PDB: 20558 件ウェブページステータス検索Chemie searchBIRD

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3MF0	Crystal structure of PDE5A GAF domain (89-518) 分子名称: cGMP-specific 3',5'-cyclic phosphodiesterase 著者 Wang, H, Robinson, H, Ke, H. 登録日 2010-04-01 公開日 2010-09-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Conformation changes, N-terminal involvement, and cGMP signal relay in the phosphodiesterase-5 GAF domain. J.Biol.Chem., 285, 2010
3MMN	Crystal structure of the receiver domain of the histidine kinase CKI1 from Arabidopsis thaliana complexed with Mg2+ 分子名称: Histidine kinase homolog, MAGNESIUM ION 著者 Marek, J, Klumpler, T, Pekarova, B, Triskova, O, Horak, J, Zidek, L, Dopitova, R, Hejatko, J, Janda, L. 登録日 2010-04-20 公開日 2011-04-13 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and binding specificity of the receiver domain of sensor histidine kinase CKI1 from Arabidopsis thaliana. Plant J., 67, 2011
3M5C	Crystal structure of N-acetyl-L-ornithine transcarbamylase K302E mutant complexed with PALAO 分子名称: N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION 著者 Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. 登録日 2010-03-12 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010
3MPN	F177R1 mutant of LeuT 分子名称: CHLORIDE ION, LEUCINE, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ... 著者 Kroncke, B.M. 登録日 2010-04-27 公開日 2010-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural origins of nitroxide side chain dynamics on membrane protein alpha-helical sites. Biochemistry, 49, 2010
3MWV	Crystal structure of HCV NS5B polymerase 分子名称: Genome polyprotein 著者 Coulombe, R. 登録日 2010-05-06 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Importance of ligand bioactive conformation in the discovery of potent indole-diamide inhibitors of the hepatitis C virus NS5B. J.Am.Chem.Soc., 132, 2010
3MWW	Crystal structure of HCV NS5B polymerase 分子名称: 1-[2-(4-carboxypiperidin-1-yl)-2-oxoethyl]-3-cyclohexyl-2-furan-3-yl-1H-indole-6-carboxylic acid, Genome polyprotein, SULFATE ION 著者 Coulombe, R. 登録日 2010-05-06 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Importance of ligand bioactive conformation in the discovery of potent indole-diamide inhibitors of the hepatitis C virus NS5B. J.Am.Chem.Soc., 132, 2010
3PA0	Crystal Structure of Chiral Gamma-PNA with Complementary DNA Strand: Insight Into the Stability and Specificity of Recognition an Conformational Preorganization 分子名称: 1,2-ETHANEDIOL, DNA 5'-D(*AP*TP*CP*TP*GP*TP*GP*GP*TP*C)-3', PEPTIDE NUCLEIC ACID, ... 著者 Yeh, J.I, Shivachev, B, Du, S. 登録日 2010-10-18 公開日 2010-12-29 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of chiral gammaPNA with complementary DNA strand: insights into the stability and specificity of recognition and conformational preorganization. J.Am.Chem.Soc., 132, 2010
3OWS	Crystal Structure of Ketosteroid Isomerase D40N/C69S/C81S/C97S/M116C-CN from P. putida with Bound Equilenin 分子名称: EQUILENIN, Steroid Delta-isomerase 著者 Sigala, P.A, Fenn, T.D, Herschlag, D. 登録日 2010-09-20 公開日 2011-09-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site. Proc.Natl.Acad.Sci.USA, 109, 2013
3OX7	The crystal structure of uPA complex with peptide inhibitor MH027 at pH4.6 分子名称: MH027, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Jiang, L.G, Andreasen, P.A, Huang, M.D. 登録日 2010-09-21 公開日 2011-08-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 The binding mechanism of a peptidic cyclic serine protease inhibitor J.Mol.Biol., 412, 2011
3P4K	The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution 分子名称: MAP kinase 14, Mitogen-activated protein kinase 14 著者 Akella, R, Min, X, Wu, Q, Gardner, K.H, Goldsmith, E.J. 登録日 2010-10-06 公開日 2011-01-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 The third conformation of p38a MAP kinase observed in phosphorylated p38a and in solution Structure, 18, 2010
4H5V	HSC70 NBD with Mg 分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
3P7J	Drosophila HP1a chromo shadow domain 分子名称: GLYCEROL, Heterochromatin protein 1 著者 Kim, D, Chruszcz, M, Minor, W, Khorasanizadeh, S. 登録日 2010-10-12 公開日 2011-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The HP1a Disordered C Terminus and Chromo Shadow Domain Cooperate to Select Target Peptide Partners. Chembiochem, 12, 2011
3N1W	Human FPPS COMPLEX WITH FBS_02 分子名称: (5-chloro-1-benzothiophen-3-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-17 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N52	crystal Structure analysis of MIP2 分子名称: C-X-C motif chemokine 2 著者 Rajasekaran, D. 登録日 2010-05-24 公開日 2011-06-08 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Model of GAG/MIP-2/CXCR2 Interfaces and Its Functional Effects. Biochemistry, 51, 2012
3N5C	Crystal Structure of Arf6DELTA13 complexed with GDP 分子名称: ADP-ribosylation factor 6, CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE 著者 Aizel, K, Biou, V, Cherfils, J. 登録日 2010-05-25 公開日 2010-08-18 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6. J.Mol.Biol., 402, 2010
3NBY	Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex 分子名称: Exportin-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Guttler, T, Madl, T, Neumann, P, Deichsel, D, Corsini, L, Monecke, T, Ficner, R, Sattler, M, Gorlich, D. 登録日 2010-06-04 公開日 2010-10-27 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.42 Å) 主引用文献 NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1. Nat.Struct.Mol.Biol., 17, 2010
4H5R	HSC70 NBD with Na, Cl and glycerol 分子名称: CHLORIDE ION, GLYCEROL, Heat shock cognate 71 kDa protein, ... 著者 Stec, B. 登録日 2012-09-18 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 New crystal structures of HSC-70 ATP binding domain confirm the role of individual binding pockets and suggest a new method of inhibition. Biochimie, 108, 2015
1HD7	A Second Divalent Metal Ion in the Active Site of a New Crystal Form of Human Apurinic/Apyridinimic Endonuclease, Ape1, and its Implications for the Catalytic Mechanism 分子名称: DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE, LEAD (II) ION 著者 Beernink, P.T, Segelke, B.W, Rupp, B. 登録日 2000-11-09 公開日 2001-02-16 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Two Divalent Metal Ions in the Active Site of a New Crystal Form of Human Apurinic/Apyrimidinic Endonuclease, Ape1: Implications for the Catalytic Mechanism J.Mol.Biol., 307, 2001
4HVU	Crystal structure of the T98D c-Src-SH3 domain mutant in complex with the high affinity peptide APP12 分子名称: ACETYL GROUP, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ... 著者 Camara-Artigas, A. 登録日 2012-11-07 公開日 2013-05-01 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Atomic resolution structures of the c-Src SH3 domain in complex with two high-affinity peptides from classes I and II. Acta Crystallogr.,Sect.D, 69, 2013
3N1V	Human FPPS COMPLEX WITH FBS_01 分子名称: (5-chloro-3-methyl-1-benzothiophen-2-yl)acetic acid, FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION 著者 Rondeau, J.-M. 登録日 2010-05-17 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3N49	Human FPPS COMPLEX WITH NOV_292 分子名称: FARNESYL PYROPHOSPHATE SYNTHASE, PHOSPHATE ION, naphtho[2,1-b]thiophen-1-ylacetic acid 著者 Rondeau, J.-M. 登録日 2010-05-21 公開日 2010-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. Nat.Chem.Biol., 6, 2010
3O9X	Structure of the E. coli antitoxin MqsA (YgiT/b3021) in complex with its gene promoter 分子名称: DNA (26-MER), GLYCEROL, Uncharacterized HTH-type transcriptional regulator ygiT, ... 著者 Brown, B.L, Peti, W, Page, R. 登録日 2010-08-04 公開日 2010-11-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.0999 Å) 主引用文献 Structure of the Escherichia coli Antitoxin MqsA (YgiT/b3021) Bound to Its Gene Promoter Reveals Extensive Domain Rearrangements and the Specificity of Transcriptional Regulation. J.Biol.Chem., 286, 2011
3OFW	Crystal structure of recombinant Kunitz Type serine protease Inhibitor-1 from the Carribean sea anemone stichodactyla helianthus 分子名称: CHLORIDE ION, Kunitz-type proteinase inhibitor SHPI-1 著者 Garcia-Fernandez, R, Redecke, L, Pons, T, Perbandt, M, Talavera, A, Gil, D, Gonzalez, Y, de los Angeles Chavez, M, Betzel, C. 登録日 2010-08-16 公開日 2011-08-17 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus. Acta Crystallogr.,Sect.F, 68, 2012
3OGN	Crystal Structure of an Odorant-binding Protein from the Southern House Mosquito Complexed with an Oviposition Pheromone 分子名称: (1S)-1-[(2R)-6-oxotetrahydro-2H-pyran-2-yl]undecyl acetate, MAGNESIUM ION, Odorant-binding protein 著者 Mao, Y, Clardy, J. 登録日 2010-08-17 公開日 2010-11-03 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal and solution structures of an odorant-binding protein from the southern house mosquito complexed with an oviposition pheromone. Proc.Natl.Acad.Sci.USA, 107, 2010
3M5D	Crystal structure of N-acetyl-L-ornithine transcarbamylase K302R mutant complexed with PALAO 分子名称: N-acetylornithine carbamoyltransferase, N~2~-acetyl-N~5~-(phosphonoacetyl)-L-ornithine, SULFATE ION 著者 Li, Y, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. 登録日 2010-03-12 公開日 2010-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Reversible post-translational carboxylation modulates the enzymatic activity of N-acetyl-L-ornithine transcarbamylase. Biochemistry, 49, 2010

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