3K7W
Protein phosphatase 2A core complex bound to dinophysistoxin-2
Summary for 3K7W
Entry DOI | 10.2210/pdb3k7w/pdb |
Related | 2IE4 3K7V |
Descriptor | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, SULFATE ION, ... (6 entities in total) |
Functional Keywords | protein-protein complex, heat repeat, signaling protein, phosphatase, ligand specificity, acetylation, polymorphism, centromere, cytoplasm, cytoskeleton, hydrolase, iron, manganese, metal-binding, methylation, nucleus, phosphoprotein, protein phosphatase, signaling protein-hydrolase complex, signaling protein/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Cytoplasm (By similarity): P30153 Cytoplasm: P67775 |
Total number of polymer chains | 2 |
Total formula weight | 102217.56 |
Authors | Jeffrey, P.D.,Huhn, J.,Shi, Y. (deposition date: 2009-10-13, release date: 2009-11-03, Last modification date: 2023-09-06) |
Primary citation | Huhn, J.,Jeffrey, P.D.,Larsen, K.,Rundberget, T.,Rise, F.,Cox, N.R.,Arcus, V.,Shi, Y.,Miles, C.O. A structural basis for the reduced toxicity of dinophysistoxin-2. Chem.Res.Toxicol., 22:1782-1786, 2009 Cited by PubMed: 19916524DOI: 10.1021/tx9001622 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.96 Å) |
Structure validation
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