8EC1

5'-CGCGAATTCGCG-3' and benzimidazole diamidine (DB1476) comlpex with ligand orientation I

Summary for 8EC1

• Entry DOI: 10.2210/pdb8ec1/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3'), 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: b-dna, minor groove, small molecule, dna
• Biological source: Homo
• Total number of polymer chains: 2
• Total formula weight: 7705.50

Authors

Ogbonna, E.N.,Wilson, W.D. (deposition date: 2022-08-31, release date: 2023-02-22, Last modification date: 2023-08-30)

• Primary citation: Ogbonna, E.N.,Paul, A.,Farahat, A.A.,Terrell, J.R.,Mineva, E.,Ogbonna, V.,Boykin, D.W.,Wilson, W.D.; X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.; Acs Bio Med Chem Au, 3:335-348, 2023; PubMed: 37599788; DOI: 10.1021/acsbiomedchemau.3c00002

Experimental method

X-RAY DIFFRACTION (1.63 Å)