PDB: 2682 件ウェブページステータス検索Chemie searchBIRD

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6T9E	Crystal structure of a bispecific DutaFab in complex with human PDGF 分子名称: DutaFab mat VH chain, DutaFab mat VL chain, Platelet-derived growth factor subunit B 著者 Kimbung, R, Logan, D.T, Beckmann, R, Jensen, K, Speck, J, Fenn, S, Kettenberger, H. 登録日 2019-10-28 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.989 Å) 主引用文献 DutaFabs are engineered therapeutic Fab fragments that can bind two targets simultaneously. Nat Commun, 12, 2021
7AQC	Structure of the bacterial RQC complex (Decoding State) 分子名称: 23S ribosomal RNA, 50S ribosomal protein L11, 50S ribosomal protein L13, ... 著者 Filbeck, S, Pfeffer, S. 登録日 2020-10-21 公開日 2020-11-25 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.99 Å) 主引用文献 Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC. Mol.Cell, 81, 2021
8EV3	Ytm1 associated 60S nascent ribosome (-Fkbp39) State 1B 分子名称: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... 著者 Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. 登録日 2022-10-19 公開日 2022-11-30 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
8RGQ	Open Complex I from murine liver 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2023-12-14 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
6QUL	Structure of a bacterial 50S ribosomal subunit in complex with the novel quinoxolidinone antibiotic cadazolid 分子名称: 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Scaiola, A, Leibundgut, M, Boehringer, D, Ritz, D. 登録日 2019-02-27 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis of translation inhibition by cadazolid, a novel quinoxolidinone antibiotic. Sci Rep, 9, 2019
8RGP	Closed Complex I from murine brain 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2023-12-14 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
5DM7	Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with hygromycin A 分子名称: 23S ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L11, ... 著者 Kaminishi, T, Schedlbauer, A, Ochoa-Lizarralde, B, Connell, S.R, Fucini, P. 登録日 2015-09-08 公開日 2015-11-11 最終更新日 2015-11-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A. Nucleic Acids Res., 43, 2015
6KHI	Supercomplex for cylic electron transport in cyanobacteria 分子名称: 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... 著者 Pan, X, Cao, D, Xie, F, Zhang, X, Li, M. 登録日 2019-07-15 公開日 2020-02-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for electron transport mechanism of complex I-like photosynthetic NAD(P)H dehydrogenase. Nat Commun, 11, 2020
4U3M	Crystal structure of Anisomycin bound to the yeast 80S ribosome 分子名称: 18S rRNA, 25s rRNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-22 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
4U52	Crystal structure of Nagilactone C bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
7OSA	Pre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... 著者 Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2021-06-08 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Accuracy mechanism of eukaryotic ribosome translocation. Nature, 600, 2021
7OSM	Intermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands 分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... 著者 Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2021-06-09 公開日 2021-12-08 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Accuracy mechanism of eukaryotic ribosome translocation. Nature, 600, 2021
4FPB	Crystal Structure of Recombinant Human Hexokinase Type I with 1,5-Anhydroglucitol 6-Phosphate 分子名称: 1,5-anhydro-6-O-phosphono-D-glucitol, CITRIC ACID, Hexokinase-1, ... 著者 Shen, L, Honzatko, R.B. 登録日 2012-06-21 公開日 2013-07-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Inhibitor Sites of Unequal Affinity Linked by Binding Synergism in Mutant Forms of Recombinant Human Hexokinase Type-I to be published
4U4Q	Crystal structure of Homoharringtonine bound to the yeast 80S ribosome 分子名称: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
7OLD	Thermophilic eukaryotic 80S ribosome at pe/E (TI)-POST state 分子名称: 18S rRNA, 26S rRNA, 40S ribosomal protein S0, ... 著者 Kisonaite, M, Wild, K, Sinning, I. 登録日 2021-05-19 公開日 2022-01-26 最終更新日 2022-02-09 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation. Nat Commun, 13, 2022
4WOI	4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S. 登録日 2014-10-15 公開日 2015-08-05 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions. Nat Commun, 6, 2015
4U1V	Crystal structure of the E. coli ribosome bound to linopristin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. 登録日 2014-07-16 公開日 2014-07-30 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
7P7S	PoxtA-EQ2 antibiotic resistance ABCF bound to E. faecalis 70S ribosome, state II 分子名称: 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... 著者 Crowe-McAuliffe, C, Wilson, D.N. 登録日 2021-07-20 公開日 2022-02-23 最終更新日 2022-04-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics. Nat Commun, 13, 2022
4U4U	Crystal structure of Lycorine bound to the yeast 80S ribosome 分子名称: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ... 著者 Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M. 登録日 2014-07-24 公開日 2014-10-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for the inhibition of the eukaryotic ribosome. Nature, 513, 2014
6ERI	Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10 alpha, ... 著者 Perez Borema, A, Aibara, S, Paul, B, Tobiasson, V, Kimanius, D, Forsberg, B.O, Wallden, K, Lindahl, E, Amunts, A. 登録日 2017-10-18 公開日 2018-04-18 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor. Nat Plants, 4, 2018
7P69	Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... 著者 Kravchuk, V, Kampjut, D, Sazanov, L. 登録日 2021-07-15 公開日 2022-09-21 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
7P7L	Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state 分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... 著者 Kravchuk, V, Kampjut, D, Sazanov, L. 登録日 2021-07-19 公開日 2022-09-21 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
8EUY	Ytm1 associated nascent 60S ribosome (-fkbp39) State 1A 分子名称: 60S ribosomal protein L13, 60S ribosomal protein L14, 60S ribosomal protein L15-A, ... 著者 Zhou, X, Bilokapic, S, Deshmukh, A.A, Halic, M. 登録日 2022-10-19 公開日 2022-11-30 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Chromatin localization of nucleophosmin organizes ribosome biogenesis. Mol.Cell, 82, 2022
5IQR	Structure of RelA bound to the 70S ribosome 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Brown, A, Fernandez, I.S, Gordiyenko, Y, Ramakrishnan, V. 登録日 2016-03-11 公開日 2016-05-04 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Ribosome-dependent activation of stringent control. Nature, 534, 2016
1PDG	CRYSTAL STRUCTURE OF HUMAN PLATELET-DERIVED GROWTH FACTOR BB 分子名称: PLATELET-DERIVED GROWTH FACTOR BB 著者 Oefner, C, Darcy, A.D, Winkler, F.K, Eggimann, B, Hosnag, M. 登録日 1992-07-14 公開日 1994-01-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of human platelet-derived growth factor BB. EMBO J., 11, 1992

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