PDB: 72236 件ウェブページステータス検索Chemie searchBIRD

---

3P9K	Crystal structure of perennial ryegrass LpOMT1 complexed with S-adenosyl-L-homocysteine and coniferaldehyde 分子名称: (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal, Caffeic acid O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Louie, G.V, Noel, J.P, Bowman, M.E. 登録日 2010-10-17 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-Function Analyses of a Caffeic Acid O-Methyltransferase from Perennial Ryegrass Reveal the Molecular Basis for Substrate Preference. Plant Cell, 22, 2010
1K33	Crystal structure analysis of the gp41 core mutant 分子名称: Transmembrane glycoprotein GP41 著者 Shu, W, Lu, M. 登録日 2001-10-01 公開日 2001-10-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Interhelical interactions in the gp41 core: implications for activation of HIV-1 membrane fusion. Biochemistry, 41, 2002
6RZU	Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the GTPgammaS bound state 分子名称: Putative mitochondrial dynamin protein 著者 Faelber, K, Dietrich, L, Noel, J.K, Sanchez, R, Kudryashev, M, Kuelbrandt, W, Daumke, O. 登録日 2019-06-13 公開日 2019-07-24 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (14.7 Å) 主引用文献 Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature, 571, 2019
1JD3	Chorismate lyase G90A mutant with bound product 分子名称: P-HYDROXYBENZOIC ACID, chorismate lyase 著者 Mayhew, M, Smith, N, Holden, M.J, Gallagher, D.T. 登録日 2001-06-12 公開日 2001-06-20 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural analysis of ligand binding and catalysis in chorismate lyase. Arch.Biochem.Biophys., 445, 2006
3OWB	Crystal Structure of HSP90 with VER-49009 分子名称: 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-(4-METHOXYPHENYL)-1H-PYRAZOLE-3-CARBOXAMIDE, Heat shock protein HSP 90-alpha 著者 Park, C.H. 登録日 2010-09-17 公開日 2011-09-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 N-aryl-benzimidazolones as novel small molecule HSP90 inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
6G2L	Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PMTMU 分子名称: 5'(3')-deoxyribonucleotidase, mitochondrial, BETA-MERCAPTOETHANOL, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2018-03-23 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structure-based optimization of bisphosphonate nucleoside inhibitors of human 5'(3')-deoxyribonucleotidases Eur.J.Org.Chem., 2018
1JIK	Crystal structure of S. aureus TyrRS in complex with SB-243545 分子名称: [2-AMINO-3-(4-HYDROXY-PHENYL)-PROPIONYLAMINO]-(1,3,4,5-TETRAHYDROXY-4-HYDROXYMETHYL-PIPERIDIN-2-YL)- ACETIC ACID BUTYL ESTER, tyrosyl-tRNA synthetase 著者 Qiu, X, Janson, C.A, Smith, W.W, Jarvest, R.L. 登録日 2001-07-02 公開日 2001-10-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of Staphylococcus aureus tyrosyl-tRNA synthetase in complex with a class of potent and specific inhibitors. Protein Sci., 10, 2001
6RZT	Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes 分子名称: Putative mitochondrial dynamin protein 著者 Faelber, K, Dietrich, L, Noel, J.K, Sanchez, R, Kudryashev, M, Kuehlbrandt, W, Daumke, O. 登録日 2019-06-13 公開日 2019-07-24 最終更新日 2020-11-18 実験手法 ELECTRON MICROSCOPY (14.7 Å) 主引用文献 Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1. Nature, 571, 2019
6S05	Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Kargas, V, Warren, A.J. 登録日 2019-06-13 公開日 2019-06-26 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of completion of peptidyltransferase centre assembly in eukaryotes. Elife, 8, 2019
6S35	LSD1/CoREST1 complex with macrocyclic peptide inhibitor 分子名称: ALA-ARG-(D)LYS-MET-GLN-GLU-ALA-ARG-LYS-SER-THR, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... 著者 Talibov, V.O, Dobritzsch, D. 登録日 2019-06-24 公開日 2020-02-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1. Acs Omega, 5, 2020
6FVQ	The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A 分子名称: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside 著者 Hu, H, Delarue, M. 登録日 2018-03-05 公開日 2018-05-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6G22	Crystal structure of human mitochondrial 5'(3')-deoxyribonucleotidase in complex with the inhibitor PB-PEU 分子名称: 1-{2-deoxy-3,5-O-[phenyl(phosphono)methylidene]-beta-D-threo-pentofuranosyl}-5-[(E)-2-phosphonoethenyl]pyrimidine-2,4(1H,3H)-dione, 5'(3')-deoxyribonucleotidase, mitochondrial, ... 著者 Pachl, P, Rezacova, P, Brynda, J. 登録日 2018-03-22 公開日 2018-07-11 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-based optimization of bisphosphonate nucleoside inhibitors of human 5'(3')-deoxyribonucleotidases Eur.J.Org.Chem., 2018
6TQY	Crystal structure of ribonucleotide reductase NrdF L61G variant from Bacillus anthracis anaerobically soaked with Fe(II) and Mn(II) ions 分子名称: MANGANESE (II) ION, Ribonucleoside-diphosphate reductase subunit beta, SULFATE ION 著者 Grave, K, Hogbom, M. 登録日 2019-12-17 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 The Bacillus anthracis class Ib ribonucleotide reductase subunit NrdF intrinsically selects manganese over iron. J.Biol.Inorg.Chem., 25, 2020
6TM0	N-Domain P40/P90 Mycoplasma pneumoniae complexed with 6'SL 分子名称: Mgp-operon protein 3, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Vizarraga, D, Aparicio, D, Illanes, R, Fita, I, Perez-Luque, R, Martin, J. 登録日 2019-12-03 公開日 2020-11-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Immunodominant proteins P1 and P40/P90 from human pathogen Mycoplasma pneumoniae. Nat Commun, 11, 2020
3N58	Crystal structure of S-ADENOSYL-L-HOMOCYSTEINE hydrolase from brucella melitensis in ternary complex with NAD and adenosine, orthorhombic form 分子名称: ADENOSINE, Adenosylhomocysteinase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-05-24 公開日 2010-06-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystal structure of S-adenosyl-L-homocysteine hydrolase from brucella melitensis in ternary complex with NAD and adenosine, orthorhombic form To be Published
1KLF	FIMH ADHESIN-FIMC CHAPERONE COMPLEX WITH D-MANNOSE 分子名称: CHAPERONE PROTEIN FIMC, FIMH PROTEIN, alpha-D-mannopyranose 著者 Hung, C.S, Bouckaert, J. 登録日 2001-12-11 公開日 2002-06-05 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol., 44, 2002
6TNR	PI3K delta in complex with N[5(7{2[4(2hydroxypropan2yl)piperidin1 yl]ethoxy}1,3dihydro2benzofuran5yl)2 methoxypyridin3yl]methanesulfonamide 分子名称: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, ~{N}-[2-methoxy-5-[7-[2-[4-(2-oxidanylpropan-2-yl)piperidin-1-yl]ethoxy]-1,3-dihydro-2-benzofuran-5-yl]pyridin-3-yl]methanesulfonamide 著者 Convery, M.A, Rowland, P, Henley, Z.A, Barton, N, Down, K. 登録日 2019-12-10 公開日 2020-01-01 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Optimization of Orally Bioavailable PI3K delta Inhibitors and Identification of Vps34 as a Key Selectivity Target. J.Med.Chem., 63, 2020
6F83	Crystal Structure of Human Galectin-1 in Complex With Thienyl-1,2, 3-triazolyl Thiodigalactoside Inhibitor 分子名称: 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside, Galectin-1 著者 Collins, P.M, Blanchard, H. 登録日 2017-12-12 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands To be published
6T5K	ECV-1 from Echinicola vietnamensis. Environmental metallo-beta-lactamases exhibit high enzymatic activity under zinc deprivation 分子名称: 1,2-ETHANEDIOL, ZINC ION, Zn-dependent hydrolase, ... 著者 Frohlich, C. 登録日 2019-10-16 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.33 Å) 主引用文献 Structural and biochemical characterization of the environmental MBLs MYO-1, ECV-1 and SHD-1. J.Antimicrob.Chemother., 75, 2020
1KIU	FimH adhesin Q133N mutant-FimC chaperone complex with methyl-alpha-D-mannose 分子名称: CHAPERONE PROTEIN FimC, FimH PROTEIN, methyl alpha-D-mannopyranoside 著者 Hung, C.S, Bouckaert, J. 登録日 2001-12-03 公開日 2002-06-05 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of tropism of Escherichia coli to the bladder during urinary tract infection. Mol.Microbiol., 44, 2002
3MZH	Crystal structure of cAMP receptor protein from mycobacterium tuberculosis in complex with cAMP and its DNA binding element 分子名称: 5'-D(P*AP*AP*AP*TP*GP*TP*GP*AP*TP*CP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*G)-3', 5'-D(P*CP*AP*CP*GP*TP*GP*AP*CP*CP*TP*AP*GP*AP*TP*CP*AP*CP*AP*TP*C)-3', ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ... 著者 Akhter, Y, Wilmanns, M. 登録日 2010-05-12 公開日 2011-06-08 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Camp Receptor Protein from Mycobacterium Tuberculosis in Complex with DNA and cAMP To be Published
3PAW	Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site 分子名称: Ribonucleoside-diphosphate reductase large chain 1 著者 Fairman, J.W, Wijerathna, S.R, Dealwis, C.G. 登録日 2010-10-19 公開日 2011-02-23 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (6.61 Å) 主引用文献 Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization. Nat.Struct.Mol.Biol., 18, 2011
6T69	Crystal structure of Toxoplasma gondii Morn1(V shape) 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Membrane occupation and recognition nexus protein MORN1, ... 著者 Grishkovskaya, I, Kostan, J, Sajko, S, Morriswood, B, Djinovic-Carugo, K. 登録日 2019-10-18 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats. Plos One, 15, 2020
6T6B	Crystal structure of PPARgamma in complex with compound 16 (MF27) 分子名称: (2~{R})-2-[[6-[(2,4-dichlorophenyl)sulfonylamino]-1,3-benzothiazol-2-yl]sulfanyl]octanoic acid, Peroxisome proliferator-activated receptor gamma 著者 Chaikuad, A, Ni, X, Hanke, T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2019-10-18 公開日 2019-12-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A Selective Modulator of Peroxisome Proliferator-Activated Receptor gamma with an Unprecedented Binding Mode. J.Med.Chem., 63, 2020
3OVX	Cathepsin S in complex with a covalent inhibitor with an aldehyde warhead 分子名称: 2-chloro-N-[(1S)-1-formylpropyl]-3-(trifluoromethyl)benzamide, Cathepsin S, DIMETHYL SULFOXIDE 著者 Fradera, X, van Zeeland, M, Uitdehaag, J.C.M. 登録日 2010-09-17 公開日 2010-12-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors. Bioorg.Med.Chem.Lett., 20, 2010

<613614615616617618619620621622623624625626627628>