PDB: 98225 件ウェブページステータス検索Chemie searchBIRD

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8D47	fp.006 Fab in complex with SARS-CoV-2 Fusion Peptide 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... 著者 Abernathy, M.E, Barnes, C.O. 登録日 2022-06-01 公開日 2022-12-21 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Human neutralizing antibodies to cold linear epitopes and subdomain 1 of the SARS-CoV-2 spike glycoprotein. Sci Immunol, 8, 2023
2DSQ	Structural Basis for the Inhibition of Insulin-like Growth Factors by IGF Binding Proteins 分子名称: Insulin-like growth factor IB, Insulin-like growth factor-binding protein 1, Insulin-like growth factor-binding protein 4 著者 Sitar, T, Popowicz, G.M, Siwanowicz, I, Huber, R, Holak, T.A. 登録日 2006-07-05 公開日 2006-08-22 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc.Natl.Acad.Sci.Usa, 103, 2006
8B0R	Structure of the CalpL/cA4 complex 分子名称: Cyclic tetraadenosine monophosphate (cA4), SMODS-associated and fused to various effectors domain-containing protein, SULFATE ION, ... 著者 Schneberger, N, Hagelueken, G. 登録日 2022-09-08 公開日 2022-11-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Antiviral signalling by a cyclic nucleotide activated CRISPR protease. Nature, 614, 2023
1CP4	FORMATION, CRYSTAL STRUCTURE, AND REARRANGEMENT OF A CYTOCHROME P450-CAM IRON-PHENYL COMPLEX 分子名称: BENZENE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Raag, R, Poulos, T.L. 登録日 1991-06-04 公開日 1993-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Formation, crystal structure, and rearrangement of a cytochrome P-450cam iron-phenyl complex. Biochemistry, 29, 1990
6ZD9	Crystal structure of YTHDC1 apo purified using GST tag 分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTHDC1 著者 Bedi, R.K, Caflisch, A. 登録日 2020-06-14 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
8AMG	Crystal structure of AUGUGGCAU duplex with barium ions (model 1) 分子名称: BARIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
8AMM	Crystal structure of AUGUGGCAU duplex with cesium ions 分子名称: CESIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.86 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
8AMJ	Crystal structure of unliganded AUGUGGCAU duplex 分子名称: ACETATE ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), SULFATE ION 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
7LB8	Structure of a ferrichrome importer FhuCDB from E. coli 分子名称: Iron(3+)-hydroxamate import ATP-binding protein FhuC, Iron(3+)-hydroxamate import system permease protein FhuB, Iron(3+)-hydroxamate-binding protein FhuD 著者 Hu, W, Zheng, H. 登録日 2021-01-07 公開日 2021-11-24 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Cryo-EM reveals unique structural features of the FhuCDB Escherichia coli ferrichrome importer. Commun Biol, 4, 2021
8AMI	Crystal structure of AUGUGGCAU duplex with barium ions (model 2) 分子名称: BARIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), SODIUM ION 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
8AML	Crystal structure of AUGUGGCAU duplex with cadmium ions 分子名称: CADMIUM ION, RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
8AMK	Crystal structure of AUGUGGCAU duplex crystallized in the presence of calcium ions 分子名称: RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3') 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
8AMN	Crystal structure of AUGUGGCAU duplex with strontium ions 分子名称: RNA (5'-R(*AP*UP*GP*UP*GP*GP*CP*AP*U)-3'), STRONTIUM ION 著者 Kiliszek, A, Rypniewski, W. 登録日 2022-08-03 公開日 2022-11-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Structure and thermodynamics of a UGG motif interacting with Ba2+ and other metal ions: accommodating changes in the RNA structure and the presence of a G(syn)-G(syn) pair. Rna, 29, 2022
7LO9	RNA dodecamer containing a GNA A residue 分子名称: Chains: A,B,C,D 著者 Harp, J.M, Wawrzak, Z, Egli, M. 登録日 2021-02-09 公開日 2021-12-22 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs. Nucleic Acids Res., 49, 2021
6ZD7	Crystal structure of YTHDC1 T379V mutant complex with m6A 分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1 著者 Bedi, R.K, Li, Y, Caflisch, A. 登録日 2020-06-13 公開日 2021-01-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
7LUH	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment bromophenoxy propanamide 分子名称: (2~{R})-2-(4-bromanylphenoxy)propanamide, Thiol:disulfide interchange protein 著者 Petit, G.A, Martin, J.L, McMahon, R.M. 登録日 2021-02-22 公開日 2022-01-05 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LUJ	Burkholderia pseudomallei Disulfide bond forming protein A (DsbA) liganded with fragment 4-methoxy-N-phenylbenzenesulfonamide 分子名称: 4-methoxy-~{N}-phenyl-benzenesulfonamide, SULFATE ION, Thiol:disulfide interchange protein 著者 Petit, G.A, Martin, J.L, McMahon, R.M. 登録日 2021-02-22 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Identification and characterization of two drug-like fragments that bind to the same cryptic binding pocket of Burkholderia pseudomallei DsbA. Acta Crystallogr D Struct Biol, 78, 2022
7LVZ	Crystal structure of ADO 分子名称: 2-aminoethanethiol dioxygenase, CHLORIDE ION, FE (II) ION, ... 著者 Bingman, C.A, Fernandez, R.L, Smith, R.W, Fox, B.G, Brunold, T.C. 登録日 2021-02-26 公開日 2022-01-05 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 The Crystal Structure of Cysteamine Dioxygenase Reveals the Origin of the Large Substrate Scope of This Vital Mammalian Enzyme. Biochemistry, 60, 2021
7LCU	X-ray structure of Furin bound to BOS-318, a small molecule inhibitor 分子名称: (1-{[2-(3,5-dichlorophenyl)-6-{[2-(4-methylpiperazin-1-yl)pyrimidin-5-yl]oxy}pyridin-4-yl]methyl}piperidin-4-yl)acetic acid, 1,2-ETHANEDIOL, CALCIUM ION, ... 著者 Campobasso, N, Reid, R. 登録日 2021-01-11 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.24 Å) 主引用文献 A highly selective, cell-permeable furin inhibitor BOS-318 rescues key features of cystic fibrosis airway disease. Cell Chem Biol, 29, 2022
7LTY	Bruton's tyrosine kinase in complex with compound 23 分子名称: DIMETHYL SULFOXIDE, Isoform BTK-C of Tyrosine-protein kinase BTK, ~{N}-[(5~{R})-2-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-6,7,8,9-tetrahydro-5~{H}-benzo[7]annulen-5-yl]-3-propan-2-yloxy-azetidine-1-carboxamide 著者 Metrick, C.M, Marcotte, D.J. 登録日 2021-02-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 65, 2022
7LTZ	Bruton's tyrosine kinase in complex with compound 51 分子名称: 1-~{tert}-butyl-~{N}-[(5~{R})-8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]-1,2,3-triazole-4-carboxamide, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ACETATE ION, ... 著者 Metrick, C.M, Marcotte, D.J. 登録日 2021-02-20 公開日 2022-01-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis. J.Med.Chem., 65, 2022
8DB3	Crystal structure of KaiC with truncated C-terminal coiled-coil domain 分子名称: ADENOSINE-5'-DIPHOSPHATE, Circadian clock protein KaiC 著者 Padua, R.A.P, Grant, T, Pitsawong, W, Hoemberger, M.S, Otten, R, Bradshaw, N, Grigorieff, N, Kern, D. 登録日 2022-06-14 公開日 2023-03-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 From primordial clocks to circadian oscillators. Nature, 616, 2023
6Z00	Arabidopsis thaliana Naa50 in complex with bisubstrate analogue CoA-Ac-MVNAL 分子名称: Acyl-CoA N-acyltransferases (NAT) superfamily protein, CARBOXYMETHYL COENZYME *A, MET-VAL-ASN-ALA-LEU 著者 Weidenhausen, J, Kopp, J, Lapouge, K, Sinning, I. 登録日 2020-05-07 公開日 2020-12-30 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Structural and functional characterization of the N-terminal acetyltransferase Naa50. Structure, 29, 2021
7QHP	Structure of I-Ag7 with a bound hybrid insulin peptide 分子名称: GLYCEROL, H-2 class II histocompatibility antigen, A-D alpha chain, ... 著者 Lopez-Sagaseta, J, Erausquin, E. 登録日 2021-12-13 公開日 2022-07-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes. Front Immunol, 13, 2022
7QQR	SpCas9 bound to AAVS1 off-target5 DNA substrate 分子名称: 1,2-ETHANEDIOL, AAVS1 off-target5 non-target strand, AAVS1 off-target5 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022

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