3V5O

Structural and Mechanistic Studies of Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

Summary for 3V5O

• Entry DOI: 10.2210/pdb3v5o/pdb
• Related: 1TWS
• Descriptor: Dihydropteroate synthase, SULFATE ION (3 entities in total)
• Functional Keywords: tim barrel, transferase, dhpp and paba
• Biological source: Bacillus anthracis
• Total number of polymer chains: 2
• Total formula weight: 66822.18

Authors

Yun, M.,Wu, Y.,Li, Z.,Zhao, Y.,Waddell, M.B.,Ferreira, A.M.,Lee, R.E.,Bashford, D.,White, S.W. (deposition date: 2011-12-16, release date: 2012-03-14, Last modification date: 2023-09-13)

• Primary citation: Yun, M.K.,Wu, Y.,Li, Z.,Zhao, Y.,Waddell, M.B.,Ferreira, A.M.,Lee, R.E.,Bashford, D.,White, S.W.; Catalysis and sulfa drug resistance in dihydropteroate synthase.; Science, 335:1110-1114, 2012; PubMed: 22383850; DOI: 10.1126/science.1214641

Experimental method

X-RAY DIFFRACTION (2.5 Å)