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4YG8
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CRYSTAL STRUCTURE OF THE CHS5-CHS6 EXOMER CARGO ADAPTOR COMPLEX
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chitin biosynthesis protein CHS5, Chitin biosynthesis protein CHS6, ...
著者Paczkowski, J.E, Richardson, B.C, Strassner, A.M, Fromme, J.C.
登録日2015-02-26
公開日2015-03-11
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The exomer cargo adaptor structure reveals a novel GTPase-binding domain.
Embo J., 31, 2012
7TNK
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Complex GNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNO
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Complex GGGN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNM
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Complex GNGN2 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.74 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNL
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Complex GNGN1 of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNN
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Complex GGNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNJ
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Complex NNNN of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (4.02 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
7TNP
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Complex GGGG of AMPA-subtype iGluR GluA2 in complex with auxiliary subunit gamma2 (Stargazin) at low glutamate concentration (20 uM) in the presence of cyclothiazide (100 uM)
分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Isoform Flip of Glutamate receptor 2,Voltage-dependent calcium channel gamma-3 subunit chimera
著者Yelshanskaya, M.V, Sobolevsky, A.I.
登録日2022-01-21
公開日2022-04-20
最終更新日2022-05-18
実験手法ELECTRON MICROSCOPY (3.96 Å)
主引用文献Opening of glutamate receptor channel to subconductance levels.
Nature, 605, 2022
1POW
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BU of 1pow by Molmil
THE REFINED STRUCTURES OF A STABILIZED MUTANT AND OF WILD-TYPE PYRUVATE OXIDASE FROM LACTOBACILLUS PLANTARUM
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, PYRUVATE OXIDASE, ...
著者Muller, Y.A, Schulz, G.E.
登録日1993-11-09
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from Lactobacillus plantarum.
J.Mol.Biol., 237, 1994
1NG4
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Structure of ThiO (glycine oxidase) from Bacillus subtilis
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Glycine oxidase, HYDROGEN PEROXIDE, ...
著者Settembre, E.C, Dorrestein, P.C, Park, J, Augustine, A, Begley, T.P, Ealick, S.E.
登録日2002-12-16
公開日2003-04-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry, 42, 2003
1NG3
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Complex of ThiO (glycine oxidase) with acetyl-glycine
分子名称: ACETYLAMINO-ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Glycine oxidase, ...
著者Settembre, E.C, Dorrestein, P.C, Park, J, Augustine, A, Begley, T.P, Ealick, S.E.
登録日2002-12-16
公開日2003-04-08
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry, 42, 2003
7QUN
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BU of 7qun by Molmil
CryoEM structure of mammalian AAP in complex with Meropenem
分子名称: (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Acylamino-acid-releasing enzyme
著者Kiss-Szeman, A.J, Harmat, V, Straner, P, Jakli, I, Menyhard, K.D, Masiulis, S, Perczel, A.
登録日2022-01-18
公開日2022-11-16
最終更新日2023-02-01
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献A carbapenem antibiotic inhibiting a mammalian serine protease: structure of the acylaminoacyl peptidase-meropenem complex.
Chem Sci, 13, 2022
7QC5
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Crystal structure of human wild type transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound
分子名称: (3-fluoranyl-5-oxidanyl-phenyl)-[3-nitro-4,5-bis(oxidanyl)phenyl]methanone, Transthyretin
著者Varejao, N, Pinheiro, F, Pallares, I, Ventura, S, Reverter, D.
登録日2021-11-22
公開日2022-11-30
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation.
J.Med.Chem., 65, 2022
5M4O
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Crystal structure of hydroquinone 1,2-dioxygenase from Sphingomonas sp. TTNP3 in complex with 4-nitrophenol
分子名称: FE (III) ION, Hydroquinone dioxygenase large subunit, Hydroquinone dioxygenase small subunit, ...
著者Ferraroni, M, Da Vela, S, Scozzafava, A, Kolvenbach, B, Corvini, P.F.X.
登録日2016-10-18
公開日2017-09-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The crystal structures of native hydroquinone 1,2-dioxygenase from Sphingomonas sp. TTNP3 and of substrate and inhibitor complexes.
Biochim. Biophys. Acta, 1865, 2017
1B2P
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BU of 1b2p by Molmil
NATIVE MANNOSE-SPECIFIC BULB LECTIN FROM SCILLA CAMPANULATA (BLUEBELL) AT 1.7 ANGSTROMS RESOLUTION
分子名称: PROTEIN (LECTIN)
著者Wood, S.D, Wright, L.M, Reynolds, C.D, Rizkallah, P.J, Allen, A.K, Peumans, W.J, Van Damme, E.J.M.
登録日1998-11-30
公開日1999-07-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the native (unligated) mannose-specific bulb lectin from Scilla campanulata (bluebell) at 1.7 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
8DRP
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BU of 8drp by Molmil
Focus/local refined map in C4 of signal subtracted RyR1 particles
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, Ryanodine receptor 1, ...
著者Haji-Ghassemi, O, Van Petegm, F.
登録日2022-07-21
公開日2023-05-31
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Sci Adv, 9, 2023
5NMA
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BU of 5nma by Molmil
Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain
分子名称: (1~{R},3~{S},5~{Z})-5-[(2~{E})-2-[(1~{R},3~{a}~{S},7~{a}~{R})-7~{a}-methyl-1-[(1~{S})-1-[(2~{S},5~{S})-5-(2-oxidanylpropan-2-yl)oxolan-2-yl]ethyl]-2,3,3~{a},5,6,7-hexahydro-1~{H}-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol, Nuclear receptor coactivator 1, Vitamin D3 receptor A
著者Rochel, N, Belorusova, A.Y.
登録日2017-04-05
公開日2017-05-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-activity relationship study of vitamin D analogs with oxolane group in their side chain.
Eur J Med Chem, 134, 2017
5NQV
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Structure of the Arabidopsis Thaliana TOPLESS N-terminal domain
分子名称: EAR motif of IAA27, GLYCEROL, L(+)-TARTARIC ACID, ...
著者Nanao, M.H, Arevalillo, M.R, Vinos-Poyo, T, Parcy, F, Dumas, R.
登録日2017-04-21
公開日2017-07-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the Arabidopsis TOPLESS corepressor provides insight into the evolution of transcriptional repression.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1JSW
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NATIVE L-ASPARTATE AMMONIA LYASE
分子名称: ACETATE ION, L-ASPARTATE AMMONIA-LYASE, beta-D-glucopyranose
著者Shi, W, Dunbar, J, Farber, G.K.
登録日1997-02-19
公開日1997-06-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The structure of L-aspartate ammonia-lyase from Escherichia coli.
Biochemistry, 36, 1997
2OSZ
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BU of 2osz by Molmil
Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding
分子名称: Nucleoporin p58/p45
著者Melcak, I, Hoelz, A, Blobel, G.
登録日2007-02-06
公開日2007-04-10
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structure of Nup58/45 suggests flexible nuclear pore diameter by intermolecular sliding.
Science, 315, 2007
1GAD
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BU of 1gad by Molmil
COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY
分子名称: D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O.
登録日1995-10-24
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
J.Mol.Biol., 257, 1996
5MJ7
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BU of 5mj7 by Molmil
Structure of the C. elegans nucleoside hydrolase
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Uncharacterized protein
著者Versees, W, Singh, R.K.
登録日2016-11-30
公開日2017-03-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis.
Protein Sci., 26, 2017
1GAE
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BU of 1gae by Molmil
COMPARISON OF THE STRUCTURES OF WILD TYPE AND A N313T MUTANT OF ESCHERICHIA COLI GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASES: IMPLICATION FOR NAD BINDING AND COOPERATIVITY
分子名称: D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Duee, E, Olivier-Deyris, L, Fanchon, E, Corbier, C, Branlant, G, Dideberg, O.
登録日1995-10-24
公開日1996-03-08
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Comparison of the structures of wild-type and a N313T mutant of Escherichia coli glyceraldehyde 3-phosphate dehydrogenases: implication for NAD binding and cooperativity.
J.Mol.Biol., 257, 1996
2P9C
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BU of 2p9c by Molmil
Crystal structure of serine bound G336V mutant of E.coli phosphoglycerate dehydrogenase
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, D-3-phosphoglycerate dehydrogenase, SERINE
著者Dey, S, Sacchettini, J.C.
登録日2007-03-24
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献The Effect of Hinge Mutations on Effector Binding and Domain Rotation in Escherichia coli D-3-Phosphoglycerate Dehydrogenase
J.Biol.Chem., 282, 2007
6Z9U
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BU of 6z9u by Molmil
Crystal structure of a TSEN15-34 heterodimer.
分子名称: GLYCEROL, tRNA-splicing endonuclease subunit Sen15, tRNA-splicing endonuclease subunit Sen34
著者Trowitzsch, S, Sekulovski, S.
登録日2020-06-04
公開日2021-06-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.10001779 Å)
主引用文献Assembly defects of human tRNA splicing endonuclease contribute to impaired pre-tRNA processing in pontocerebellar hypoplasia.
Nat Commun, 12, 2021

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