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3K7W

Protein phosphatase 2A core complex bound to dinophysistoxin-2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformpolymer58965378.31UniProt (P30153)
Pfam (PF02985)
In PDB
Homo sapiens (human)PP2A, subunit A, PR65-alpha isoform, PP2A, subunit A, R1-alpha isoform, Medium tumor antigen-associated 61 kDa protein
2CSerine/threonine-protein phosphatase 2A catalytic subunit alpha isoformpolymer30935636.21UniProt (P67775)
Pfam (PF00149)
In PDB
Homo sapiens (human)PP2A-alpha, Replication protein C, RP-C
3A, CSULFATE IONnon-polymer96.13Chemie (SO4)
4C(2R)-2-hydroxy-3-[(2S,5R,6R,8S)-5-hydroxy-8-{(1R,2E)-3-[(2R,4a'R,5R,6'S,8'R,8a'S)-8'-hydroxy-6'-{(1S,3S)-1-hydroxy-3-[( 2S,6R,11S)-11-methyl-1,7-dioxaspiro[5.5]undec-2-yl]butyl}-7'-methylideneoctahydro-3H,3'H-spiro[furan-2,2'-pyrano[3,2-b]p yran]-5-yl]-1-methylprop-2-en-1-yl}-10-methyl-1,7-dioxaspiro[5.5]undec-10-en-2-yl]-2-methylpropanoic acidnon-polymer805.01Chemie (XT2)
5CMANGANESE (II) IONnon-polymer54.92Chemie (MN)
6waterwater18.025Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight101014.5
Non-Polymers*Number of molecules6
Total formula weight1203.1
All*Total formula weight102217.6
*Water molecules are not included.

221051

PDB entries from 2024-06-12

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