3V5O

Structural and Mechanistic Studies of Catalysis and Sulfa Drug Resistance in Dihydropteroate Synthase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Dihydropteroate synthase	polymer	297	32882.7	2	UniProt (C3P9L8)	Bacillus anthracis
2	C, D, E, F, G... (A, B)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
3	N, O (A, B)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A, B: 1 - 277 (UniProt: C3P9L8)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Asn 184	Asp 184	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65765.5
Non-Polymers*	Number of molecules	11
	Total formula weight	1056.7
All*	Total formula weight	66822.2

*Water molecules are not included.