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8DNQ
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BRD2-BD1 in complex with cyclic peptide 2.2B
分子名称: Bromodomain-containing protein 2, Cyclic peptide 2.2B, GLYCEROL
著者Patel, K, Franck, C, Mackay, J.P.
登録日2022-07-11
公開日2023-07-19
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins.
Structure, 31, 2023
5JLI
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BU of 5jli by Molmil
Nitric oxide complex of the L16A mutant of cytochrome c prime from Alcaligenes xylosoxidans
分子名称: ASCORBIC ACID, Cytochrome c', HEME C, ...
著者Kekilli, D, Strange, R.W, Hough, M.A.
登録日2016-04-27
公開日2017-03-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design.
Chem Sci, 8, 2017
8BC6
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Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex an aspartimide degron peptide
分子名称: Cereblon isoform 4, GLN-MET-GLN-SNN, PHOSPHATE ION, ...
著者Heim, C, Hartmann, M.D.
登録日2022-10-15
公開日2023-01-11
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon.
Biochem.Biophys.Res.Commun., 637, 2022
5JRA
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BU of 5jra by Molmil
Nitric oxide complex of the L16V mutant of cytochrome c prime from Alcaligenes xylosoxidans
分子名称: ASCORBIC ACID, Cytochrome c', HEME C, ...
著者Kekilli, D, Strange, R.W, Hough, M.A.
登録日2016-05-06
公開日2017-03-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design.
Chem Sci, 8, 2017
8BC7
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BU of 8bc7 by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex an aminoglutarimide degron peptide
分子名称: Cereblon isoform 4, PHE-PHE-GLU-GLN-MET-GLN-QCI, S-Thalidomide, ...
著者Heim, C, Albrecht, R, Spring, A.K, Hartmann, M.D.
登録日2022-10-15
公開日2023-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.719 Å)
主引用文献Identification and structural basis of C-terminal cyclic imides as natural degrons for cereblon.
Biochem.Biophys.Res.Commun., 637, 2022
1GU2
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Crystal structure of oxidized cytochrome c'' from Methylophilus methylotrophus
分子名称: CYTOCHROME C'', HEME C
著者Enguita, F.J, Pohl, E, Rodrigues, A, Santos, H, Carrondo, M.A.
登録日2002-01-22
公開日2003-01-16
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.19 Å)
主引用文献Structural Evidence for a Proton Transfer Pathway Coupled with Haem Reduction of Cytochrome C" from Methylophilus Methylotrophus.
J.Biol.Inorg.Chem., 11, 2006
7ZS8
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BU of 7zs8 by Molmil
Mixed-valence, active form, of cytochrome c peroxidase from obligate human pathogenic bacterium Neisseria gonorrhoeae at 1.4 Angstrom resolution
分子名称: CALCIUM ION, Cytochrome-c peroxidase, HEME C, ...
著者Carvalho, A.L, Romao, M.J, Pauleta, S, Nobrega, C.
登録日2022-05-06
公開日2023-04-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural Characterization of Neisseria gonorrhoeae Bacterial Peroxidase-Insights into the Catalytic Cycle of Bacterial Peroxidases.
Int J Mol Sci, 24, 2023
8A8X
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BU of 8a8x by Molmil
TRIM7 PRYSPRY in complex with a MNV1-NS3 peptide HDDFGLQ
分子名称: E3 ubiquitin-protein ligase TRIM7, MNV1-NS3 C term peptide
著者Luptak, J.
登録日2022-06-24
公開日2022-07-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
Viruses, 14, 2022
5GMJ
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BU of 5gmj by Molmil
Crystal Structure of GRASP55 GRASP domain in complex with JAM-B C-terminus
分子名称: Golgi reassembly-stacking protein 2, Junctional adhesion molecule B
著者Shi, N, Shi, X, Morelli, X, Betzi, S, Huang, X.
登録日2016-07-14
公開日2017-05-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.986 Å)
主引用文献Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis
PLoS Genet., 13, 2017
5H65
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BU of 5h65 by Molmil
Crystal structure of human POT1 and TPP1
分子名称: Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION
著者Chen, C, Wu, J, Lei, M.
登録日2016-11-10
公開日2017-05-31
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancer.
Nat Commun, 8, 2017
1S6V
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BU of 1s6v by Molmil
Structure of a cytochrome c peroxidase-cytochrome c site specific cross-link
分子名称: Cytochrome c peroxidase, mitochondrial, Cytochrome c, ...
著者Guo, M, Bhaskar, B, Li, H, Barrows, T.P, Poulos, T.L.
登録日2004-01-27
公開日2004-04-27
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Crystal structure and characterization of a cytochrome c peroxidase-cytochrome c site-specific cross-link
Proc.Natl.Acad.Sci.USA, 101, 2004
7RXP
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BU of 7rxp by Molmil
Fab1512 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab1512 heavy chain, Fab1512 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.761 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7RXI
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Fab234 in complex with the C-terminal alpha-TSR domain of P. falciparum
分子名称: Circumsporozoite protein, Fab234 heavy chain, Fab234 light chain
著者Pholcharee, T, Oyen, D, Wilson, I.A.
登録日2021-08-23
公開日2022-03-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献A novel CSP C-terminal epitope targeted by an antibody with protective activity against Plasmodium falciparum.
Plos Pathog., 18, 2022
7SJ1
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BU of 7sj1 by Molmil
Structure of shaker-W434F
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
著者Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
登録日2021-10-15
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
7SIP
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Structure of shaker-IR
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, POTASSIUM ION, Potassium voltage-gated channel protein Shaker
著者Tan, X, Bae, C, Stix, R, Fernandez, A.I, Huffer, K, Chang, T, Jiang, J, Faraldo-Gomez, J.D, Swartz, K.J.
登録日2021-10-14
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the Shaker Kv channel and mechanism of slow C-type inactivation.
Sci Adv, 8, 2022
5EPY
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BU of 5epy by Molmil
Crystal structure of HCV NS3/4A protease A156T variant in complex with 5172-mcP1P3 (MK-5172 P1-P3 macrocyclic analogue)
分子名称: 2-Methyl-2-propanyl {(2R,6S,12Z,13aS,14aR,16aS)-14a-[(cyclopropylsulfonyl)carbamoyl]-2-[(3-ethyl-7-methoxy-2-quinoxalinyl)oxy]-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclop ropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl}carbamate, NS3 protease, SULFATE ION, ...
著者Soumana, D.I, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Aydin, C, Schiffer, C.A.
登録日2015-11-12
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172.
Acs Chem.Biol., 11, 2016
6IQQ
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BU of 6iqq by Molmil
Crystal structure of Prc with S452I and L252Y mutations in complex with NlpI
分子名称: CALCIUM ION, Lipoprotein NlpI, Tail-specific protease
著者Chueh, C.K, Chang, C.I.
登録日2018-11-08
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
5EQQ
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BU of 5eqq by Molmil
Crystal structure of HCV NS3/4A WT protease in complex with 5172-Linear (MK-5172 linear analogue)
分子名称: NS3 protease, SULFATE ION, ZINC ION, ...
著者Soumana, D, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Aydin, C, Schiffer, C.A.
登録日2015-11-13
公開日2016-01-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172.
Acs Chem.Biol., 11, 2016
5EPN
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BU of 5epn by Molmil
Crystal structure of HCV NS3/4A protease in complex with 5172-mcP1P3 (MK-5172 P1-P3 macrocyclic analogue)
分子名称: 2-Methyl-2-propanyl {(2R,6S,12Z,13aS,14aR,16aS)-14a-[(cyclopropylsulfonyl)carbamoyl]-2-[(3-ethyl-7-methoxy-2-quinoxalinyl)oxy]-5,16-dioxo-1,2,3,5,6,7,8,9,10,11,13a,14,14a,15,16,16a-hexadecahydrocyclop ropa[e]pyrrolo[1,2-a][1,4]diazacyclopentadecin-6-yl}carbamate, NS3 protease, SULFATE ION, ...
著者Soumana, D.I, Yilmaz, N.K, Ali, A, Prachanronarong, K.L, Aydin, C, Schiffer, C.A.
登録日2015-11-11
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and Thermodynamic Effects of Macrocyclization in HCV NS3/4A Inhibitor MK-5172.
Acs Chem.Biol., 11, 2016
5MCS
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BU of 5mcs by Molmil
Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens
分子名称: HEME C, Lipoprotein cytochrome c, 1 heme-binding site
著者Dantas, J.M, Silva, M.A, Morgado, L, Pantoja-Uceda, D, Turner, D.L, Bruix, M, Salgueiro, C.A.
登録日2016-11-10
公開日2017-04-12
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure and dynamics of the outer membrane cytochrome OmcF from Geobacter sulfurreducens.
Biochim. Biophys. Acta, 1858, 2017
6LBF
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BU of 6lbf by Molmil
Crystal structure of FEM1B
分子名称: Protein fem-1 homolog B, SULFATE ION
著者Chen, X, Liao, S, Xu, C.
登録日2019-11-14
公開日2020-10-21
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.252 Å)
主引用文献Molecular basis for arginine C-terminal degron recognition by Cul2 FEM1 E3 ligase.
Nat.Chem.Biol., 17, 2021
6EFK
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BU of 6efk by Molmil
Crystal structure of the human CHIP TPR domain in complex with a 5mer acetylated HSP70 peptide
分子名称: ACE-ILE-GLU-GLU-VAL-ASP, E3 ubiquitin-protein ligase CHIP, SODIUM ION
著者Basu, K, Ravalin, M, Bohn, M.-F, Craik, C.S, Gestwicki, J.E.
登録日2018-08-16
公開日2019-07-31
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases.
Nat.Chem.Biol., 15, 2019
6A3K
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Crystal structure of cytochrome c' from Shewanella benthica DB6705
分子名称: Cytochrome c, HEME C, PENTAETHYLENE GLYCOL
著者Suka, A, Oki, H, Kato, Y, Kawahara, K, Ohkubo, T, Maruno, T, Kobayashi, Y, Fujii, S, Wakai, S, Sambongi, Y.
登録日2018-06-15
公開日2019-06-12
最終更新日2019-10-02
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Stability of cytochromes c' from psychrophilic and piezophilic Shewanella species: implications for complex multiple adaptation to low temperature and high hydrostatic pressure.
Extremophiles, 23, 2019
6IQS
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Crystal structure of Prc with L245A and L340G mutations in complex with NlpI
分子名称: Lipoprotein NlpI, Tail-specific protease
著者Chuech, C.K, Chang, C.I.
登録日2018-11-08
公開日2019-07-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Structural Basis for the Differential Regulatory Roles of the PDZ Domain in C-Terminal Processing Proteases.
Mbio, 10, 2019
6UL7
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Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole
分子名称: 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Ketohexokinase, NITRATE ION, ...
著者Gasper, W.C, Gardner, S, Allen, K.N, Tolan, D.R.
登録日2019-10-07
公開日2021-04-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of human ketohexokinase-C in complex with fructose, NO3, and osthole
To be Published

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件を2024-08-14に公開中

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