6WC8
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6WKU
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![BU of 6wku by Molmil](/molmil-images/mine/6wku) | Twelve Chloride Ions Drive Assembly of Human alpha345 Collagen IV NC1 domain | 分子名称: | 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... | 著者 | Boudko, S.P, Hudson, B.G. | 登録日 | 2020-04-17 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Collagen IV alpha 345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the alpha 345 hexamer. J.Biol.Chem., 296, 2021
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6WZW
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![BU of 6wzw by Molmil](/molmil-images/mine/6wzw) | Ash1L SET domain in complex with AS-85 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histone-lysine N-methyltransferase ASH1L, N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl)sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide, ... | 著者 | Li, H, Deng, J, Cierpicki, T, Grembecka, J. | 登録日 | 2020-05-14 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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6X0P
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![BU of 6x0p by Molmil](/molmil-images/mine/6x0p) | Ash1L SET domain Q2265A mutant in complex with AS-5 | 分子名称: | 3-[6-(aminomethyl)-1-(2-hydroxyethyl)-1H-indol-3-yl]benzene-1-carbothioamide, Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ... | 著者 | Rogawski, D.S, Li, H, Borkin, D, Cierpicki, T, Grembecka, J. | 登録日 | 2020-05-17 | 公開日 | 2021-04-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
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6WMZ
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6WH6
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![BU of 6wh6 by Molmil](/molmil-images/mine/6wh6) | Crystal structure of human sulfide quinone oxidoreductase in complex with coenzyme Q (cyanide soaked) | 分子名称: | CYANIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Sulfide:quinone oxidoreductase, ... | 著者 | Banerjee, R, Cho, U.S, Moon, S. | 登録日 | 2020-04-07 | 公開日 | 2021-04-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Dismantling and Rebuilding the Trisulfide Cofactor Demonstrates Its Essential Role in Human Sulfide Quinone Oxidoreductase. J.Am.Chem.Soc., 142, 2020
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6WNK
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![BU of 6wnk by Molmil](/molmil-images/mine/6wnk) | Macrocyclic peptides TDI5575 that selectively inhibit the Mycobacterium tuberculosis proteasome | 分子名称: | (12S,15S)-N-[(2-fluorophenyl)methyl]-10,13-dioxo-12-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}-2-oxa-11,14-diazatricyclo[15.2.2.1~3,7~]docosa-1(19),3(22),4,6,17,20-hexaene-15-carboxamide, CITRIC ACID, DIMETHYLFORMAMIDE, ... | 著者 | Hsu, H.C, Li, H. | 登録日 | 2020-04-22 | 公開日 | 2021-04-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome. J.Med.Chem., 64, 2021
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6WHG
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![BU of 6whg by Molmil](/molmil-images/mine/6whg) | PI3P and calcium bound full-length TRPY1 in detergent | 分子名称: | (2R)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2S,3S,4S,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl hexadecanoate, CALCIUM ION, Calcium channel YVC1 | 著者 | Ahmed, T, Moiseenkova-Bell, V.Y. | 登録日 | 2020-04-08 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Structure, 30, 2022
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6WM8
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2APF
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![BU of 2apf by Molmil](/molmil-images/mine/2apf) | Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain | 分子名称: | MALONIC ACID, T cell receptor beta chain V | 著者 | Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. | 登録日 | 2005-08-16 | 公開日 | 2006-03-21 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
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6WJZ
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6WKT
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6WTA
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6WSH
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6WKN
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![BU of 6wkn by Molmil](/molmil-images/mine/6wkn) | PL-bound rat TRPV2 in nanodiscs | 分子名称: | Transient receptor potential cation channel subfamily V member 2, piperlongumine | 著者 | Pumroy, R.P, Moiseenkova-Bell, V.Y. | 登録日 | 2020-04-16 | 公開日 | 2021-04-21 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Acs Cent.Sci., 7, 2021
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6WR1
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![BU of 6wr1 by Molmil](/molmil-images/mine/6wr1) | Human steroidogenic cytochrome P450 17A1 mutant N52Y with inhibitor abiraterone | 分子名称: | Abiraterone, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase | 著者 | Petrunak, E.M, Bart, A.G, Scott, E.E. | 登録日 | 2020-04-29 | 公開日 | 2021-05-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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2B00
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![BU of 2b00 by Molmil](/molmil-images/mine/2b00) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate | 分子名称: | CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ... | 著者 | Pan, Y.H, Bahnson, B.J, Jain, M.K. | 登録日 | 2005-09-12 | 公開日 | 2006-11-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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2B04
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![BU of 2b04 by Molmil](/molmil-images/mine/2b04) | Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ... | 著者 | Pan, Y.H, Bahnson, B.J, Jain, M.K. | 登録日 | 2005-09-12 | 公開日 | 2006-11-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
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2AUB
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![BU of 2aub by Molmil](/molmil-images/mine/2aub) | Lysozyme structure derived from thin-film-based crystals | 分子名称: | Lysozyme C | 著者 | Pechkova, E, Sivozhelezov, V, Tropiano, G, Fiordoro, S, Nicolini, C. | 登録日 | 2005-08-27 | 公開日 | 2005-12-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Comparison of lysozyme structures derived from thin-film-based and classical crystals. Acta Crystallogr.,Sect.D, 61, 2005
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6WTB
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![BU of 6wtb by Molmil](/molmil-images/mine/6wtb) | Sort-Tagged Drosophila Cryptochrome | 分子名称: | Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION | 著者 | Schneps, C.M, Crane, B.R. | 登録日 | 2020-05-02 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol, 4, 2021
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6WR0
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![BU of 6wr0 by Molmil](/molmil-images/mine/6wr0) | Human steroidogenic cytochrome P450 17A1 with 3-keto-delta4-abiraterone analog | 分子名称: | (8alpha)-17-(pyridin-3-yl)androsta-4,16-dien-3-one, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Petrunak, E.M, Bart, A.G, Scott, E.E. | 登録日 | 2020-04-29 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
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6WXI
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![BU of 6wxi by Molmil](/molmil-images/mine/6wxi) | Colicin E1 fragment in nanodisc-embedded TolC | 分子名称: | Outer membrane protein TolC | 著者 | Kaelber, J.T, Budiardjo, S.J, Firlar, E, Ikujuni, A.P, Slusky, J.S.G. | 登録日 | 2020-05-10 | 公開日 | 2021-05-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Colicin E1 opens its hinge to plug TolC. Elife, 11, 2022
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6WXH
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![BU of 6wxh by Molmil](/molmil-images/mine/6wxh) | Colicin E1 fragment in nanodisc-embedded TolC | 分子名称: | Colicin-E1, Outer membrane protein TolC | 著者 | Kaelber, J.T, Budiardjo, S.J, Firlar, E, Case, D.A, Ikujuni, A.P, Slusky, J.S.G. | 登録日 | 2020-05-10 | 公開日 | 2021-05-12 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Colicin E1 opens its hinge to plug TolC. Elife, 11, 2022
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2AHU
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![BU of 2ahu by Molmil](/molmil-images/mine/2ahu) | Crystal structure of Acyl-CoA transferase (YdiF) apoenzyme from Escherichia coli O157:H7. | 分子名称: | putative enzyme ydiF | 著者 | Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2005-07-28 | 公開日 | 2005-11-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases. J.Biol.Chem., 280, 2005
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2B20
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![BU of 2b20 by Molmil](/molmil-images/mine/2b20) | Crystal Structure of Enterochelin Esterase from Shigella flexneri Enterochelin Esterase | 分子名称: | L(+)-TARTARIC ACID, enterochelin esterase | 著者 | Kim, Y, Maltseva, N, Dementieva, I, Quartey, P, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2005-09-16 | 公開日 | 2005-11-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal Structure of Enterochelin Esterase from Shigella flexneri
Enterochelin Esterase To be Published
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