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8UI8
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Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state 3
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase family AAA domain-containing protein 5, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-10
公開日2024-05-29
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader.
Nat.Struct.Mol.Biol., 2024
8UNJ
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BU of 8unj by Molmil
Atomic model of the human CTF18-RFC alone in the apo state (State 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, MAGNESIUM ION, ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-19
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UMW
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Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding state (state 4)
分子名称: ADENOSINE-5'-DIPHOSPHATE, Chromosome transmission fidelity protein 18 homolog, DNA (20-MER), ...
著者Wang, F, He, Q, Li, H.
登録日2023-10-18
公開日2024-05-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC.
Proc.Natl.Acad.Sci.USA, 121, 2024
7U1C
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BU of 7u1c by Molmil
Structure of EstG crystalized with SO4 and Tris
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase domain-containing protein, SODIUM ION, ...
著者Gabelli, S.B, Chen, Z.
登録日2022-02-20
公開日2023-01-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献EstG is a novel esterase required for cell envelope integrity in Caulobacter.
Curr.Biol., 33, 2023
7TND
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BU of 7tnd by Molmil
The crystal structure of CYP199A4 bound to 4-phenoxybenzoic acid
分子名称: 4-phenoxybenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-20
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.825 Å)
主引用文献Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.
Chemistry, 28, 2022
7TNF
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BU of 7tnf by Molmil
The crystal structure of F298V CYP199A4 bound to 4-phenylbenzoic acid
分子名称: CHLORIDE ION, Cytochrome P450, MAGNESIUM ION, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-21
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.539 Å)
主引用文献Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.
Chemistry, 28, 2022
7TP6
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BU of 7tp6 by Molmil
The crystal structure of T252E CYP199A4 bound to 4-methylthiobenzoic acid
分子名称: 4-methylsulfanylbenzoic acid, ACETATE ION, CHLORIDE ION, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-25
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions.
Chemistry, 28, 2022
7TNU
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BU of 7tnu by Molmil
The crystal structure of F298V CYP199A4 bound to 4-cyclohexylbenzoic acid
分子名称: 4-cyclohexylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-21
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.584 Å)
主引用文献Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering.
Chemistry, 28, 2022
7TP5
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The crystal structure of T252E CYP199A4 bound to 4-ethylthiobenzoic acid
分子名称: 4-(ethylsulfanyl)benzoic acid, ACETATE ION, CHLORIDE ION, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-25
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions.
Chemistry, 28, 2022
7TQM
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BU of 7tqm by Molmil
The crystal structure of D251N CYP199A4 bound to 4-methylthiobenzoic acid
分子名称: 4-methylsulfanylbenzoic acid, CHLORIDE ION, Cytochrome P450, ...
著者Podgorski, M, Bell, S.G.
登録日2022-01-26
公開日2023-01-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.438 Å)
主引用文献Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions.
Chemistry, 28, 2022
7OSE
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BU of 7ose by Molmil
cytochrome bd-II type oxidase with bound aurachin D
分子名称: Aurachin D, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Cytochrome bd-II ubiquinol oxidase subunit 1, ...
著者Grauel, A, Kaegi, J, Rasmussen, T, Wohlwend, D, Boettcher, B, Friedrich, T.
登録日2021-06-08
公開日2021-11-17
最終更新日2023-09-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of Escherichia coli cytochrome bd-II type oxidase with bound aurachin D.
Nat Commun, 12, 2021
8VX0
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BU of 8vx0 by Molmil
CRYSTAL STRUCTURE OF CYP2C9*14 IN COMPLEX WITH LOSARTAN
分子名称: Cytochrome P450 2C9, PHOSPHATE ION, POTASSIUM ION, ...
著者Shah, M.B.
登録日2024-02-02
公開日2024-06-12
最終更新日2024-06-26
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural and biophysical analysis of cytochrome P450 2C9*14 and *27 variants in complex with losartan.
J.Inorg.Biochem., 258, 2024
7T33
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BU of 7t33 by Molmil
The structure of Haemophilus influenzae Rd KW20 nitroreductase complexed with nicotinic acid
分子名称: FLAVIN MONONUCLEOTIDE, NICOTINIC ACID, Putative NAD(P)H nitroreductase, ...
著者Wanniarachchi, T.N, Bruner, S.D.
登録日2021-12-06
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Biochemical and structural characterization of Haemophilus influenzae nitroreductase in metabolizing nitroimidazoles.
Rsc Chem Biol, 3, 2022
8WB4
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BU of 8wb4 by Molmil
Structure of PSII-ACPII supercomplex from cryptophyte algae
分子名称: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ...
著者Li, X.Y, Mao, Z.Y, Shen, J.R, Han, G.Y.
登録日2023-09-08
公開日2024-06-05
実験手法ELECTRON MICROSCOPY (2.47 Å)
主引用文献Structure and distinct supramolecular organization of a PSII-ACPII dimer from a cryptophyte alga Chroomonas placoidea.
Nat Commun, 15, 2024
3JC8
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Architectural model of the type IVa pilus machine in a piliated state
分子名称: LysM domain protein, PilA, PilN, ...
著者Chang, Y.-W, Rettberg, L.A, Jensen, G.J.
登録日2015-11-24
公開日2016-03-16
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Architecture of the type IVa pilus machine.
Science, 351, 2016
7TB7
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BU of 7tb7 by Molmil
Crystal structure of D179N KPC-2 beta-lactamase
分子名称: CITRIC ACID, Carbapenem-hydrolyzing beta-lactamase KPC
著者van den Akker, F, Alsenani, T.
登録日2021-12-21
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献Structural Characterization of the D179N and D179Y Variants of KPC-2 beta-Lactamase: Omega-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam.
Antimicrob.Agents Chemother., 66, 2022
7T6C
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BU of 7t6c by Molmil
E. coli dihydroorotate dehydrogenase bound to the ubiquinone surrogate DCIP
分子名称: 2,6-bis(chloranyl)-4-[(4-hydroxyphenyl)amino]phenol, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Dihydroorotate dehydrogenase (quinone), ...
著者Horwitz, S.M, Ambarian, J.A, Davis, K.M.
登録日2021-12-13
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines.
Rsc Chem Biol, 3, 2022
7T5K
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BU of 7t5k by Molmil
E. coli dihydroorotate dehydrogenase bound to the inhibitor HQNO
分子名称: 2-HEPTYL-4-HYDROXY QUINOLINE N-OXIDE, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ...
著者Horwitz, S.M, Ambarian, J.A, Davis, K.M.
登録日2021-12-12
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines.
Rsc Chem Biol, 3, 2022
7T6H
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BU of 7t6h by Molmil
E. coli dihydroorotate dehydrogenase
分子名称: Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, OROTIC ACID
著者Horwitz, S.M, Ambarian, J.A, Davis, K.M.
登録日2021-12-13
公開日2022-03-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.42 Å)
主引用文献Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines.
Rsc Chem Biol, 3, 2022
7SP3
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BU of 7sp3 by Molmil
E. coli RppH bound to Ap4A
分子名称: BIS(ADENOSINE)-5'-TETRAPHOSPHATE, CHLORIDE ION, FLUORIDE ION, ...
著者Serganov, A.A, Vasilyev, N, Nuthanakanti, A.
登録日2021-11-02
公開日2022-03-09
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A distinct RNA recognition mechanism governs Np 4 decapping by RppH.
Proc.Natl.Acad.Sci.USA, 119, 2022
7TBX
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BU of 7tbx by Molmil
Crystal structure of D179Y KPC-2 beta-lactamase
分子名称: Carbapenem-hydrolyzing beta-lactamase KPC
著者van den Akker, F, Alsenani, T.
登録日2021-12-22
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.16 Å)
主引用文献Structural Characterization of the D179N and D179Y Variants of KPC-2 beta-Lactamase: Omega-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam.
Antimicrob.Agents Chemother., 66, 2022
7T5Y
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BU of 7t5y by Molmil
E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ
分子名称: 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ...
著者Horwitz, S.M, Ambarian, J.A, Davis, K.M.
登録日2021-12-13
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines.
Rsc Chem Biol, 3, 2022
7TC1
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Crystal structure of D179N KPC-2 beta-lactamase in complex with vaborbactam
分子名称: Carbapenem-hydrolyzing beta-lactamase KPC, PHOSPHATE ION, Vaborbactam
著者van den Akker, F, Alsenani, T.
登録日2021-12-22
公開日2022-03-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献Structural Characterization of the D179N and D179Y Variants of KPC-2 beta-Lactamase: Omega-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam.
Antimicrob.Agents Chemother., 66, 2022
7TAD
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BU of 7tad by Molmil
CryoEM structure of the (NPR1)2-(TGA3)2 complex
分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ...
著者Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P.
登録日2021-12-20
公開日2022-03-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
7TAC
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Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex
分子名称: PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ...
著者Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P.
登録日2021-12-20
公開日2022-03-16
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022

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件を2024-08-14に公開中

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