PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3TPJ	APO structure of BACE1 分子名称: Beta-secretase 1, CHLORIDE ION, SULFATE ION, ... 著者 Xu, Y.C, Li, M.J, Greenblatt, H, Chen, T.T, Silman, I, Sussman, J.L. 登録日 2011-09-08 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations Acta Crystallogr.,Sect.D, 68, 2012
3TQU	Structure of a HAM1 protein from Coxiella burnetii 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Non-canonical purine NTP pyrophosphatase 著者 Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-09-09 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
3U7F	Crystal structure of mPNKP catalytic fragment (D170A) bound to single-stranded DNA (TCCTCp) 分子名称: Bifunctional polynucleotide phosphatase/kinase, DNA, GLYCEROL, ... 著者 Coquelle, N, Havali, Z, Bernstein, N, Green, R, Glover, J.N.M. 登録日 2011-10-13 公開日 2011-12-14 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for the phosphatase activity of polynucleotide kinase/phosphatase on single- and double-stranded DNA substrates. Proc.Natl.Acad.Sci.USA, 108, 2011
3TRZ	Mouse Lin28A in complex with let-7d microRNA pre-element 分子名称: Protein lin-28 homolog A, RNA (5'-R(*GP*GP*GP*CP*AP*GP*GP*GP*AP*UP*UP*UP*UP*GP*CP*CP*CP*GP*GP*AP*G)-3'), ZINC ION 著者 Nam, Y, Sliz, P. 登録日 2011-09-11 公開日 2011-11-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Molecular Basis for Interaction of let-7 MicroRNAs with Lin28. Cell(Cambridge,Mass.), 147, 2011
3TV2	Structure of a class II fumarate hydratase from Burkholderia pseudomallei 分子名称: Fumarate hydratase, class II, SODIUM ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-09-19 公開日 2011-09-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of a class II fumarate hydratase from Burkholderia pseudomallei To be Published
3U9P	Crystal Structure of Murine Siderocalin in Complex with an Fab Fragment 分子名称: Monoclonal Fab Fragment Heavy Chain, Monoclonal Fab Fragment Light Chain, Neutrophil gelatinase-associated lipocalin 著者 Correnti, C, Strong, R.K. 登録日 2011-10-19 公開日 2013-05-01 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Siderocalin/Lcn2/NGAL/24p3 does not drive apoptosis through gentisic acid mediated iron withdrawal in hematopoietic cell lines. Plos One, 7, 2012
3TYZ	Crystal Structure of the Yersinia pestis Dihydropteroate synthetase with substrate transition state complex. 分子名称: 2-amino-6-methylidene-6,7-dihydropteridin-4(3H)-one, 4-AMINOBENZOIC ACID, 7,8-dihydropteroate synthase, ... 著者 Wu, Y. 登録日 2011-09-26 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335, 2012
3TZB	Quinone Oxidoreductase (NQ02) bound to NSC13000 分子名称: 9-AMINOACRIDINE, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Dunstan, M.S, Leys, D. 登録日 2011-09-27 公開日 2011-11-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.1901 Å) 主引用文献 In silico screening reveals structurally diverse, nanomolar inhibitors of NQO2 that are functionally active in cells and can modulate NF-kappa B signaling. Mol.Cancer Ther., 11, 2012
3UAY	Crystal structure of Bacillus cereus adenosine phosphorylase D204N mutant complexed with adenosine 分子名称: ADENOSINE, GLYCEROL, Purine nucleoside phosphorylase deoD-type, ... 著者 Dessanti, P, Zhang, Y, Allegrini, S, Tozzi, M.G, Sgarrella, F, Ealick, S.E. 登録日 2011-10-22 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase. Acta Crystallogr.,Sect.D, 68, 2012
3WNR	Multiple binding modes of benzyl isothiocyanate inhibitor complexed with Macrophage Migration Inhibitory Factor 分子名称: CHLORIDE ION, GLYCEROL, Macrophage migration inhibitory factor, ... 著者 Spencer, E.S, Dale, E.J, Gommans, A.L, Rutledge, M.T, Gamble, A.B, Smith, R.A.J, Wilbanks, S.M, Hampton, M.B, Tyndall, J.D.A. 登録日 2013-12-16 公開日 2014-03-05 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.008 Å) 主引用文献 Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor Eur.J.Med.Chem., 93, 2015
3W40	Crystal structure of RsbX in complex with magnesium in space group P1 分子名称: MAGNESIUM ION, Phosphoserine phosphatase RsbX 著者 Teh, A.H, Makino, M, Baba, S, Shimizu, N, Yamamoto, M, Kumasaka, T. 登録日 2013-01-04 公開日 2014-01-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure of the RsbX phosphatase involved in the general stress response of Bacillus subtilis Acta Crystallogr.,Sect.D, 71, 2015
3UCL	Cyclohexanone-bound crystal structure of cyclohexanone monooxygenase in the Rotated conformation 分子名称: CYCLOHEXANONE, Cyclohexanone monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Yachnin, B.J, Berghuis, A.M. 登録日 2011-10-27 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 The Substrate-Bound Crystal Structure of a Baeyer-Villiger Monooxygenase Exhibits a Criegee-like Conformation. J.Am.Chem.Soc., 134, 2012
3UDK	Crystal Structure of BACE with Compound 6 分子名称: 1,2-ETHANEDIOL, Beta-secretase 1, DI(HYDROXYETHYL)ETHER, ... 著者 Efremov, I.V, Vajdos, F.F, Borzilleri, K, Capetta, S, Dorff, P, Dutra, J, Mansour, M, Oborski, C, O'Connell, T, O'Sullivan, T.J, Pandit, J, Wang, H, Withka, J. 登録日 2011-10-28 公開日 2012-04-18 最終更新日 2018-04-04 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Discovery and optimization of a novel spiropyrrolidine inhibitor of {beta}-secretase (BACE1) through fragment-based drug design. J.Med.Chem., 55, 2012
3UJ2	CRYSTAL STRUCTURE OF AN ENOLASE FROM ANAEROSTIPES CACCAE (EFI TARGET EFI-502054) WITH BOUND MG AND SULFATE 分子名称: Enolase 1, MAGNESIUM ION, SULFATE ION 著者 Vetting, M.W, Toro, R, Bhosle, R, Hillerich, B, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) 登録日 2011-11-07 公開日 2011-11-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CRYSTAL STRUCTURE OF AN ENOLASE FROM ANAEROSTIPES CACCAE (EFI TARGET EFI-502054) WITH BOUND MG AND SULFATE to be published
3UL3	Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery 分子名称: Thioredoxin 著者 Sharma, A, Sharma, A, Dixit, S, Sharma, A. 登録日 2011-11-10 公開日 2011-12-14 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.905 Å) 主引用文献 Structural insights into thioredoxin-2: a component of malaria parasite protein secretion machinery. Sci Rep, 1, 2011
3UC2	Crystal structure of a DUF4426 family protein (PA0388) from Pseudomonas aeruginosa PAO1 at 2.09 A resolution 分子名称: GLYCEROL, SULFATE ION, hypothetical protein with immunoglobulin-like fold 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-10-25 公開日 2011-11-23 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Crystal structure of a hypothetical protein with immunoglobulin-like fold (PA0388) from Pseudomonas aeruginosa PAO1 at 2.09 A resolution To be published
3UCG	Crystal structure of a RNA binding domain of polyadenylate-binding protein (PABPN1) from Homo sapiens at 1.95 A resolution 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Polyadenylate-binding protein 2, ... 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-10-26 公開日 2011-11-23 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of a RNA binding domain of Hypothetical POLYADENYLATE-BINDING PROTEIN (PABPN1) from Homo sapiens at 1.95 A resolution To be published
3UFM	Co-crystal structure of Deinococcus radiodurans uracil-DNA glycosylase and the C-terminus of the single-stranded DNA-binding protein 分子名称: IODIDE ION, Single-stranded DNA-binding protein, Uracil-DNA glycosylase 著者 George, N.P, Keck, J.L. 登録日 2011-11-01 公開日 2012-11-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Identification of the SSB-interaction platform of Deinococcus radiodurans uracil-DNA glycosylase To be Published
3UIF	CRYSTAL STRUCTURE OF putative sulfonate ABC transporter, periplasmic sulfonate-binding protein SsuA from Methylobacillus flagellatus KT 分子名称: GLYCEROL, SULFATE ION, Sulfonate ABC transporter, ... 著者 Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2011-11-04 公開日 2011-11-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 CRYSTAL STRUCTURE OF putative sulfonate ABC transporter, periplasmic sulfonate-binding protein SsuA from Methylobacillus flagellatus KT To be Published
3UIO	Complex between human RanGAP1-SUMO2, UBC9 and the IR1 domain from RanBP2 containing IR2 Motif II 分子名称: E3 SUMO-protein ligase RanBP2, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... 著者 Gareau, J.R, Reverter, D, Lima, C.D. 登録日 2011-11-05 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.602 Å) 主引用文献 Determinants of small ubiquitin-like modifier 1 (SUMO1) protein specificity, E3 ligase, and SUMO-RanGAP1 binding activities of nucleoporin RanBP2. J.Biol.Chem., 287, 2012
3UJ0	Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form. 分子名称: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 著者 Ikura, M, Seo, M.D, Ishiyama, N, Stathopulos, P. 登録日 2011-11-07 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature, 483, 2012
3UC0	Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 分子名称: GLYCEROL, Heavy chain, monoclonal antibody 5H2, ... 著者 Cockburn, J.J.B, Stura, E.A, Navarro-Sanchez, M.E, Rey, F.A. 登録日 2011-10-25 公開日 2011-12-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Structural insights into the neutralization mechanism of a higher primate antibody against dengue virus. Embo J., 31, 2012
3UCW	Structure of MG2+ bound N-Terminal domain of Calmodulin 分子名称: Calmodulin, MAGNESIUM ION 著者 Senguen, F.T, Grabarek, Z. 登録日 2011-10-27 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand. Biochemistry, 51, 2012
3ULH	Crystal structure of a RNA binding domain of THO complex subunit 4 protein (THOC4) from Homo sapiens at 2.54 A resolution 分子名称: PHOSPHATE ION, THO complex subunit 4 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-11-10 公開日 2011-12-07 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Crystal structure of a RNA binding domain of THO complex subunit 4 protein (THOC4) from Homo sapiens at 2.54 A resolution To be published
3UDE	Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1B 分子名称: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[1-(2-{[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}ethyl)piperidin-4-yl]-5'-thioadenosine, ACETATE ION 著者 Shaw, G, Shi, G, Ji, X. 登録日 2011-10-28 公開日 2012-01-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.881 Å) 主引用文献 Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties. Bioorg.Med.Chem., 20, 2012

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