5L34
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8PFK
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![BU of 8pfk by Molmil](/molmil-images/mine/8pfk) | RNA structure with 1-methylpseudoridine, C2 space group | 分子名称: | MAGNESIUM ION, RNA (12-mer) | 著者 | Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. | 登録日 | 2023-06-16 | 公開日 | 2024-01-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.321 Å) | 主引用文献 | RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines. Chemmedchem, 19, 2024
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5L3X
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6UOM
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![BU of 6uom by Molmil](/molmil-images/mine/6uom) | Y271G DNA polymerase beta ternary complex with templating adenine and incoming r8-oxo-GTP | 分子名称: | 1,2-ETHANEDIOL, 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, 8-OXO-GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Smith, M.R, Freudenthal, B.D. | 登録日 | 2019-10-15 | 公開日 | 2020-01-08 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Molecular and structural characterization of oxidized ribonucleotide insertion into DNA by human DNA polymerase beta. J.Biol.Chem., 295, 2020
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7KZ2
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6F2F
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![BU of 6f2f by Molmil](/molmil-images/mine/6f2f) | Crystal structure of Protease 1 from Pyrococcus Horikoshii co-cystallized in presence of 10 mM Tb-Xo4 and ammonium sulfate. | 分子名称: | Deglycase PH1704, Dihydroxyacetone, SULFATE ION, ... | 著者 | Engilberge, S, Riobe, F, Di Pietro, S, Franzetti, B, Girard, E, Dumont, E, Maury, O. | 登録日 | 2017-11-24 | 公開日 | 2018-10-03 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Unveiling the Binding Modes of the Crystallophore, a Terbium-based Nucleating and Phasing Molecular Agent for Protein Crystallography. Chemistry, 24, 2018
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8A9L
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![BU of 8a9l by Molmil](/molmil-images/mine/8a9l) | Cryo-EM structure of alpha-synuclein filaments from Parkinson's disease and dementia with Lewy bodies | 分子名称: | Alpha-synuclein, Unknown fragment | 著者 | Yang, Y, Shi, Y, Schweighauser, M, Zhang, X.J, Kotecha, A, Murzin, A.G, Garringer, H.J, Cullinane, P, Saito, Y, Foroud, T, Warner, T.T, Hasegawa, K, Vidal, R, Murayama, S, Revesz, T, Ghetti, B, Hasegawa, M, Lashley, T, Scheres, H.W.S, Goedert, M. | 登録日 | 2022-06-28 | 公開日 | 2022-08-31 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structures of alpha-synuclein filaments from human brains with Lewy pathology. Nature, 610, 2022
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8PTQ
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![BU of 8ptq by Molmil](/molmil-images/mine/8ptq) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l | 分子名称: | 1,2-ETHANEDIOL, Monoglyceride lipase, methyl 4-[(2~{S},3~{R})-3-(4-fluorophenyl)-1-(1-methanoylpiperidin-4-yl)-4-oxidanylidene-azetidin-2-yl]benzoate | 著者 | Butini, S, Grether, U, Benz, J, Leibrock, L, Maramai, S, Papa, A, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | 登録日 | 2023-07-14 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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5TGM
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![BU of 5tgm by Molmil](/molmil-images/mine/5tgm) | Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | 著者 | Melnikov, S, Mailliot, J, Yusupov, M. | 登録日 | 2016-09-28 | 公開日 | 2017-01-18 | 最終更新日 | 2022-12-07 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
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8ZHP
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![BU of 8zhp by Molmil](/molmil-images/mine/8zhp) | Dimer of SARS-CoV-2 S1 in complex with H18 and R1-32 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of H18 Fab, Heavy chain of R1-32 Fab, ... | 著者 | Yan, Q, Gao, X, Liu, B, Hou, R, He, P, Li, Z, Chen, Q, Wang, J, He, J, Chen, L, Zhao, J, Xiong, X. | 登録日 | 2024-05-11 | 公開日 | 2024-08-21 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | Antibodies utilizing VL6-57 light chains target a convergent cryptic epitope on SARS-CoV-2 spike protein helping to drive the genesis of Omicron variants To Be Published
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5IPB
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6EUH
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![BU of 6euh by Molmil](/molmil-images/mine/6euh) | The GH43, Beta 1,3 Galactosidase, BT3683 with galactodeoxynojirimycin | 分子名称: | (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol, Beta-glucanase, CALCIUM ION | 著者 | Cartmell, A, Gilbert, H.J. | 登録日 | 2017-10-30 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nat Microbiol, 3, 2018
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6ART
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![BU of 6art by Molmil](/molmil-images/mine/6art) | Aspergillus fumigatus Cytosolic Thiolase: Apo enzyme in complex with cesium ions | 分子名称: | Acetyl-CoA acetyltransferase, CESIUM ION, CHLORIDE ION, ... | 著者 | Marshall, A.C, Bond, C.S, Bruning, J.B. | 登録日 | 2017-08-23 | 公開日 | 2018-05-30 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of Aspergillus fumigatus Cytosolic Thiolase: Trapped Tetrahedral Reaction Intermediates and Activation by Monovalent Cations Acs Catalysis, 8(3), 2018
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8PM0
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8PTC
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![BU of 8ptc by Molmil](/molmil-images/mine/8ptc) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5d | 分子名称: | 1,2-ETHANEDIOL, 4-[(3~{R},4~{S})-2-oxidanylidene-3,4-diphenyl-azetidin-1-yl]piperidine-1-carbaldehyde, Monoglyceride lipase | 著者 | Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | 登録日 | 2023-07-14 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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7EXP
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![BU of 7exp by Molmil](/molmil-images/mine/7exp) | Crystal structure of zebrafish TRAP1 with AMPPNP and MitoQ | 分子名称: | 2,3-dimethoxy-5-methyl-6-[10-(triphenyl-$l^{5}-phosphanyl)decyl]cyclohexa-2,5-diene-1,4-dione, COBALT (II) ION, MAGNESIUM ION, ... | 著者 | Lee, H, Yoon, N.G, Kang, B.H, Lee, C. | 登録日 | 2021-05-28 | 公開日 | 2022-01-05 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | 主引用文献 | Mitoquinone Inactivates Mitochondrial Chaperone TRAP1 by Blocking the Client Binding Site. J.Am.Chem.Soc., 143, 2021
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5LI1
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![BU of 5li1 by Molmil](/molmil-images/mine/5li1) | Structure of a Par3-inhibitory peptide bound to PKCiota core kinase domain | 分子名称: | GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Soriano, E.V, Purkiss, A.G, McDonald, N.Q. | 登録日 | 2016-07-13 | 公開日 | 2016-09-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization. Dev.Cell, 38, 2016
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5IKB
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![BU of 5ikb by Molmil](/molmil-images/mine/5ikb) | Crystal structure of the kainate receptor GluK4 ligand binding domain in complex with kainate | 分子名称: | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, GLYCEROL, Glutamate receptor ionotropic, ... | 著者 | Kristensen, O, Kristensen, L.B, Frydenvang, K, Kastrup, J.S. | 登録日 | 2016-03-03 | 公開日 | 2016-08-24 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate. Structure, 24, 2016
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5F9P
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![BU of 5f9p by Molmil](/molmil-images/mine/5f9p) | Crystal structure study of anthrone oxidase-like protein | 分子名称: | Anthrone oxidase-like protein, GLYCEROL | 著者 | Gao, X, Wu, D, Fan, K, Liu, Z.-J. | 登録日 | 2015-12-10 | 公開日 | 2016-12-14 | 最終更新日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (2.078 Å) | 主引用文献 | Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis ACS Chem. Biol., 12, 2017
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6AZM
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![BU of 6azm by Molmil](/molmil-images/mine/6azm) | Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer | 分子名称: | 580 germline antibody, heavy chain, light chain, ... | 著者 | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | 登録日 | 2017-09-11 | 公開日 | 2017-12-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47, 2017
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6V6S
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![BU of 6v6s by Molmil](/molmil-images/mine/6v6s) | Structure of the native human gamma-tubulin ring complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, Gamma-tubulin complex component 2, ... | 著者 | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | 登録日 | 2019-12-05 | 公開日 | 2020-01-01 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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8PTR
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![BU of 8ptr by Molmil](/molmil-images/mine/8ptr) | COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5r | 分子名称: | (3~{R},4~{S})-4-(1,3-benzodioxol-5-yl)-1-[1-(benzotriazol-1-ylcarbonyl)piperidin-4-yl]-3-(3-fluorophenyl)azetidin-2-one, 1,2-ETHANEDIOL, Monoglyceride lipase | 著者 | Butini, S, Benz, J, Grether, U, Leibrock, L, Papa, A, Maramai, S, Carullo, G, Federico, S, Grillo, A, Di Guglielmo, B, Lamponi, S, Gemma, S, Campiani, G. | 登録日 | 2023-07-14 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J.Med.Chem., 67, 2024
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8A9S
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![BU of 8a9s by Molmil](/molmil-images/mine/8a9s) | Crystal structure of Ca2+-discharged obelin in complex with coelenteramine-v | 分子名称: | 3-azanyl-2-(phenylmethyl)benzo[f]quinoxalin-8-ol, DIMETHYL SULFOXIDE, Obelin, ... | 著者 | Kovaleva, M.I, Natashin, P.V, Schevtsov, M.B, Eremeeva, E.V, Bukhdruker, S.S, Dmitrieva, D.A, Mishin, A.V, Vysotski, E.S, Borshchevskiy, V.I. | 登録日 | 2022-06-29 | 公開日 | 2022-10-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of semi-synthetic obelin-v after calcium induced bioluminescence implies coelenteramine as the main reaction product. Sci Rep, 12, 2022
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5LL2
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7ATR
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