8qnd by Molmil
Crystal structure of the ribonucleoside hydrolase C from Lactobacillus reuteri
分子名称: CALCIUM ION, Inosine-uridine nucleoside N-ribohydrolase
著者Matyuta, I.O, Minyaev, M.E, Shaposhnikov, L.A, Pometun, E.V, Tishkov, V.I, Popov, V.O, Boyko, K.M.
登録日2023-09-26
公開日2023-12-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-Functional Examination of Novel Ribonucleoside Hydrolase C (RihC) from Limosilactobacillus reuteri LR1.
Int J Mol Sci, 25, 2023
4MD8
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Crystal Structure of full-length symmetric CK2 holoenzyme with mutated alpha subunit (F121E)
分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION
著者Lolli, G, Ranchio, A, Battistutta, R.
登録日2013-08-22
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture.
Acs Chem.Biol., 9, 2014
8FVB
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E coli. CTP synthase in complex with CTP
分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MALONIC ACID
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVE
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E coli. CTP synthase in complex with CTP (potassium malonate + 100 mM MgCl2)
分子名称: CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
8FVA
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E coli. CTP synthase in complex with F-araCTP
分子名称: 4-amino-1-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one, CTP synthase, MALONIC ACID, ...
著者Holyoak, T, McLeod, M.J, Tran, N.
登録日2023-01-18
公開日2023-05-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A metal-dependent conformational change provides a structural basis for the inhibition of CTP synthase by gemcitabine-5'-triphosphate.
Protein Sci., 32, 2023
6EB9
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Crystal Structure of the Nipah Virus Phosphoprotein Multimerization Domain Delta 542-544
分子名称: Phosphoprotein
著者Bruhn, J.F, Saphire, E.O.
登録日2018-08-06
公開日2019-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Conserved Basic Patch and Central Kink in the Nipah Virus Phosphoprotein Multimerization Domain Are Essential for Polymerase Function.
Structure, 27, 2019
7SMG
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BU of 7smg by Molmil
Crystal structure of a (p)ppApp hydrolase from Bacteroides caccae
分子名称: (p)ppApp hydrolase, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Ahmad, S, Alexei, A.G, Tsang, K.K, Trilesky, S, Kim, Y, Whitney, J.C.
登録日2021-10-25
公開日2022-11-09
最終更新日2023-05-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of a broadly conserved family of enzymes that hydrolyze (p)ppApp.
Proc.Natl.Acad.Sci.USA, 120, 2023
7ZQY
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Chaetomium thermophilum Rad50 Zn hook
分子名称: DH domain-containing protein, ZINC ION
著者Lammens, K, Rotheneder, M, Stakyte, K.
登録日2022-05-03
公開日2022-12-28
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Cryo-EM structure of the Mre11-Rad50-Nbs1 complex reveals the molecular mechanism of scaffolding functions.
Mol.Cell, 83, 2023
4PQL
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N-Terminal domain of DNA binding protein
分子名称: 1,2-ETHANEDIOL, Truncated replication protein RepA
著者Schumacher, M.A, Chinnam, N, Tonthat, N.K.
登録日2014-03-03
公開日2014-06-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.444 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
7ZJE
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BU of 7zje by Molmil
C16-2
分子名称: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
著者Zhang, L, Gourdon, P, Zygmunt, P.M.
登録日2022-04-10
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJG
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Probenecid
分子名称: Transient receptor potential cation channel subfamily V member 2
著者Zhang, L, Gourdon, P, Zygmunt, P.M.
登録日2022-04-11
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJI
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BU of 7zji by Molmil
Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
分子名称: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
著者Zhang, L, Gourdon, P, Zygmunt, P.M.
登録日2022-04-11
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJH
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BU of 7zjh by Molmil
TRPV2-C16+Pro-2
分子名称: Transient receptor potential cation channel subfamily V member 2
著者Zhang, L, Gourdon, P, Zygmunt, P.M.
登録日2022-04-11
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (3.39 Å)
主引用文献Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
7ZJD
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BU of 7zjd by Molmil
Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
分子名称: Transient receptor potential cation channel subfamily V member 2,Enhanced green fluorescent protein
著者Zhang, L, Gourdon, P, Zygmunt, P.M.
登録日2022-04-10
公開日2023-01-18
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献Cannabinoid non-cannabidiol site modulation of TRPV2 structure and function.
Nat Commun, 13, 2022
4PNC
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BU of 4pnc by Molmil
E. COLI METHIONINE AMINOPEPTIDASE IN COMPLEX WITH INHIBITOR 7-METHOXY-2-METHYLEN-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE
分子名称: (2S)-7-methoxy-2-methyl-3,4-dihydronaphthalen-1(2H)-one, COBALT (II) ION, Methionine aminopeptidase, ...
著者Scheidig, A.J, Altmeyer, M, Klein, C.D.
登録日2014-05-23
公開日2014-07-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases.
Bioorg.Med.Chem.Lett., 24, 2014
4MD7
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BU of 4md7 by Molmil
Crystal Structure of full-length symmetric CK2 holoenzyme
分子名称: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION
著者Lolli, G, Ranchio, A, Battistutta, R.
登録日2013-08-22
公開日2013-11-20
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Active Form of the Protein Kinase CK2 alpha 2 beta 2 Holoenzyme Is a Strong Complex with Symmetric Architecture.
Acs Chem.Biol., 9, 2014
4P9O
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Complex of Voltage-gated ion channel in a the presence of channel blocking compound
分子名称: BROMIDE ION, HEGA-10, Ion transport protein
著者Naylor, C.E, Bagneris, C, Wallace, B.A.
登録日2014-04-04
公開日2014-06-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PFN
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BU of 4pfn by Molmil
Crystal structure of Plasmodium vivax SHMT with L-serine Schiff base
分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, SERINE, ...
著者Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U.
登録日2014-04-30
公開日2014-12-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control.
Acta Crystallogr.,Sect.D, 70, 2014
4HRH
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BU of 4hrh by Molmil
Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with SMARCA3 Peptide
分子名称: Helicase-like transcription factor, Protein S100-A10, Annexin A2, ...
著者Gao, P, Patel, D.J.
登録日2012-10-27
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.001 Å)
主引用文献SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
4HRG
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Crystal Structure of p11-Annexin A2(N-terminal) Fusion Protein in Complex with AHNAK1 Peptide
分子名称: Neuroblast differentiation-associated protein AHNAK, Protein S100-A10
著者Gao, P, Patel, D.J.
登録日2012-10-27
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.0001 Å)
主引用文献SMARCA3, a Chromatin-Remodeling Factor, Is Required for p11-Dependent Antidepressant Action.
Cell(Cambridge,Mass.), 152, 2013
8JJ5
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Porcine uroplakin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Tetraspanin, ...
著者Oda, T, Yanagisawa, H, Kikkawa, M.
登録日2023-05-29
公開日2023-06-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM elucidates the uroplakin complex structure within liquid-crystalline lipids in the porcine urothelial membrane.
Commun Biol, 6, 2023
4PTA
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BU of 4pta by Molmil
Structure of MDR initiator
分子名称: Replication initiator protein
著者Schumacher, M.A.
登録日2014-03-10
公開日2014-06-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6003 Å)
主引用文献Mechanism of staphylococcal multiresistance plasmid replication origin assembly by the RepA protein.
Proc.Natl.Acad.Sci.USA, 111, 2014
4PFF
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BU of 4pff by Molmil
Crystal structure of Plasmodium vivax SHMT with PLP Schiff base
分子名称: PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase, putative
著者Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U.
登録日2014-04-29
公開日2014-12-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control.
Acta Crystallogr.,Sect.D, 70, 2014
4PA7
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Structure of NavMS pore and C-terminal domain crystallised in presence of channel blocking compound
分子名称: DODECAETHYLENE GLYCOL, HEGA-10, Ion transport protein, ...
著者Naylor, C.E, Bagneris, C, Wallace, B.A.
登録日2014-04-07
公開日2014-06-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism.
Proc.Natl.Acad.Sci.USA, 111, 2014

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