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4C63
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ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA WITH 5- METHYLCYSTOSINE MODIFICATION
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*5CMP*GP*CP*GP)-3', MAGNESIUM ION
著者Mcdonough, M, El-Sagheer, A.H, Brown, T, Schofield, C.J.
登録日2013-09-17
公開日2013-10-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural insights into how 5-hydroxymethylation influences transcription factor binding.
Chem. Commun. (Camb.), 50, 2014
6RIX
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BU of 6rix by Molmil
Crystal structure of MchDnaB-1 intein
分子名称: CHLORIDE ION, Replicative DNA helicase
著者Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
登録日2019-04-25
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.655 Å)
主引用文献The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
3VA0
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BU of 3va0 by Molmil
Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site
分子名称: COBALT (II) ION, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ...
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2011-12-28
公開日2012-07-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.201 Å)
主引用文献How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
2MZQ
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BU of 2mzq by Molmil
NMR structure of the RRM3 domain of Gbp2
分子名称: Single-strand telomeric DNA-binding protein GBP2
著者Martinez-Lumbreras, S, Seraphin, B, Perez-Canadillas, J.
登録日2015-02-23
公開日2015-12-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Gbp2 interacts with THO/TREX through a novel type of RRM domain.
Nucleic Acids Res., 44, 2016
2VPV
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BU of 2vpv by Molmil
Dimerization Domain of Mif2p
分子名称: PROTEIN MIF2, SULFATE ION
著者Cohen, R.L, Espelin, C.W, Sorger, P.K, Harrison, S.C, Simons, K.T.
登録日2008-03-05
公開日2008-08-26
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and Functional Dissection of Mif2P, a Conserved DNA-Binding Kinetochore Protein.
Mol.Biol.Cell, 19, 2008
8PJ9
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BU of 8pj9 by Molmil
Cas9 bound to cognate DNA, Streptococcus thermophilus DGCC 7710 CRISPR3 system
分子名称: CRISPR-associated endonuclease Cas9, DNA oligoduplex, non-target strand, ...
著者Sasnauskas, G, Gaizauskaite, U, Tamulaitiene, G.
登録日2023-06-23
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.24 Å)
主引用文献Structural basis for spacer acquisition in a type II-A CRISPR-Cas system
To Be Published
8D2K
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BU of 8d2k by Molmil
Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 2)
分子名称: CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ...
著者Rai, J, Das, A, Li, H.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.43 Å)
主引用文献Coupled catalytic states and the role of metal coordination in Cas9.
Nat Catal, 6, 2023
8D2L
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Structure of Acidothermus cellulolyticus Cas9 ternary complex (Cleavage Intermediate 1)
分子名称: CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*GP*A)-3'), ...
著者Rai, J, Das, A, Li, H.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.21 Å)
主引用文献Coupled catalytic states and the role of metal coordination in Cas9.
Nat Catal, 6, 2023
4Z0C
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BU of 4z0c by Molmil
Crystal structure of TLR13-ssRNA13 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DNA (5'-R(P*AP*CP*GP*GP*AP*AP*AP*GP*AP*CP*CP*CP*C)-3'), ...
著者Song, W, Han, Z, Chai, J.
登録日2015-03-26
公開日2015-10-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13
Nat.Struct.Mol.Biol., 22, 2015
6RIY
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BU of 6riy by Molmil
Crystal structure of MchDnaB-1 intein (N145AA)
分子名称: CHLORIDE ION, Replicative DNA helicase
著者Beyer, H.M, Lountos, G.T, Mikula, M.K, Wlodawer, A, Iwai, H.
登録日2019-04-25
公開日2020-05-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The Convergence of the Hedgehog/Intein Fold in Different Protein Splicing Mechanisms.
Int J Mol Sci, 21, 2020
8EC1
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BU of 8ec1 by Molmil
5'-CGCGAATTCGCG-3' and benzimidazole diamidine (DB1476) comlpex with ligand orientation I
分子名称: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), MAGNESIUM ION
著者Ogbonna, E.N, Wilson, W.D.
登録日2022-08-31
公開日2023-02-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
2CN5
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BU of 2cn5 by Molmil
Crystal structure of human Chk2 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, MAGNESIUM ION, ...
著者Oliver, A.W, Pearl, L.H.
登録日2006-05-18
公開日2006-06-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Trans-Activation of the DNA-Damage Signalling Protein Kinase Chk2 by T-Loop Exchange
Embo J., 25, 2006
1JHI
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BU of 1jhi by Molmil
Solution Structure of a Hedamycin-DNA complex
分子名称: 5'-D(*AP*CP*CP*(HEH)GP*GP*T)-3', HEDAMYCIN
著者Owen, E.A, Burley, G.A, Carver, J.A, Wickham, G, Keniry, M.A.
登録日2001-06-27
公開日2003-07-08
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural investigation of the hedamycin:d(ACCGGT)2 complex by NMR and restrained molecular dynamics.
Biochem.Biophys.Res.Commun., 290, 2002
1MOW
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BU of 1mow by Molmil
E-DreI
分子名称: 5'-D(*CP*CP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*AP*GP*TP*TP*CP*CP*GP*GP*CP*G)-3', 5'-D(*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*GP*G)-3', GLYCEROL, ...
著者Chevalier, B.S, Kortemme, T, Chadsey, M.S, Baker, D, Monnat Jr, R.J, Stoddard, B.L.
登録日2002-09-10
公開日2002-11-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Design, Activity and Structure of a Highly Specific Artificial Endonuclease
Mol.Cell, 10, 2002
8CFA
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BU of 8cfa by Molmil
HK97 Prohead II as part of a DNA packaging complex
分子名称: Major capsid subunit
著者Hawkins, D.E.D.P, Antson, A.A.
登録日2023-02-03
公開日2023-05-24
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.06 Å)
主引用文献Insights into a viral motor: the structure of the HK97 packaging termination assembly.
Nucleic Acids Res., 51, 2023
4D6O
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BU of 4d6o by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MG (STATE 2)
分子名称: 25MER, ACETATE ION, HOMING ENDONUCLEASE I-DMOI, ...
著者Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G.
登録日2014-11-13
公開日2014-12-17
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease.
Nat.Struct.Mol.Biol., 22, 2015
4HQX
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BU of 4hqx by Molmil
CRYSTAL STRUCTURE OF HUMAN PDGF-BB IN COMPLEX WITH A Modified nucleotide aptamer (SOMAmer SL4)
分子名称: MAGNESIUM ION, Platelet-derived growth factor subunit B, SODIUM ION, ...
著者Davies, D.R, Edwards, T.E, Janjic, N, Gelinas, A.D, Zhang, C, Jarvis, T.C.
登録日2012-10-26
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
4HQU
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BU of 4hqu by Molmil
Crystal structure of human PDGF-BB in complex with a modified nucleotide aptamer (SOMAmer SL5)
分子名称: MAGNESIUM ION, Platelet-derived growth factor subunit B, SODIUM ION, ...
著者Davies, D.R, Edwards, T.E, Janjic, N, Gelinas, A.D, Zhang, C, Jarvis, T.C.
登録日2012-10-26
公開日2012-11-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets.
Proc.Natl.Acad.Sci.USA, 109, 2012
1T0F
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BU of 1t0f by Molmil
Crystal Structure of the TnsA/TnsC(504-555) complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, MAGNESIUM ION, MALONIC ACID, ...
著者Ronning, D.R, Li, Y, Perez, Z.N, Ross, P.D, Hickman, A.B, Craig, N.L, Dyda, F.
登録日2004-04-08
公開日2004-11-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The carboxy-terminal portion of TnsC activates the Tn7 transposase through a specific interaction with TnsA.
Embo J., 23, 2004
4C64
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BU of 4c64 by Molmil
ULTRA HIGH RESOLUTION DICKERSON-DREW DODECAMER B-DNA
分子名称: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*GP)-3', MAGNESIUM ION
著者Mcdonough, M, El-Sagheer, A.H, Brown, T, Schofield, C.J.
登録日2013-09-17
公開日2013-10-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural insights into how 5-hydroxymethylation influences transcription factor binding.
Chem. Commun. (Camb.), 50, 2014
5AK9
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BU of 5ak9 by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF 2MM MN
分子名称: 25MER, 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', 5'-D(*GP*TP*TP*CP*CP*GP*GP*CP*GP*CP*GP)-3, ...
著者Molina, R, Marcaida, M.J, Redondo, P, Marenchino, M, D'Abramo, M, Montoya, G, Prieto, J.
登録日2015-03-02
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
5AKM
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BU of 5akm by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI G20S IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF 2MM MG
分子名称: 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*CP)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*CP)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', ...
著者Molina, R, Marcaida, M.J, Redondo, P, Marenchino, M, D'Abramo, M, Montoya, G, Prieto, J.
登録日2015-03-04
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
7V99
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catalytic core of human telomerase holoenzyme
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Primer DNA, ...
著者Wan, F, Ding, Y, Yang, L, Wu, Z, Wu, J, Lei, M.
登録日2021-08-24
公開日2022-03-30
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Zipper head mechanism of telomere synthesis by human telomerase.
Cell Res., 31, 2021
8D2O
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BU of 8d2o by Molmil
Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 2)
分子名称: CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ...
著者Rai, J, Das, A, Li, H.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Coupled catalytic states and the role of metal coordination in Cas9.
Nat Catal, 6, 2023
8D2Q
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Structure of Acidothermus cellulolyticus Cas9 ternary complex (Post-cleavage 1)
分子名称: CRISPR-associated endonuclease, Csn1 family, DNA non-target strand (5'-D(P*AP*TP*AP*CP*AP*CP*CP*AP*AP*GP*CP*T)-3'), ...
著者Rai, J, Das, A, Li, H.
登録日2022-05-30
公開日2023-12-20
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Coupled catalytic states and the role of metal coordination in Cas9.
Nat Catal, 6, 2023

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