PDB: 19260 件ウェブページステータス検索Chemie searchBIRD

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3UQ8	Structure of adenylation domain of Haemophilus influenzae DNA ligases bound to NAD+ in adenylated state. 分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Lahiri, S.D. 登録日 2011-11-19 公開日 2012-01-25 最終更新日 2014-11-12 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure Guided Understanding of NAD(+) Recognition in Bacterial DNA Ligases. Acs Chem.Biol., 7, 2012
3UQW	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, SULFATE ION, ethyl 1-{(2S,3S)-3-[(3-{[(1R)-1-(4-fluorophenyl)ethyl]carbamoyl}-5-[methyl(methylsulfonyl)amino]benzoyl)amino]-2-hydroxy-4-phenylbutyl}-1H-pyrazole-4-carboxylate 著者 Chen, T.T, Chen, W.Y, Xu, Y.C. 登録日 2011-11-21 公開日 2012-11-21 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Flexibility of the Flap in the Active Site of BACE1 as Revealed by Crystal Structures and MD simulations to be published
3UYI	Crystal Structure of Perakine Reductase, Founder Member of a Novel AKR Subfamily with Unique Conformational Changes during NADPH Binding 分子名称: Perakine reductase 著者 Sun, L, Chen, Y, Rajendran, C, Panjikar, S, Mueller, U, Wang, M, Rosenthal, C, Mindnich, R, Penning, T.M, Stoeckigt, J. 登録日 2011-12-06 公開日 2012-02-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.313 Å) 主引用文献 Crystal structure of perakine reductase, founding member of a novel aldo-keto reductase (AKR) subfamily that undergoes unique conformational changes during NADPH binding. J.Biol.Chem., 287, 2012
3UZX	Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and epiandrosterone 分子名称: (3Beta,5alpha)-3-Hydroxyandrostan-17-one, 3-oxo-5-beta-steroid 4-dehydrogenase, 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL, ... 著者 Chen, M, Christianson, D.W, Penning, T.M. 登録日 2011-12-07 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.637 Å) 主引用文献 Conversion of Human Steroid 5beta-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING. J.Biol.Chem., 287, 2012
3URR	Structure of PTS IIA-like nitrogen-regulatory protein PtsN (BTH_I0484) (ptsN) 分子名称: GLYCEROL, PHOSPHATE ION, PTS IIA-like nitrogen-regulatory protein PtsN 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2011-11-22 公開日 2011-12-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.397 Å) 主引用文献 Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
3V2Q	COMPcc in complex with fatty acids 分子名称: Cartilage Oligomerization matrix protein (coiled-coil domain), PALMITIC ACID 著者 Stetefeld, J. 登録日 2011-12-12 公開日 2013-01-16 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The pentameric channel of COMPcc in complex with different fatty acids. Plos One, 7, 2012
3V30	Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK 分子名称: DNA-binding protein RFX5, DNA-binding protein RFXANK 著者 Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2011-12-12 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock. Sci.Signal., 5, 2012
3UT6	Crystal structure of E. Coli PNP complexed with PO4 and formycin A 分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, PHOSPHATE ION, Purine nucleoside phosphorylase deoD-type 著者 Stefanic, Z. 登録日 2011-11-25 公開日 2012-05-23 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.895 Å) 主引用文献 New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A. Febs Lett., 586, 2012
3V3E	Crystal Structure of the Human Nur77 Ligand-binding Domain 分子名称: GLYCEROL, Nuclear receptor subfamily 4 group A member 1 著者 Zhang, Q, Shi, C, Yang, K, Chen, Y, Zhan, Y, Wu, Q, Lin, T. 登録日 2011-12-13 公開日 2012-09-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK Nat.Chem.Biol., 8, 2012
3V3T	Crystal structure of Clostridium botulinum phage c-st TubZ 分子名称: Cell division GTPase FtsZ, diverged 著者 Oliva, M.A. 登録日 2011-12-14 公開日 2012-05-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.302 Å) 主引用文献 Tubulin homolog TubZ in a phage-encoded partition system. Proc.Natl.Acad.Sci.USA, 109, 2012
3V46	Crystal Structure of Yeast Cdc73 C-Terminal Domain 分子名称: Cell division control protein 73 著者 Amrich, C.G, VanDemark, A.P. 登録日 2011-12-14 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.549 Å) 主引用文献 Cdc73 subunit of Paf1 complex contains C-terminal Ras-like domain that promotes association of Paf1 complex with chromatin. J.Biol.Chem., 287, 2012
3V4F	H-Ras PEG 400/CaCl2, ordered off 分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, CALCIUM ION, GTPase HRas, ... 著者 Holzapfel, G, Mattos, C. 登録日 2011-12-14 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.391 Å) 主引用文献 Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition. Biochemistry, 51, 2012
3UV4	Crystal Structure of the second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1) 分子名称: 1,2-ETHANEDIOL, GLYCEROL, PHOSPHATE ION, ... 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-29 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3V5O	Structural and Mechanistic Studies of Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase 分子名称: Dihydropteroate synthase, SULFATE ION 著者 Yun, M, Wu, Y, Li, Z, Zhao, Y, Waddell, M.B, Ferreira, A.M, Lee, R.E, Bashford, D, White, S.W. 登録日 2011-12-16 公開日 2012-03-14 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Catalysis and sulfa drug resistance in dihydropteroate synthase. Science, 335, 2012
3V61	Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164 分子名称: BARIUM ION, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ... 著者 Armstrong, A.A, Mohideen, F, Lima, C.D. 登録日 2011-12-18 公開日 2012-02-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2. Nature, 483, 2012
3V6C	Crystal Structure of USP2 in complex with mutated ubiquitin 分子名称: CHLORIDE ION, GLYCEROL, Ubiquitin, ... 著者 Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2011-12-19 公開日 2012-12-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal Structure of USP2 in complex with mutated ubiquitin To be Published
3UWP	Crystal structure of Dot1l in complex with 5-iodotubercidin 分子名称: (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... 著者 Yu, W, Tempel, W, Smil, D, Schapira, M, Li, Y, Vedadi, M, Nguyen, K.T, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2011-12-02 公開日 2012-03-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors. Nat Commun, 3, 2012
3UOA	Crystal structure of the MALT1 paracaspase (P21 form) 分子名称: MAGNESIUM ION, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Z-Val-Arg-Pro-DL-Arg-fluoromethylketone 著者 Jeffrey, P.D, Yu, J.W, Shi, Y. 登録日 2011-11-16 公開日 2011-12-21 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region. Proc.Natl.Acad.Sci.USA, 108, 2011
3UP3	Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-cholestenoic acid 分子名称: (8alpha,10alpha,25S)-3-hydroxycholesta-3,5-dien-26-oic acid, 1,2-ETHANEDIOL, Nuclear receptor coactivator 2, ... 著者 Zhi, X, Zhou, X.E, Melcher, K, Motola, D.L, Gelmedin, V, Hawdon, J, Kliewer, S.A, Mangelsdorf, D.J, Xu, H.E. 登録日 2011-11-17 公開日 2011-12-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural Conservation of Ligand Binding Reveals a Bile Acid-like Signaling Pathway in Nematodes. J.Biol.Chem., 287, 2012
3UZZ	Crystal structure of 5beta-reductase (AKR1D1) E120H mutant in complex with NADP+ and delta4-androstenedione 分子名称: 3-oxo-5-beta-steroid 4-dehydrogenase, 4-ANDROSTENE-3-17-DIONE, CHLORIDE ION, ... 著者 Chen, M, Christianson, D.W, Penning, T.M. 登録日 2011-12-07 公開日 2012-03-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Conversion of Human Steroid 5beta-Reductase (AKR1D1) into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H: EXAMPLE OF PERFECT ENZYME ENGINEERING. J.Biol.Chem., 287, 2012
3UPA	A general strategy for the generation of human antibody variable domains with increased aggregation resistance 分子名称: kappa light chain variable domain 著者 Dudgeon, K, Rouet, R, Kokmeijer, I, Langley, D.B, Christ, D. 登録日 2011-11-17 公開日 2012-06-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 General strategy for the generation of human antibody variable domains with increased aggregation resistance Proc.Natl.Acad.Sci.USA, 109, 2012
3UQ7	X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) mutant L240S F247L (L9S F16L) in presence of 10 mM cysteamine 分子名称: Gamma-aminobutyric-acid receptor subunit beta-1 著者 Gonzalez-Gutierrez, G, Lukk, T, Agarwal, V, Papke, D, Nair, S.K, Grosman, C. 登録日 2011-11-19 公開日 2012-04-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Proc.Natl.Acad.Sci.USA, 109, 2012
3V21	Crystal structure of Type IIF restriction endonuclease Bse634I with cognate DNA 分子名称: DNA (5'-D(*TP*TP*CP*GP*AP*CP*CP*GP*GP*TP*CP*GP*A)-3'), Endonuclease Bse634IR 著者 Manakova, E.N, Grazulis, S, Golovenko, D, Tamulaitiene, G. 登録日 2011-12-11 公開日 2012-04-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural mechanisms of the degenerate sequence recognition by Bse634I restriction endonuclease. Nucleic Acids Res., 40, 2012
3USF	Crystal structure of DAVA-4 分子名称: (4S)-4,5-DIAMINOPENTANOIC ACID, (5-HYDROXY-4,6-DIMETHYLPYRIDIN-3-YL)METHYL DIHYDROGEN PHOSPHATE, Glutamate-1-semialdehyde 2,1-aminomutase 著者 Stetefeld, J. 登録日 2011-11-23 公開日 2012-12-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.463 Å) 主引用文献 Crystal structure of DAVA-4 To be Published
3UTE	Crystal structure of Aspergillus fumigatus UDP galactopyranose mutase sulfate complex 分子名称: ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... 著者 Dhatwalia, R, Singh, H, Tanner, J.J. 登録日 2011-11-25 公開日 2012-02-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal Structures and Small-angle X-ray Scattering Analysis of UDP-galactopyranose Mutase from the Pathogenic Fungus Aspergillus fumigatus. J.Biol.Chem., 287, 2012

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