7U3L
 
 | | GID4 in complex with compound 91 | | 分子名称: | GLYCEROL, Glucose-induced degradation protein 4 homolog, Nalpha-{(2R,4E)-2-[(N-benzylglycyl)amino]-5-phenylpent-4-enoyl}-N,4-dimethyl-L-phenylalaninamide | | 著者 | Chana, C.K, Sicheri, F. | | 登録日 | 2022-02-27 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | | 主引用文献 | Discovery and Structural Characterization of Small Molecule Binders of the Human CTLH E3 Ligase Subunit GID4.
J.Med.Chem., 65, 2022
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5FSI
 | | MTH1 substrate recognition: Complex with 8-oxo-dGTP. | | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE | | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | | 登録日 | 2016-01-06 | | 公開日 | 2016-07-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity.
Plos One, 11, 2016
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5FSK
 | | MTH1 substrate recognition: Complex with 8-oxo-dGTP. | | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, 8-OXO-ADENOSINE-5'-TRIPHOSPHATE, ACETATE ION | | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | | 登録日 | 2016-01-06 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity.
Plos One, 11, 2016
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5FSM
 | | MTH1 substrate recognition: Complex with a methylbenzimidazolyl acetamide. | | 分子名称: | 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, ACETATE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Nissink, J.W.M, Bista, M, Breed, J, Carter, N, Embrey, K, Read, J, Phillips, C, Winter, J.J. | | 登録日 | 2016-01-06 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Mth1 Substrate Recognition--an Example of Specific Promiscuity.
Plos One, 11, 2016
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3I97
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3ECV
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3ECU
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3FD7
 | | Crystal structure of Onconase C87A/C104A-ONC | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Protein P-30, ... | | 著者 | Neumann, P, Schulenburg, C, Arnold, U, Ulbrich-Hofmann, R, Stubbs, M.T. | | 登録日 | 2008-11-25 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.531 Å) | | 主引用文献 | Impact of the C-terminal disulfide bond on the folding and stability of onconase.
Chembiochem, 11, 2010
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3K0M
 | | Cryogenic structure of CypA | | 分子名称: | Cyclophilin A | | 著者 | Fraser, J.S, Alber, T. | | 登録日 | 2009-09-24 | | 公開日 | 2009-12-08 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Hidden alternative structures of proline isomerase essential for catalysis.
Nature, 462, 2009
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3K0R
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3K0P
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3K1R
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3K0N
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3K0Q
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3K7W
 | | Protein phosphatase 2A core complex bound to dinophysistoxin-2 | | 分子名称: | (2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[( 2S,6R,11S)-11-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]p yran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acid, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Jeffrey, P.D, Huhn, J, Shi, Y. | | 登録日 | 2009-10-13 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | | 主引用文献 | A structural basis for the reduced toxicity of dinophysistoxin-2.
Chem.Res.Toxicol., 22, 2009
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3KXZ
 | | The complex crystal structure of LCK with a probe molecule w259 | | 分子名称: | 3-[7-[(3-hydroxyphenyl)amino]pyrazolo[1,5-a]pyrimidin-2-yl]-N-(1-hydroxy-2,2,6,6-tetramethyl-piperidin-4-yl)benzamide, CALCIUM ION, Proto-oncogene tyrosine-protein kinase LCK, ... | | 著者 | Xu, Z.B, Moy, F.J, Kelleher, K, Mosyak, L, Protein Structure Factory (PSF) | | 登録日 | 2009-12-04 | | 公開日 | 2010-06-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance.
J.Med.Chem., 53, 2010
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3K0O
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3K7V
 | | Protein phosphatase 2A core complex bound to dinophysistoxin-1 | | 分子名称: | (2R)-3-[(2S,5R,6R,8S)-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-6'-{(1S,3S)-3-[(2S,3R,6R,11R)-3,11-dimethyl-1,7-dioxaspiro[5.5]undec-2-yl]-1-hydroxybutyl}-8'-hydroxy-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]pyran]-5-yl]-1-methylprop-2-en-1-yl}-5-hydroxy-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-hydroxy-2-methylpropanoic acid, MANGANESE (II) ION, SULFATE ION, ... | | 著者 | Jeffrey, P.D, Huhn, J, Shi, Y. | | 登録日 | 2009-10-13 | | 公開日 | 2009-11-03 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | A structural basis for the reduced toxicity of dinophysistoxin-2.
Chem.Res.Toxicol., 22, 2009
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3G7Z
 | | CcdB dimer in complex with two C-terminal CcdA domains | | 分子名称: | Cytotoxic protein ccdB, Protein ccdA | | 著者 | De Jonge, N, Loris, R, Garcia-Pino, A, Buts, L. | | 登録日 | 2009-02-11 | | 公開日 | 2009-08-11 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.351 Å) | | 主引用文献 | Rejuvenation of CcdB-Poisoned Gyrase by an Intrinsically Disordered Protein Domain.
Mol.Cell, 35, 2009
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3HNX
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3DXB
 | | Structure of the UHM domain of Puf60 fused to thioredoxin | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, thioredoxin N-terminally fused to Puf60(UHM) | | 著者 | Corsini, L, Hothorn, M, Scheffzek, K, Stier, G, Sattler, M. | | 登録日 | 2008-07-24 | | 公開日 | 2008-10-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60.
J.Biol.Chem., 284, 2009
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3FZW
 | | Crystal Structure of Ketosteroid Isomerase D40N-D103N from Pseudomonas putida (pKSI) with bound equilenin | | 分子名称: | EQUILENIN, GLYCEROL, ISOPROPYL ALCOHOL, ... | | 著者 | Caaveiro, J.M.M, Ringe, D, Petsko, G.A. | | 登録日 | 2009-01-26 | | 公開日 | 2009-06-02 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | | 主引用文献 | Hydrogen bond coupling in the ketosteroid isomerase active site.
Biochemistry, 48, 2009
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3HXG
 | | Crystal structure of Schistsome eIF4E complexed with m7GpppA and 4E-BP | | 分子名称: | Eukaryotic Translation Initiation Factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, P1-7-METHYLGUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE | | 著者 | Liu, W, Zhao, R, Jones, D.N.M, Davis, R.E. | | 登録日 | 2009-06-20 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural insights into parasite EIF4E binding specificity for m7G and m2,2,7G mRNA cap.
J.Biol.Chem., 284, 2009
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3HNU
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3H0T
 | | Hepcidin-Fab complex | | 分子名称: | Fab fragment, Heavy chain, Light chain, ... | | 著者 | Syed, R, Li, V. | | 登録日 | 2009-04-10 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Hepcidin revisited, disulfide connectivity, dynamics, and structure.
J.Biol.Chem., 284, 2009
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