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2RF9
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Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
著者Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
登録日2007-09-28
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
1BOB
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BU of 1bob by Molmil
HISTONE ACETYLTRANSFERASE HAT1 FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH ACETYL COENZYME A
分子名称: ACETYL COENZYME *A, CALCIUM ION, HISTONE ACETYLTRANSFERASE
著者Dutnall, R.N, Tafrov, S.T, Sternglanz, R, Ramakrishnan, V.
登録日1998-07-02
公開日1999-04-20
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily.
Cell(Cambridge,Mass.), 94, 1998
4KPW
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Crystal structure of His-tagged human thymidylate synthase R175A mutant
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
著者Pozzi, C, Mangani, S.
登録日2013-05-14
公開日2014-05-14
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Hotspots in an obligate homodimeric anticancer target. Structural and functional effects of interfacial mutations in human thymidylate synthase.
J.Med.Chem., 58, 2015
2XV5
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Human lamin A coil 2B fragment
分子名称: LAMIN-A/C
著者Kapinos, L.E, Burkhard, P, Aebi, U, Herrmann, H, Strelkov, S.V.
登録日2010-10-22
公開日2011-03-09
最終更新日2019-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Simultaneous Formation of Right- and Left-Handed Anti-Parallel Coiled-Coil Interfaces by a Coil2 Fragment of Human Lamin A.
J.Mol.Biol., 408, 2011
5ZND
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BU of 5znd by Molmil
8-mer nanotube derived from 24-mer rHuHF nanocage
分子名称: Ferritin heavy chain
著者Wang, W.M, Wang, L.L, Zang, J.C, Chen, H, Zhao, G.H, Wang, H.F.
登録日2018-04-09
公開日2018-11-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8-mer Nanorings.
J. Am. Chem. Soc., 140, 2018
5OFT
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Structural basis for OXA-48 dimerization
分子名称: Beta-lactamase
著者Lund, B.A, Nesheim, B.H.B, Leiros, H.K.S.
登録日2017-07-11
公開日2018-08-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The biological assembly of OXA-48 reveals a dimer interface with high charge complementarity and very high affinity.
FEBS J., 285, 2018
5E5T
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Quasi-racemic snakin-1 in P1 after radiation damage
分子名称: 1,2-ETHANEDIOL, D- snakin-1, FORMIC ACID, ...
著者Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A.
登録日2015-10-09
公開日2016-05-18
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (1.572 Å)
主引用文献Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
2H2N
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BU of 2h2n by Molmil
Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
分子名称: ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1
著者Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2H2U
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Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
分子名称: CALCIUM ION, Soluble calcium-activated nucleotidase 1
著者Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
登録日2006-05-19
公開日2006-07-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2RFE
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BU of 2rfe by Molmil
Crystal structure of the complex between the EGFR kinase domain and a Mig6 peptide
分子名称: ERBB receptor feedback inhibitor 1, Epidermal growth factor receptor
著者Zhang, X, Pickin, K.A, Bose, R, Jura, N, Cole, P.A, Kuriyan, J.
登録日2007-09-28
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
Nature, 450, 2007
5E5Q
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BU of 5e5q by Molmil
Racemic snakin-1 in P21/c
分子名称: Snakin-1
著者Yeung, H, Squire, C.J, Yosaatmadja, Y, Panjikar, S, Baker, E.N, Harris, P.W.R, Brimble, M.A.
登録日2015-10-09
公開日2016-05-18
最終更新日2016-07-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Radiation Damage and Racemic Protein Crystallography Reveal the Unique Structure of the GASA/Snakin Protein Superfamily.
Angew.Chem.Int.Ed.Engl., 55, 2016
2HIN
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BU of 2hin by Molmil
Structure of N15 Cro at 1.05 A: an ortholog of lambda Cro with a completely different but equally effective dimerization mechanism
分子名称: Repressor protein, SULFATE ION
著者Dubrava, M.S, Ingram, W.M, Roberts, S.A, Weichsel, A, Montfort, W.R, Cordes, M.H.
登録日2006-06-29
公開日2007-07-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献N15 Cro and lambda Cro: orthologous DNA-binding domains with completely different but equally effective homodimer interfaces.
Protein Sci., 17, 2008
1FOA
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BU of 1foa by Molmil
CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
分子名称: ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE, GLYCEROL, MANGANESE (II) ION, ...
著者Unligil, U.M, Zhou, S, Yuwaraj, S, Sarkar, M, Schachter, H, Rini, J.M.
登録日2000-08-26
公開日2001-05-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
1FO9
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CRYSTAL STRUCTURE OF N-ACETYLGLUCOSAMINYLTRANSFERASE I
分子名称: ALPHA-1,3-MANNOSYL-GLYCOPROTEIN BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE
著者Unligil, U.M, Zhou, S, Yuwaraj, S, Sarkar, M, Schachter, H, Rini, J.M.
登録日2000-08-26
公開日2001-04-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献X-ray crystal structure of rabbit N-acetylglucosaminyltransferase I: catalytic mechanism and a new protein superfamily.
EMBO J., 19, 2000
9CPO
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BU of 9cpo by Molmil
Infectious bronchitis virus core polymerase complex
分子名称: Non-structural protein 7, Non-structural protein 8, RNA Primer, ...
著者Hoferle, P.J, Anderson, T.K, Kirchdoerfer, R.N.
登録日2024-07-18
公開日2024-07-31
最終更新日2024-08-14
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A genus-specific nsp12 region impacts polymerase assembly in Alpha- and Gammacoronaviruses.
Biorxiv, 2024
1FXF
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CARBOXYLIC ESTER HYDROLASE COMPLEX (DIMERIC PLA2 + MJ33 INHIBITOR + PHOSPHATE IONS)
分子名称: 1-HEXADECYL-3-TRIFLUOROETHYL-SN-GLYCERO-2-PHOSPHATE METHANE, CALCIUM ION, PHOSPHATE ION, ...
著者Pan, Y.H, Epstein, T.M, Jain, M.K, Bahnson, B.J.
登録日2000-09-25
公開日2001-09-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Five coplanar anion binding sites on one face of phospholipase A2: relationship to interface binding.
Biochemistry, 40, 2001
1QAC
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BU of 1qac by Molmil
CHANGE IN DIMERIZATION MODE BY REMOVAL OF A SINGLE UNSATISFIED POLAR RESIDUE
分子名称: IMMUNOGLOBULIN LIGHT CHAIN VARIABLE DOMAIN
著者Pokkuluri, P.R, Cai, X, Johnson, G, Stevens, F.J, Schiffer, M.
登録日1999-02-25
公開日2000-02-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Change in dimerization mode by removal of a single unsatisfied polar residue located at the interface.
Protein Sci., 9, 2000
4D7R
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BU of 4d7r by Molmil
Crystal structure of a chimeric protein with the Sec7 domain of Rickettsia prowazekii RalF and the capping domain of Legionella pneumophila RalF
分子名称: PROLINE/BETAINE TRANSPORTER, RALF
著者Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V.
登録日2014-11-27
公開日2015-01-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
4D7Q
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Crystal structure of a chimeric protein with the Sec7 domain of Legionella pneumophila RalF and the capping domain of Rickettsia prowazekii RalF
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Folly-Klan, M, Sancerne, B, Alix, E, Roy, C.R, Cherfils, J, Campanacci, V.
登録日2014-11-27
公開日2015-01-14
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献On the Use of Legionella/Rickettsia Chimeras to Investigate the Structure and Regulation of Rickettsia Effector Ralf.
J.Struct.Biol., 189, 2015
1OIJ
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Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with alphaketoglutarate
分子名称: 2-OXOGLUTARIC ACID, PUTATIVE ALKYLSULFATASE ATSK, SODIUM ION
著者Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I.
登録日2003-06-18
公開日2004-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily
Biochemistry, 42, 2004
1OIK
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Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with fe, alphaketoglutarate and 2-ethyl-1-hexanesulfuric acid
分子名称: (2R)-2-ETHYL-1-HEXANESULFONIC ACID, 2-OXOGLUTARIC ACID, FE (II) ION, ...
著者Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I.
登録日2003-06-18
公開日2004-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily
Biochemistry, 42, 2004
1OII
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Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with iron and alphaketoglutarate
分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, PUTATIVE ALKYLSULFATASE ATSK
著者Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I.
登録日2003-06-18
公開日2004-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily
Biochemistry, 42, 2004
6DJ1
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Wild-type HIV-1 protease in complex with Lopinavir
分子名称: CHLORIDE ION, HIV-1 protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, ...
著者Wang, Y.-F, Wong-Sam, A.E, Zhang, Y, Weber, I.T.
登録日2018-05-24
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease.
ACS Omega, 3, 2018
6DJ7
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HIV-1 protease with mutation L76V in complex with GRL-5010 (gem-difluoro-bis-tetrahydrofuran as P2 ligand)
分子名称: (3R,3aS,6aS)-4,4-difluorohexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, ACETATE ION, CHLORIDE ION, ...
著者Wong-Sam, A.E, Wang, Y.F, Weber, I.T.
登録日2018-05-24
公開日2018-10-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Drug Resistance Mutation L76V Alters Nonpolar Interactions at the Flap-Core Interface of HIV-1 Protease.
ACS Omega, 3, 2018
1E3O
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Crystal structure of Oct-1 POU dimer bound to MORE
分子名称: 5'-D(*AP*TP*GP*CP*AP*TP*GP*AP*GP*GP*A)-3', 5'-D(*TP*CP*CP*TP*CP*AP*TP*GP*CP*AP*T)-3', OCTAMER-BINDING TRANSCRIPTION FACTOR 1
著者Remenyi, A, Tomilin, A, Pohl, E, Schoeler, H, Wilmanns, M.
登録日2000-06-20
公開日2001-11-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Mol.Cell, 8, 2001

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