7T6H
E. coli dihydroorotate dehydrogenase
Summary for 7T6H
Entry DOI | 10.2210/pdb7t6h/pdb |
Related | 7T5K 7T5Y 7T6C |
Descriptor | Dihydroorotate dehydrogenase (quinone), OROTIC ACID, FLAVIN MONONUCLEOTIDE, ... (4 entities in total) |
Functional Keywords | inhibitor, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 2 |
Total formula weight | 81795.40 |
Authors | Horwitz, S.M.,Ambarian, J.A.,Davis, K.M. (deposition date: 2021-12-13, release date: 2022-03-02, Last modification date: 2024-02-28) |
Primary citation | Horwitz, S.M.,Blue, T.C.,Ambarian, J.A.,Hoshino, S.,Seyedsayamdost, M.R.,Davis, K.M. Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3:420-425, 2022 Cited by PubMed: 35441142DOI: 10.1039/d1cb00255d PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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