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6LND
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Crystal structure of transposition protein TniQ
分子名称: ZINC ION, transposition protein TniQ
著者Wang, B, Xu, W, Yang, H.
登録日2019-12-28
公開日2020-02-19
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis of a Tn7-like transposase recruitment and DNA loading to CRISPR-Cas surveillance complex.
Cell Res., 30, 2020
1ENN
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BU of 1enn by Molmil
SOLVENT ORGANIZATION IN AN OLIGONUCLEOTIDE CRYSTAL: THE STRUCTURE OF D(GCGAATTCG)2 AT ATOMIC RESOLUTION
分子名称: CHLORIDE ION, DNA (5'-D(*GP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MAGNESIUM ION, ...
著者Soler-Lopez, M, Malinina, L, Subirana, J.A.
登録日2000-03-21
公開日2000-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献Solvent organization in an oligonucleotide crystal. The structure of d(GCGAATTCG)2 at atomic resolution.
J.Biol.Chem., 275, 2000
380D
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BU of 380d by Molmil
BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES
分子名称: 2'-BROMO-4'-EPIDAUNORUBICIN, DNA (5'-D(*CP*GP*(G49)P*(CBR)P*CP*G)-3')
著者Dutta, R, Gao, Y.-G, Priebe, W, Wang, A.H.-J.
登録日1998-02-18
公開日1998-07-13
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.
Nucleic Acids Res., 26, 1998
6EXT
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BU of 6ext by Molmil
Crystal structure of the DNA binding domain of fission yeast Sap1
分子名称: Switch-activating protein 1
著者Ekundayo, B, Joergensen, M, Schalch, T.
登録日2017-11-09
公開日2018-11-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the replication regulator Sap1 reveals functionally important interfaces.
Sci Rep, 8, 2018
2I5J
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BU of 2i5j by Molmil
Crystal structure of HIV-1 reverse transcriptase (RT) in complex with DHBNH, an RNASE H inhibitor
分子名称: (E)-3,4-DIHYDROXY-N'-[(2-METHOXYNAPHTHALEN-1-YL)METHYLENE]BENZOHYDRAZIDE, MAGNESIUM ION, Reverse transcriptase/ribonuclease H P51 subunit, ...
著者Himmel, D.M, Sarafianos, S.G, Knight, J.L, Levy, R.M, Arnold, E.
登録日2006-08-24
公開日2006-12-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献HIV-1 reverse transcriptase structure with RNase H inhibitor dihydroxy benzoyl naphthyl hydrazone bound at a novel site.
Acs Chem.Biol., 1, 2006
6EXU
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BU of 6exu by Molmil
Crystal structure of the DNA binding domain of fission yeast Sap1
分子名称: Switch-activating protein 1
著者Ekundayo, B, Joergensen, M, Schalch, T.
登録日2017-11-09
公開日2018-11-28
実験手法X-RAY DIFFRACTION (1.409 Å)
主引用文献Structure of the replication regulator Sap1 reveals functionally important interfaces.
Sci Rep, 8, 2018
7N9H
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BU of 7n9h by Molmil
Structure of the mammalian importin a1 bound to the TDP-43 NLS
分子名称: Importin subunit alpha-1, TAR DNA-binding protein 43
著者Doll, S.G, Lokareddy, R.K, Cingolani, G.
登録日2021-06-17
公開日2022-06-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of the TDP-43 nuclear localization signal by importin alpha 1/ beta.
Cell Rep, 39, 2022
482D
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BU of 482d by Molmil
RELEASE OF THE CYANO MOIETY IN THE CRYSTAL STRUCTURE OF N-CYANOMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN COMPLEXED WITH D(CGATCG)
分子名称: 5'-D(*CP*GP*AP*TP*CP*G)-3', N-HYDROXYMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN
著者Saminadin, P, Dautant, A, Mondon, M, Langlois D'Estaintot, B, Courseille, C, Precigoux, G.
登録日1999-07-27
公開日1999-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG).
Eur.J.Biochem., 267, 2000
3HQG
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BU of 3hqg by Molmil
Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA
分子名称: 5'-D(*TP*AP*GP*CP*CP*TP*GP*GP*TP*CP*GP*A)-3', 5'-D(*TP*CP*GP*AP*CP*CP*AP*GP*GP*CP*TP*A)-3', GLYCEROL, ...
著者Golovenko, D, Manakova, E, Grazulis, S, Tamulaitiene, G, Siksnys, V.
登録日2009-06-06
公開日2009-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII.
Nucleic Acids Res., 37, 2009
3QMH
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BU of 3qmh by Molmil
Structural Basis of Selective Binding of Non-Methylated CpG islands (DNA-TCGA) by the CXXC Domain of CFP1
分子名称: 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', CpG-binding protein, ZINC ION
著者Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2011-02-04
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
2AQY
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(3+1) assembly of three human telomeric DNA repeats into an asymmetrical dimeric G-quadruplex
分子名称: 5'-D(*GP*(OIP)P*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*T)-3', 5'-D(*TP*AP*GP*GP*GP*(DU))-3'
著者Zhang, N, Phan, A.T, Patel, D.J.
登録日2005-08-18
公開日2006-03-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献(3 + 1) Assembly of three human telomeric repeats into an asymmetric dimeric G-quadruplex
J.Am.Chem.Soc., 127, 2005
4DM0
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BU of 4dm0 by Molmil
TN5 transposase: 20MER OUTSIDE END 2 MN complex
分子名称: 1,2-ETHANEDIOL, DNA NON-TRANSFERRED STRAND, DNA TRANSFERRED STRAND, ...
著者Klenchin, V.A, Lovell, S, Goryshin, I.Y, Reznikoff, W.R, Rayment, I.
登録日2012-02-06
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two-metal active site binding of a TN5 transposase synaptic complex
Nat.Struct.Biol., 9, 2002
8UMF
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BU of 8umf by Molmil
Structure of PsCas9 in complex with gRNA and DNA in product state
分子名称: Cas9, DNA (80-MER), MAGNESIUM ION, ...
著者Bravo, J.P.K, Taylor, D.W.
登録日2023-10-17
公開日2024-10-02
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structure-guided engineering of PsCas9 yields a high fidelity and activity enzyme for in vivo gene editing
To Be Published
6W11
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BU of 6w11 by Molmil
The structure of Sulfolobus solfataricus Csa3 in complex with cyclic tetraadenylate (cA4)
分子名称: CRISPR locus-related putative DNA-binding protein Csa3, cA4
著者Charbonneau, A.A, Gauvin, C.C, Lawrence, C.M.
登録日2020-03-03
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Cyclic Tetra-Adenylate (cA 4 ) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus.
Biomolecules, 11, 2021
2O3M
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BU of 2o3m by Molmil
Monomeric G-DNA tetraplex from human C-kit promoter
分子名称: 5'-D(*AP*GP*GP*GP*AP*GP*GP*GP*CP*GP*CP*TP*GP*GP*GP*AP*GP*GP*AP*GP*GP*G)-3'
著者Phan, A.T, Kuryavyi, V.V, Burge, S, Neidle, S, Patel, D.J.
登録日2006-12-01
公開日2007-05-22
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of an unprecedented G-quadruplex scaffold in the human c-kit promoter.
J.Am.Chem.Soc., 129, 2007
8FDR
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BU of 8fdr by Molmil
Structure of a dodecamer complex: 5'-CGCGAAAAGCCG-3-DB1476
分子名称: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*TP*TP*TP*CP*GP*CP*G)-3'), ...
著者Ogbonna, E, Wilson, W.D.
登録日2022-12-04
公開日2023-02-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
4N0O
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BU of 4n0o by Molmil
Complex structure of Arterivirus nonstructural protein 10 (helicase) with DNA
分子名称: CALCIUM ION, DNA, Replicase polyprotein 1ab, ...
著者Deng, Z, Chen, Z.
登録日2013-10-02
公開日2014-01-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase.
Nucleic Acids Res., 42, 2014
1Y84
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BU of 1y84 by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(imidazolyl)ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(EIT)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-10
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1Y86
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Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(fluoro)ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3'
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-10
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1LAI
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Solution Structure of the B-DNA Duplex CGCGGTGTCCGCG.
分子名称: 5'-D(*CP*GP*CP*GP*GP*AP*CP*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*GP*TP*CP*CP*GP*CP*G)-3'
著者Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P.
登録日2002-03-28
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15, 2002
1LAQ
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Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C2' Endo Conformation.
分子名称: 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3'
著者Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P.
登録日2002-03-29
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15, 2002
1Y7F
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Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-[hydroxy(methyleneamino)oxy]ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(2NT)P*AP*CP*GP*C)-3'), BARIUM ION
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-08
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1LAS
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BU of 1las by Molmil
Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C3' Endo Conformation.
分子名称: 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3'
著者Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P.
登録日2002-03-29
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15, 2002
3QMD
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Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
分子名称: CpG-binding protein, DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*AP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*CP*GP*TP*TP*GP*GP*C)-3'), ...
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-02-04
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
2HKB
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NMR Structure of the B-DNA Dodecamer CTCGGCGCCATC
分子名称: 5'-D(*CP*TP*CP*GP*GP*CP*GP*CP*CP*AP*TP*C)-3', 5'-D(*GP*AP*TP*GP*GP*CP*GP*CP*CP*GP*AP*G)-3'
著者Wang, F, DeMuro, N.E, Elmquist, C.E, Stover, J.S, Rizzo, C.J, Stone, M.P.
登録日2006-07-03
公開日2006-10-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Base-displaced intercalated structure of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in the recognition sequence of the NarI restriction enzyme, a hotspot for -2 bp deletions.
J.Am.Chem.Soc., 128, 2006

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