1SL6
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![BU of 1sl6 by Molmil](/molmil-images/mine/1sl6) | Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x. | 分子名称: | C-type lectin DC-SIGNR, CALCIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K. | 登録日 | 2004-03-05 | 公開日 | 2004-06-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for distinct ligand-binding and targeting properties of the receptors
DC-SIGN and DC-SIGNR Nat.Struct.Mol.Biol., 11, 2004
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7ADV
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![BU of 7adv by Molmil](/molmil-images/mine/7adv) | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ447 (compound 6v) | 分子名称: | 4-azanyl-~{N}-[[2,4-bis(fluoranyl)phenyl]methyl]-6-[2-(2-morpholin-4-ylethylsulfonyl)ethyl]-1-oxidanyl-2-oxidanylidene-1,8-naphthyridine-3-carboxamide, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... | 著者 | Pye, V.E, Cherepanov, P. | 登録日 | 2020-09-16 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | HIV-1 Integrase Inhibitors with Modifications That Affect Their Potencies against Drug Resistant Integrase Mutants. Acs Infect Dis., 7, 2021
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8C5I
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![BU of 8c5i by Molmil](/molmil-images/mine/8c5i) | Cyanide dihydratase from Bacillus pumilus C1 variant - Q86R,H305K,H308K,H323K | 分子名称: | Cyanide dihydratase | 著者 | Mulelu, A.E, Reitz, J, van Rooyen, J, Scheffer, M, Frangakis, A.S, Dlamini, L.S, Woodward, J.D, Benedik, M.J, Sewell, B.T. | 登録日 | 2023-01-09 | 公開日 | 2023-01-18 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | The Role of Histidine Residues in the Oligomerization of Cyanide Dihydratase from Bacillus pumilus C1 To Be Published
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6OU3
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7ACK
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![BU of 7ack by Molmil](/molmil-images/mine/7ack) | CDK2/cyclin A2 in complex with an imidazo[1,2-c]pyrimidin-5-one inhibitor | 分子名称: | 1,2-ETHANEDIOL, 8-cyclohexyl-6~{H}-imidazo[1,2-c]pyrimidin-5-one, Cyclin-A2, ... | 著者 | Skerlova, J, Pachl, P, Rezacova, P. | 登録日 | 2020-09-11 | 公開日 | 2021-03-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure. Eur.J.Med.Chem., 216, 2021
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5EA4
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![BU of 5ea4 by Molmil](/molmil-images/mine/5ea4) | Crystal Structure of Inhibitor JNJ-49153390 in Complex with Prefusion RSV F Glycoprotein | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 3-[[5-bromanyl-1-(3-methylsulfonylpropyl)benzimidazol-2-yl]methyl]-1-cyclopropyl-imidazo[4,5-c]pyridin-2-one, Fusion glycoprotein F0, ... | 著者 | Battles, M.B, McLellan, J.S, Arnoult, E, Roymans, D, Langedijk, J.P. | 登録日 | 2015-10-15 | 公開日 | 2015-12-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanism of respiratory syncytial virus fusion inhibitors. Nat.Chem.Biol., 12, 2016
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1N46
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![BU of 1n46 by Molmil](/molmil-images/mine/1n46) | CRYSTAL STRUCTURE OF HUMAN TR BETA LIGAND-BINDING DOMAIN COMPLEXED WITH A POTENT SUBTYPE-SELECTIVE THYROMIMETIC | 分子名称: | Thyroid hormone receptor Beta-1, [4-(4-HYDROXY-3-ISOPROPYL-PHENOXY)-3,5-DIMETHYL-PHENYL]-6-AZAURACIL | 著者 | Dow, R.L, Schneider, S.R, Paight, E.S, Hank, R.F, Chiang, P, Cornelius, P, Lee, E, Newsome, W.P, Swick, A.G, Spitzer, J, Hargrove, D.M, Patterson, T.A, Pandit, J, Chrunyk, B.A, LeMotte, P.K, Danley, D.E, Rosner, M.H, Ammirati, M.J, Simons, S.P, Schulte, G.K, Tate, B.F, DaSilva-Jardine, P. | 登録日 | 2002-10-30 | 公開日 | 2003-04-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Novel Series of 6-Azauracil-Based Thyroid Hormone Receptor Ligands:
Potent, TRbeta Subtype-Selective Thyromimetics Bioorg.Med.Chem.Lett., 13, 2003
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7ADU
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1WEJ
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![BU of 1wej by Molmil](/molmil-images/mine/1wej) | IGG1 FAB FRAGMENT (OF E8 ANTIBODY) COMPLEXED WITH HORSE CYTOCHROME C AT 1.8 A RESOLUTION | 分子名称: | CYTOCHROME C, E8 ANTIBODY, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Mylvaganam, S.E, Paterson, Y, Getzoff, E.D. | 登録日 | 1998-03-26 | 公開日 | 1998-12-09 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolution. J.Mol.Biol., 281, 1998
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6UGL
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![BU of 6ugl by Molmil](/molmil-images/mine/6ugl) | VqmA bound to DPO | 分子名称: | 3,5-dimethylpyrazin-2(1H)-one, Helix-turn-helix transcriptional regulator | 著者 | Paczkowski, J.E, Huang, X. | 登録日 | 2019-09-26 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Mechanism underlying autoinducer recognition in theVibrio choleraeDPO-VqmA quorum-sensing pathway. J.Biol.Chem., 295, 2020
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7A10
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![BU of 7a10 by Molmil](/molmil-images/mine/7a10) | LppS with covalent adduct derived from 1g | 分子名称: | 4-methoxycyclohexa-2,5-diene-1-thione, L,D-transpeptidase 2 | 著者 | Schnell, R, Steiner, E.M. | 登録日 | 2020-08-11 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A0Z
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![BU of 7a0z by Molmil](/molmil-images/mine/7a0z) | LppS with covalent adduct derived from 1b | 分子名称: | L,D-transpeptidase 2, TRIS(HYDROXYETHYL)AMINOMETHANE, benzenethiol | 著者 | Schnell, R, Steiner, E.M. | 登録日 | 2020-08-11 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A1E
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![BU of 7a1e by Molmil](/molmil-images/mine/7a1e) | LppS with covalent adduct derived from 1c | 分子名称: | ACETATE ION, L,D-transpeptidase 2, phenylmethanethiol | 著者 | Schnell, R, Steiner, E.M. | 登録日 | 2020-08-12 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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7A1C
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1AAT
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7A11
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![BU of 7a11 by Molmil](/molmil-images/mine/7a11) | LppS with covalent adduct derived from 1E | 分子名称: | ACETATE ION, L,D-transpeptidase 2, propane-1-thiol | 著者 | Schnell, R, Steiner, E.M. | 登録日 | 2020-08-11 | 公開日 | 2021-04-21 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | N-Thio-beta-lactams targeting L,D-transpeptidase-2, with activity against drug-resistant strains of Mycobacterium tuberculosis. Cell Chem Biol, 28, 2021
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5EO9
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![BU of 5eo9 by Molmil](/molmil-images/mine/5eo9) | Crystal Structure of the complex of Dpr6 Domain 1 bound to DIP-alpha Domain 1+2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CG32791, isoform A, ... | 著者 | Ozkan, E, Zinn, K, Garcia, K.C. | 登録日 | 2015-11-10 | 公開日 | 2016-01-06 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.2988 Å) | 主引用文献 | Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. Cell, 163, 2015
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2DB4
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![BU of 2db4 by Molmil](/molmil-images/mine/2db4) | Crystal structure of rotor ring with DCCD of the V- ATPase from Enterococcus hirae | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, DICYCLOHEXYLUREA, SODIUM ION, ... | 著者 | Murata, T, Yamato, I, Kakinuma, Y, Shirouzu, M, Walker, J.E, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2005-12-15 | 公開日 | 2006-12-05 | 最終更新日 | 2012-05-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the rotor ring modified with N,N'-dicyclohexylcarbodiimide of the Na+-transporting vacuolar ATPase. Proc.Natl.Acad.Sci.USA, 108, 2011
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8TF3
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![BU of 8tf3 by Molmil](/molmil-images/mine/8tf3) | Wildtype rabbit TRPV5 into nanodiscs in complex with econazole | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, ERGOSTEROL, ... | 著者 | De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y. | 登録日 | 2023-07-07 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural mechanism of TRPV5 inhibition by econazole. Structure, 32, 2024
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6OEE
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![BU of 6oee by Molmil](/molmil-images/mine/6oee) | Structure of CagT from a cryo-EM reconstruction of a T4SS | 分子名称: | Type IV secretion system apparatus protein CagT | 著者 | Chung, J.M, Sheedlo, M.J, Campbell, A, Sawhney, N, Frick-Cheng, A.E, Lacy, D.B, Cover, T.L, Ohi, M.D. | 登録日 | 2019-03-27 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the Helicobacter pylori Cag type IV secretion system. Elife, 8, 2019
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8CK0
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3E40
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![BU of 3e40 by Molmil](/molmil-images/mine/3e40) | Q138F HincII bound to GTTAAC and cocrystallized with 5 mM Ca2+ | 分子名称: | 5'-D(*DGP*DCP*DCP*DGP*DGP*DTP*DP*DAP*DAP*DCP*DCP*DGP*DGP*DC)-3'), CALCIUM ION, SODIUM ION, ... | 著者 | Horton, N.C, Babic, A.C, Little, E.J, Manohar, V.M. | 登録日 | 2008-08-08 | 公開日 | 2008-08-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | DNA distortion and specificity in a sequence-specific endonuclease. J.Mol.Biol., 383, 2008
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8TF2
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8TF4
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![BU of 8tf4 by Molmil](/molmil-images/mine/8tf4) | Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and econazole | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(2S)-2-[(4-CHLOROBENZYL)OXY]-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE, ERGOSTEROL, ... | 著者 | De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y. | 登録日 | 2023-07-07 | 公開日 | 2024-01-10 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural mechanism of TRPV5 inhibition by econazole. Structure, 32, 2024
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8TVP
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![BU of 8tvp by Molmil](/molmil-images/mine/8tvp) | Cryo-EM structure of CPD-stalled Pol II in complex with Rad26 (open state) | 分子名称: | DNA (NTS), DNA (TS), DNA repair and recombination protein RAD26, ... | 著者 | Sarsam, R.D, Lahiri, I, Leschziner, A.E. | 登録日 | 2023-08-18 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Elf1 promotes Rad26's interaction with lesion-arrested Pol II for transcription-coupled repair. Proc.Natl.Acad.Sci.USA, 121, 2024
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