PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

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2L6B	NRC consensus ankyrin repeat protein solution structure 分子名称: NR1C 著者 Aksel, T, Majumdar, A, Barrick, D. 登録日 2010-11-17 公開日 2011-03-23 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The contribution of entropy, enthalpy, and hydrophobic desolvation to cooperativity in repeat-protein folding. Structure, 19, 2011
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (5 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL1	Full-length insulin receptor bound with site 1 binding deficient mutant insulin (A-V3E) 分子名称: Insulin A chain, Insulin B chain, Insulin receptor 著者 Bai, X.C, Choi, E. 登録日 2021-10-22 公開日 2022-03-30 最終更新日 2022-04-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7S5O	Crystal structure of Cytochrome c' beta from Nitrosomonas europaea ATCC 19718 分子名称: ACETATE ION, Cytochrome_P460 domain-containing protein, HEME C, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2021-09-11 公開日 2022-03-30 最終更新日 2022-04-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Characterization of Cytochrome c ' beta-Met from an Ammonia-Oxidizing Bacterium. Biochemistry, 61, 2022
5HAL	Crystal Structure of a putative beta-lactamase from Burkholderia vietnamiensis 分子名称: 1,2-ETHANEDIOL, Uncharacterized protein 著者 Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2015-12-30 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1507 Å) 主引用文献 Crystal Structure of a putative beta-lactamase from Burkholderia vietnamiensis to be published
6DVL	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-115 分子名称: Hdac6 protein, N-[2-(cyclohexylamino)-2-oxoethyl]-N-{[4-(hydroxycarbamoyl)phenyl]methyl}-3,5-dimethylbenzamide, POTASSIUM ION, ... 著者 Porter, N.J, Christianson, D.W. 登録日 2018-06-24 公開日 2018-08-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity. J. Med. Chem., 61, 2018
6DVN	Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with DDK-137 分子名称: 1,2-ETHANEDIOL, Hdac6 protein, N-[2-(benzylamino)-2-oxoethyl]-4-(dimethylamino)-N-{[4-(hydroxycarbamoyl)phenyl]methyl}benzamide, ... 著者 Osko, J.D, Christianson, D.W. 登録日 2018-06-24 公開日 2018-08-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity. J. Med. Chem., 61, 2018
6DJC	Crystal structure of human Bromodomain-containing protein 4 (BRD4) bromodomain with MS645 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N,N'-(decane-1,10-diyl)bis{2-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetamide} 著者 Ren, C, Zhou, M.M. 登録日 2018-05-25 公開日 2018-07-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.46 Å) 主引用文献 Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5H6H	Crystal Structure of Hyperthermophilic Thermotoga maritima L-Ribulose 3-Epimerase with Mn2+ 分子名称: MANGANESE (II) ION, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL, ... 著者 Cao, T.-P, Choi, J.M, Shin, S.M, Le, D.W, Lee, S.H. 登録日 2016-11-13 公開日 2017-03-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.446 Å) 主引用文献 TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C5and C6Epimerization Reactions Appl. Environ. Microbiol., 83, 2017
2LT1	Solution NMR structure of the 72-residue N-terminal domain of Myxococcus xanthus CarD 分子名称: CarD protein 著者 Jimenez, M.A, Padmanabhan, S. 登録日 2012-05-10 公開日 2013-11-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structure-Function Dissection of Myxococcus xanthus CarD N-Terminal Domain, a Defining Member of the CarD_CdnL_TRCF Family of RNA Polymerase Interacting Proteins. Plos One, 10
5HAS	Crystal structure of the N-terminal DCB-HUS domain of T. terrestris Sec7 分子名称: Sec7 著者 Richardson, B.C, Fromme, J.C. 登録日 2015-12-30 公開日 2016-01-27 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.653 Å) 主引用文献 The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase. Elife, 5, 2016
4BPH	High resolution crystal structure of Bacillus subtilis DltC 分子名称: 4'-PHOSPHOPANTETHEINE, D-ALANINE--POLY(PHOSPHORIBITOL) LIGASE SUBUNIT 2, MAGNESIUM ION 著者 Zimmermann, S, Neumann, P, Stubbs, M.T. 登録日 2013-05-26 公開日 2014-06-11 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 High-Resolution Structures of the D-Alanyl Carrier Protein (Dcp) Dltc from Bacillus Subtilis Reveal Equivalent Conformations of Apo- and Holo-Forms FEBS Lett., 589, 2015
4C61	Inhibitors of Jak2 Kinase domain 分子名称: ACETATE ION, N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-7-methyl-N4-(1-methylimidazol-4-yl)thieno[3,2-d]pyrimidine-2,4-diamine, TYROSINE-PROTEIN KINASE JAK2 著者 Read, J.A, Green, I, Pollard, H, Howard, T. 登録日 2013-09-17 公開日 2014-01-08 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Discovery of 1-Methyl-1H-Imidazole Derivatives as Potent Jak2 Inhibitors. J.Med.Chem., 57, 2014
7PNE	Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop 分子名称: TTAMycdup-3sbl 著者 Vianney, Y.M, Weisz, K. 登録日 2021-09-06 公開日 2021-12-29 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces. Chemistry, 28, 2022
7PNG	Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid 分子名称: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine 著者 Vianney, Y.M, Weisz, K. 登録日 2021-09-06 公開日 2021-12-29 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces. Chemistry, 28, 2022
2MCW	Solid-state NMR structure of piscidin 3 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers 分子名称: Piscidin-3 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2014-03-19 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
5HT8	Crystal structure of clostrillin double mutant (S17H,S19H) in complex with nickel 分子名称: Beta and gamma crystallin, NICKEL (II) ION 著者 Jamkhindikar, A, Srivastava, S.S, Sankaranarayanan, R. 登録日 2016-01-26 公開日 2017-02-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 A Transition Metal-Binding, Trimeric beta gamma-Crystallin from Methane-Producing Thermophilic Archaea, Methanosaeta thermophila Biochemistry, 56, 2017
4DH3	Low temperature X-ray structure of cAMP dependent Protein Kinase A catalytic subunit with high Mg2+, ATP and IP20 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Kovalevsky, A.Y, Langan, P. 登録日 2012-01-27 公開日 2012-06-27 最終更新日 2013-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Low- and room-temperature X-ray structures of protein kinase A ternary complexes shed new light on its activity. Acta Crystallogr.,Sect.D, 68, 2012
4DIK	Flavo Di-iron protein H90A mutant from Thermotoga maritima 分子名称: CHLORIDE ION, FLAVOPROTEIN, MU-OXO-DIIRON 著者 Fang, H, Caranto, J.D, Taylor, A.B, Hart, P.J, Kurtz Jr, D.M. 登録日 2012-01-31 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Histidine ligand variants of a flavo-diiron protein: effects on structure and activities. J.Biol.Inorg.Chem., 17, 2012
4DN4	Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a 分子名称: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ... 著者 Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. 登録日 2012-02-08 公開日 2012-10-03 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
5XTJ	Mannanase(RmMan134A) 分子名称: Endo beta-1,4-mannanase 著者 Jiang, Z.Q, You, X, Huang, P. 登録日 2017-06-19 公開日 2018-06-27 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Structural and biochemical insights into the substrate-binding mechanism of a novel glycoside hydrolase family 134 beta-mannanase. Biochim Biophys Acta Gen Subj, 1862, 2018
6EEL	Crystal Structure of Myoferlin C2A with divalent cation 分子名称: Myoferlin, STRONTIUM ION 著者 Sutton, R.B, Harsini, F.M, Rice, A.M. 登録日 2018-08-14 公開日 2019-05-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structural Basis for the Distinct Membrane Binding Activity of the Homologous C2A Domains of Myoferlin and Dysferlin. J.Mol.Biol., 431, 2019
2MCV	Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers 分子名称: Moronecidin 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Hayden, R.M, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2014-03-19 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
1X09	Crystal structure of the D26A mutant UPPs in complex with magnesium and isopentenyl pyrophosphate 分子名称: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, MAGNESIUM ION, Undecaprenyl pyrophosphate synthetase 著者 Guo, R.-T, Ko, T.-P, Chen, A.P.-C, Kuo, C.-J, Wang, A.H.-J, Liang, P.-H. 登録日 2005-03-15 公開日 2005-03-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. J.Biol.Chem., 280, 2005

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