5IDM
 
 | | Bifunctional histidine kinase CckA (domain, CA) in complex with c-di-GMP and AMPPNP/Mg2+ | | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Cell cycle histidine kinase CckA, MAGNESIUM ION, ... | | 著者 | Dubey, B.N, Schirmer, T. | | 登録日 | 2016-02-24 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking.
Sci Adv, 2, 2016
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6SBJ
 | | X-ray structure of mus musculus Fumarylacetoacetate hydrolase domain containing protein 1 (FAHD1) apo-form uuncomplexed | | 分子名称: | Acylpyruvase FAHD1, mitochondrial, CHLORIDE ION, ... | | 著者 | Rupp, B, Naschberger, A, Weiss, A.K.H. | | 登録日 | 2019-07-21 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural and functional comparison of fumarylacetoacetate domain containing protein 1 in human and mouse.
Biosci.Rep., 40, 2020
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6ME5
 | | XFEL crystal structure of human melatonin receptor MT1 in complex with agomelatine | | 分子名称: | OLEIC ACID, chimera protein of Melatonin receptor type 1A and GlgA glycogen synthase, ~{N}-[2-(7-methoxynaphthalen-1-yl)ethyl]ethanamide | | 著者 | Stauch, B, Johansson, L.C, McCorvy, J.D, Patel, N, Han, G.W, Gati, C, Batyuk, A, Ishchenko, A, Brehm, W, White, T.A, Michaelian, N, Madsen, C, Zhu, L, Grant, T.D, Grandner, J.M, Olsen, R.H.J, Tribo, A.R, Weierstall, U, Roth, B.L, Katritch, V, Liu, W, Cherezov, V. | | 登録日 | 2018-09-05 | | 公開日 | 2019-04-24 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis of ligand recognition at the human MT1melatonin receptor.
Nature, 569, 2019
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8D9D
 | | Human DNA polymerase-alpha/primase elongation complex II bound to primer/template | | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*TP*GP*GP*TP*CP*GP*TP*GP*CP*CP*GP*CP*CP*AP*AP*TP*AP*A)-3'), DNA polymerase alpha catalytic subunit, ... | | 著者 | He, Q, Baranovskiy, A, Lim, C, Tahirov, T. | | 登録日 | 2022-06-09 | | 公開日 | 2023-04-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structures of human primosome elongation complexes.
Nat.Struct.Mol.Biol., 30, 2023
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6PB4
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6GVN
 | | Tubulin:TM-3 DARPin complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Gigant, B, Cantos Fernandes, S, Campanacci, V. | | 登録日 | 2018-06-21 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Insight into microtubule nucleation from tubulin-capping proteins.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8DJJ
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8DI3
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8DKK
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6GXA
 | | Crystal structure of Schistosoma mansoni HDAC8 complexed with an hydroxamate 2 | | 分子名称: | (~{E})-3-(2-chlorophenyl)-~{N}-oxidanyl-prop-2-enamide, DIMETHYLFORMAMIDE, GLYCEROL, ... | | 著者 | Shaik, T.B, Marek, M, Romier, C. | | 登録日 | 2018-06-27 | | 公開日 | 2018-08-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Synthesis, Crystallization Studies, and in vitro Characterization of Cinnamic Acid Derivatives as SmHDAC8 Inhibitors for the Treatment of Schistosomiasis.
ChemMedChem, 13, 2018
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6B0E
 | | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 | | 分子名称: | 1260 antibody, heavy chain, light chain, ... | | 著者 | Scally, S.W, McLeod, B, Bosch, A, King, C.R, Julien, J.P. | | 登録日 | 2017-09-14 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Molecular definition of multiple sites of antibody inhibition of malaria transmission-blocking vaccine antigen Pfs25.
Nat Commun, 8, 2017
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5IM4
 | | Crystal structure of designed two-component self-assembling icosahedral cage I52-32 | | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA | | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | | 登録日 | 2016-03-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
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5IPM
 | | SigmaS-transcription initiation complex with 4-nt nascent RNA | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Liu, B, Zuo, Y, Steitz, T.A. | | 登録日 | 2016-03-09 | | 公開日 | 2016-03-30 | | 最終更新日 | 2016-06-22 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism.
Proc.Natl.Acad.Sci.USA, 113, 2016
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8DKH
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8DKJ
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7B2T
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8D0O
 | | Human alpha1,3-fucosyltransferase FUT9, heavy atom derivative | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase 9, CESIUM ION, ... | | 著者 | Kadirvelraj, R, Wood, Z.A. | | 登録日 | 2022-05-26 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for Lewis antigen synthesis by the alpha 1,3-fucosyltransferase FUT9.
Nat.Chem.Biol., 19, 2023
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8TFR
 | | Apo Fab from C10-S66K antibody | | 分子名称: | Heavy chain from Fab of C10_S66K antibody, Immunoglobulin G-binding protein G, Light chain from Fab of C10_S66K antibody | | 著者 | Pholcharee, T, Wilson, I.A. | | 登録日 | 2023-07-11 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | An Engineered Human-Antibody Fragment with Fentanyl Pan-Specificity That Reverses Carfentanil-Induced Respiratory Depression.
Acs Chem Neurosci, 14, 2023
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5EUV
 | | Crystal structure of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d strain | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Beta-D-galactosidase, ... | | 著者 | Rutkiewicz-Krotewicz, M, Bujacz, A, Pietrzyk, A.J, Sekula, B, Bujacz, G. | | 登録日 | 2015-11-19 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural studies of a cold-adapted dimeric beta-D-galactosidase from Paracoccus sp. 32d.
Acta Crystallogr D Struct Biol, 72, 2016
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7OIT
 | | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (P3221 crystal form) | | 分子名称: | AP-2 complex subunit mu, F-BAR domain only protein 2, GLYCEROL | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-12 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OG1
 | | AP2 clathrin adaptor core in complex with cargo peptide and FCHO2 | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-05 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OHO
 | | Crystal structure of AP2 FCHO2 chimera | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta,F-BAR domain only protein 2, AP-2 complex subunit mu, ... | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-11 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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7OIQ
 | | Crystal structure of AP2 Mu2 in complex with FCHO2 WxxPhi motif (C2 crystal form) | | 分子名称: | AP-2 complex subunit mu, F-BAR domain only protein 2 | | 著者 | Zaccai, N.R, Kelly, B.T, Evans, P.R, Owen, D.J. | | 登録日 | 2021-05-12 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Sci Adv, 8, 2022
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5U0U
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7NRU
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