PDB: 97310 件ウェブページステータス検索Chemie searchBIRD

---

7QQU	SpCas9 bound to FANCF off-target2 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQT	SpCas9 bound to FANCF off-target1 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR8	SpCas9 bound to PTPRC off-target1 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQX	SpCas9 bound to FANCF off-target5 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR0	SpCas9 bound to TRAC off-target1 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
8FVY	40S subunit of the Giardia lamblia 80S ribosome 分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ... 著者 Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S. 登録日 2023-01-20 公開日 2024-01-24 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (2.94 Å) 主引用文献 The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function. Structure, 32, 2024
7QQZ	SpCas9 bound to FANCF off-target7 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QQW	SpCas9 bound to FANCF off-target4 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR1	SpCas9 bound to TRAC off-target2 DNA substrate 分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ... 著者 Pacesa, M, Jinek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QR7	SpCas9 bound to AAVS1 off-target2 DNA substrate 分子名称: AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA, ... 著者 Pacesa, M, JInek, M. 登録日 2022-01-10 公開日 2022-10-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for Cas9 off-target activity. Cell, 185, 2022
7QDA	Crystal structure of CalpL 分子名称: CalpL, SULFATE ION, TETRAETHYLENE GLYCOL, ... 著者 Schneberger, N, Hagelueken, G. 登録日 2021-11-26 公開日 2022-11-16 最終更新日 2023-02-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Antiviral signalling by a cyclic nucleotide activated CRISPR protease. Nature, 614, 2023
3UPJ	HUMAN IMMUNODEFICIENCY VIRUS TYPE 2 PROTEASE MUTANT WITH LYS 57 REPLACED BY LEU (K57L) COMPLEX WITH U096333 [4-HYDROXY-3-[1-(PHENYL)PROPYL]-7-METHOXYCOUMARIN] 分子名称: 4-HYDROXY-7-METHOXY-3-(1-PHENYL-PROPYL)-CHROMEN-2-ONE, HIV-2 PROTEASE 著者 Watenpaugh, K.D, Mulichak, A.M, Janakiraman, M.N. 登録日 1996-03-04 公開日 1996-10-14 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based design of novel HIV protease inhibitors: carboxamide-containing 4-hydroxycoumarins and 4-hydroxy-2-pyrones as potent nonpeptidic inhibitors. J.Med.Chem., 38, 1995
2WT8	Structure of the N-terminal BRCT domain of human microcephalin (Mcph1) 分子名称: ACETATE ION, CHLORIDE ION, MICROCEPHALIN 著者 Richards, M.W, Roe, S.M, Bayliss, R. 登録日 2009-09-14 公開日 2009-12-01 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A Pocket on the Surface of the N-Terminal Brct Domain of Mcph1 is Required to Prevent Abnormal Chromosome Condensation. J.Mol.Biol., 395, 2010
7QSQ	Permutated N-terminal lobe of the ribose binding protein from Thermotoga maritima 分子名称: 1,2-ETHANEDIOL, Ribose ABC transporter, periplasmic ribose-binding protein, ... 著者 Shanmugaratnam, S, Michel, F, Hocker, B. 登録日 2022-01-14 公開日 2023-01-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structures of permuted halves of a modern ribose-binding protein. Acta Crystallogr D Struct Biol, 79, 2023
7QSP	Permutated C-terminal lobe of the ribose binding protein from Thermotoga maritima 分子名称: 1,2-ETHANEDIOL, Ribose ABC transporter, periplasmic ribose-binding protein 著者 Shanmugaratnam, S, Michel, F, Hocker, B. 登録日 2022-01-14 公開日 2023-01-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Structures of permuted halves of a modern ribose-binding protein. Acta Crystallogr D Struct Biol, 79, 2023
6Z1M	Structure of an Ancestral glycosidase (family 1) bound to heme 分子名称: 1,2-ETHANEDIOL, Ancestral reconstructed glycosidase, GLYCEROL, ... 著者 Gavira, J.A, Risso, V.A, Sanchez-Ruiz, J.M, Gamiz-Arco, G, Gutierrez-Rus, L, Ibarra-Molero, B, Oshino, Y, Petrovic, D, Romero-Rivera, A, Seelig, B, Kamerlin, S.C.L, Gaucher, E.A. 登録日 2020-05-14 公開日 2020-07-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase. Nat Commun, 12, 2021
6ZD9	Crystal structure of YTHDC1 apo purified using GST tag 分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, YTHDC1 著者 Bedi, R.K, Caflisch, A. 登録日 2020-06-14 公開日 2020-07-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
6T4D	Crystal structure of Plasmodium falciparum Morn1 分子名称: Morn1, ZINC ION 著者 Grishkovskaya, I, Kostan, J, Sajko, S, Morriswood, B, Djinovic-Carugo, K. 登録日 2019-10-13 公開日 2020-11-18 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats. Plos One, 15, 2020
6ZD7	Crystal structure of YTHDC1 T379V mutant complex with m6A 分子名称: N-methyladenosine, SULFATE ION, YTH domain containing 1 著者 Bedi, R.K, Li, Y, Caflisch, A. 登録日 2020-06-13 公開日 2021-01-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Atomistic and Thermodynamic Analysis of N6-Methyladenosine (m 6 A) Recognition by the Reader Domain of YTHDC1. J Chem Theory Comput, 17, 2021
7R9E	Methanococcus maripaludis chaperonin, open conformation 1 分子名称: Chaperonin 著者 Zhao, Y, Schmid, M, Frydman, J, Chiu, W. 登録日 2021-06-29 公開日 2021-08-11 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 CryoEM reveals the stochastic nature of individual ATP binding events in a group II chaperonin. Nat Commun, 12, 2021
6SGC	Rabbit 80S ribosome stalled on a poly(A) tail 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Chandrasekaran, V, Juszkiewicz, S, Choi, J, Puglisi, J.D, Brown, A, Shao, S, Ramakrishnan, V, Hegde, R.S. 登録日 2019-08-03 公開日 2019-12-04 最終更新日 2022-03-30 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanism of ribosome stalling during translation of a poly(A) tail. Nat.Struct.Mol.Biol., 26, 2019
6Z3W	Human ER membrane protein complex 分子名称: ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... 著者 Hegde, R.S, O'Donnell, J.P. 登録日 2020-05-22 公開日 2020-07-15 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 The architecture of EMC reveals a path for membrane protein insertion. Elife, 9, 2020
6ZYN	Structure of VIM-2 with 2-Mercaptomethyl-thiazolidine L-anti-1b 分子名称: (2~{S},4~{R})-2-ethoxycarbonyl-5,5-dimethyl-2-(sulfanylmethyl)-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase VIM-2, FORMIC ACID, ... 著者 Hinchliffe, P, Spencer, J. 登録日 2020-08-02 公開日 2021-01-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4000138 Å) 主引用文献 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-beta-lactamases. Chem Sci, 12, 2021
7R65	Crystal structure of a bacterial cyclic UMP synthase from Burkholderia cepacia LK29 分子名称: Adenylate/guanylate cyclase 著者 Morehouse, B.R, Kranzusch, P.J. 登録日 2021-06-22 公開日 2021-10-13 最終更新日 2021-11-24 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Cyclic CMP and cyclic UMP mediate bacterial immunity against phages. Cell, 184, 2021
3UNC	Crystal Structure of Bovine Milk Xanthine Dehydrogenase to 1.65A Resolution 分子名称: 2-HYDROXYBENZOIC ACID, CALCIUM ION, CARBONATE ION, ... 著者 Eger, B.T, Okamoto, K, Nishino, T, Pai, E.F. 登録日 2011-11-15 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Protein conformational gating of enzymatic activity in xanthine oxidoreductase. J.Am.Chem.Soc., 134, 2012

<618619620621622623624625626627628629630631632633>