PDB: 223790 件ウェブページステータス検索Chemie searchBIRD

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6WC8	HIV Integrase core domain in complex with inhibitor 2-(5-(3-fluorophenyl)-2-(2-(thiophen-2-yl)ethynyl)-1- benzofuran-3-yl)ethanoic acid 分子名称: IODIDE ION, Integrase, SULFATE ION, ... 著者 Gorman, M.A, Parker, M.W. 登録日 2020-03-29 公開日 2021-03-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 HIV Integrase core domain in complex with inhibitor To Be Published
6WKU	Twelve Chloride Ions Drive Assembly of Human alpha345 Collagen IV NC1 domain 分子名称: 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CHLORIDE ION, ... 著者 Boudko, S.P, Hudson, B.G. 登録日 2020-04-17 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Collagen IV alpha 345 dysfunction in glomerular basement membrane diseases. II. Crystal structure of the alpha 345 hexamer. J.Biol.Chem., 296, 2021
6WZW	Ash1L SET domain in complex with AS-85 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Histone-lysine N-methyltransferase ASH1L, N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl)sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide, ... 著者 Li, H, Deng, J, Cierpicki, T, Grembecka, J. 登録日 2020-05-14 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
6X0P	Ash1L SET domain Q2265A mutant in complex with AS-5 分子名称: 3-[6-(aminomethyl)-1-(2-hydroxyethyl)-1H-indol-3-yl]benzene-1-carbothioamide, Histone-lysine N-methyltransferase ASH1L, S-ADENOSYLMETHIONINE, ... 著者 Rogawski, D.S, Li, H, Borkin, D, Cierpicki, T, Grembecka, J. 登録日 2020-05-17 公開日 2021-04-07 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity. Nat Commun, 12, 2021
6WMZ	Crystal structure of human SFPQ/NONO complex 分子名称: Non-POU domain-containing octamer-binding protein, SULFATE ION, Splicing factor, ... 著者 Lee, M, Bond, C.S. 登録日 2020-04-22 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure analysis of human SFPQ/NONO complex To Be Published
6WH6	Crystal structure of human sulfide quinone oxidoreductase in complex with coenzyme Q (cyanide soaked) 分子名称: CYANIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Sulfide:quinone oxidoreductase, ... 著者 Banerjee, R, Cho, U.S, Moon, S. 登録日 2020-04-07 公開日 2021-04-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Dismantling and Rebuilding the Trisulfide Cofactor Demonstrates Its Essential Role in Human Sulfide Quinone Oxidoreductase. J.Am.Chem.Soc., 142, 2020
6WNK	Macrocyclic peptides TDI5575 that selectively inhibit the Mycobacterium tuberculosis proteasome 分子名称: (12S,15S)-N-[(2-fluorophenyl)methyl]-10,13-dioxo-12-{2-oxo-2-[(2R)-2-phenylpyrrolidin-1-yl]ethyl}-2-oxa-11,14-diazatricyclo[15.2.2.1~3,7~]docosa-1(19),3(22),4,6,17,20-hexaene-15-carboxamide, CITRIC ACID, DIMETHYLFORMAMIDE, ... 著者 Hsu, H.C, Li, H. 登録日 2020-04-22 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Macrocyclic Peptides that Selectively Inhibit the Mycobacterium tuberculosis Proteasome. J.Med.Chem., 64, 2021
6WHG	PI3P and calcium bound full-length TRPY1 in detergent 分子名称: (2R)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2S,3S,4S,5S,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propan-2-yl hexadecanoate, CALCIUM ION, Calcium channel YVC1 著者 Ahmed, T, Moiseenkova-Bell, V.Y. 登録日 2020-04-08 公開日 2021-04-21 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structure of the ancient TRPY1 channel from Saccharomyces cerevisiae reveals mechanisms of modulation by lipids and calcium. Structure, 30, 2022
6WM8	Proliferation-Associated protein 2G4 (PA2G4) 分子名称: Proliferation-associated protein 2G4, SULFATE ION 著者 Gorman, M.A, Stevenson, B.W, Parker, M.W. 登録日 2020-04-20 公開日 2021-04-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 PA2G4: A Structural Perspective To Be Published
2APF	Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain 分子名称: MALONIC ACID, T cell receptor beta chain V 著者 Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J. 登録日 2005-08-16 公開日 2006-03-21 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction. Structure, 13, 2005
6WJZ	Crystal structure of human ribokinase in complex with AMPCP 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... 著者 Park, J. 登録日 2020-04-15 公開日 2021-04-21 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structures of human ribokinase To Be Published
6WKT	Cu(I)-bound Copper Storage Protein BsCsp3 分子名称: Csp3 著者 Chen, J.Z, Oken, A, Dennison, C, Lee, J, David, S. 登録日 2020-04-16 公開日 2021-04-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cu(I)-bound Copper Storage Protein BsCsp3 To Be Published
6WTA	Structure of F420-H2 Dependent Oxidoreductase (FDOR-A) MSMEG_2027 in complex with F420 分子名称: COENZYME F420-4, Uncharacterized protein 著者 Jackson, C.J, Antoney, J.P. 登録日 2020-05-01 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 A F420-dependent single domain chemogenetic tool for protein de-dimerization Biorxiv, 2022
6WSH	Crystal structure of EutV from Enterococcus faecalis 分子名称: GLYCEROL, MAGNESIUM ION, Response regulator, ... 著者 Ataide, S.F, Walshe, J.L. 登録日 2020-05-01 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural characterization of the ANTAR antiterminator domain bound to RNA. Nucleic Acids Res., 50, 2022
6WKN	PL-bound rat TRPV2 in nanodiscs 分子名称: Transient receptor potential cation channel subfamily V member 2, piperlongumine 著者 Pumroy, R.P, Moiseenkova-Bell, V.Y. 登録日 2020-04-16 公開日 2021-04-21 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression. Acs Cent.Sci., 7, 2021
6WR1	Human steroidogenic cytochrome P450 17A1 mutant N52Y with inhibitor abiraterone 分子名称: Abiraterone, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase 著者 Petrunak, E.M, Bart, A.G, Scott, E.E. 登録日 2020-04-29 公開日 2021-05-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
2B00	Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycocholate 分子名称: CALCIUM ION, GLYCOCHOLIC ACID, Phospholipase A2, ... 著者 Pan, Y.H, Bahnson, B.J, Jain, M.K. 登録日 2005-09-12 公開日 2006-11-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
2B04	Crystal Structure of Porcine Pancreatic Phospholipase A2 in Complex with Glycochenodeoxycholate 分子名称: CALCIUM ION, CHLORIDE ION, GLYCOCHENODEOXYCHOLIC ACID, ... 著者 Pan, Y.H, Bahnson, B.J, Jain, M.K. 登録日 2005-09-12 公開日 2006-11-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for bile salt inhibition of pancreatic phospholipase A2. J.Mol.Biol., 369, 2007
2AUB	Lysozyme structure derived from thin-film-based crystals 分子名称: Lysozyme C 著者 Pechkova, E, Sivozhelezov, V, Tropiano, G, Fiordoro, S, Nicolini, C. 登録日 2005-08-27 公開日 2005-12-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Comparison of lysozyme structures derived from thin-film-based and classical crystals. Acta Crystallogr.,Sect.D, 61, 2005
6WTB	Sort-Tagged Drosophila Cryptochrome 分子名称: Cryptochrome-1, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION 著者 Schneps, C.M, Crane, B.R. 登録日 2020-05-02 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Tuning flavin environment to detect and control light-induced conformational switching in Drosophila cryptochrome. Commun Biol, 4, 2021
6WR0	Human steroidogenic cytochrome P450 17A1 with 3-keto-delta4-abiraterone analog 分子名称: (8alpha)-17-(pyridin-3-yl)androsta-4,16-dien-3-one, CHLORIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Petrunak, E.M, Bart, A.G, Scott, E.E. 登録日 2020-04-29 公開日 2021-05-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Human cytochrome P450 17A1 structures with metabolites of prostate cancer drug abiraterone reveal substrate-binding plasticity and a second binding site. J.Biol.Chem., 299, 2023
6WXI	Colicin E1 fragment in nanodisc-embedded TolC 分子名称: Outer membrane protein TolC 著者 Kaelber, J.T, Budiardjo, S.J, Firlar, E, Ikujuni, A.P, Slusky, J.S.G. 登録日 2020-05-10 公開日 2021-05-12 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Colicin E1 opens its hinge to plug TolC. Elife, 11, 2022
6WXH	Colicin E1 fragment in nanodisc-embedded TolC 分子名称: Colicin-E1, Outer membrane protein TolC 著者 Kaelber, J.T, Budiardjo, S.J, Firlar, E, Case, D.A, Ikujuni, A.P, Slusky, J.S.G. 登録日 2020-05-10 公開日 2021-05-12 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Colicin E1 opens its hinge to plug TolC. Elife, 11, 2022
2AHU	Crystal structure of Acyl-CoA transferase (YdiF) apoenzyme from Escherichia coli O157:H7. 分子名称: putative enzyme ydiF 著者 Rangarajan, E.S, Li, Y, Ajamian, E, Iannuzzi, P, Kernaghan, S.D, Fraser, M.E, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) 登録日 2005-07-28 公開日 2005-11-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases. J.Biol.Chem., 280, 2005
2B20	Crystal Structure of Enterochelin Esterase from Shigella flexneri Enterochelin Esterase 分子名称: L(+)-TARTARIC ACID, enterochelin esterase 著者 Kim, Y, Maltseva, N, Dementieva, I, Quartey, P, Holzle, D, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2005-09-16 公開日 2005-11-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal Structure of Enterochelin Esterase from Shigella flexneri Enterochelin Esterase To be Published

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