6UQ1
 
 | | RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 6 | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | | 著者 | Oh, J, Wang, D. | | 登録日 | 2019-10-18 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-pi and CH-pi interactions.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6O6C
 | | RNA polymerase II elongation complex arrested at a CPD lesion | | 分子名称: | DNA (27-MER), DNA (5'-D(P*GP*GP*AP*GP*AP*AP*GP*GP*AP*GP*CP*AP*GP*AP*GP*C)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Lahiri, I, Leshziner, A.E. | | 登録日 | 2019-03-05 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | 3.1 angstrom structure of yeast RNA polymerase II elongation complex stalled at a cyclobutane pyrimidine dimer lesion solved using streptavidin affinity grids.
J.Struct.Biol., 207, 2019
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1Y1Y
 | | RNA Polymerase II-TFIIS-DNA/RNA complex | | 分子名称: | 5'-D(P*TP*AP*CP*GP*CP*CP*T)-3', 5'-R(P*AP*GP*GP*C)-3', DNA-directed RNA polymerase II 13.6 kDa polypeptide, ... | | 著者 | Cramer, P, Kettenberger, H, Armache, K.-J. | | 登録日 | 2004-11-19 | | 公開日 | 2004-12-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS.
Mol.Cell, 16, 2004
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7OZN
 | | RNA Polymerase II dimer (Class 1) | | 分子名称: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Aibara, S, Dienemann, C, Cramer, P. | | 登録日 | 2021-06-28 | | 公開日 | 2021-10-06 | | 最終更新日 | 2021-10-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure of an inactive RNA polymerase II dimer.
Nucleic Acids Res., 49, 2021
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3M3Y
 | | RNA polymerase II elongation complex C | | 分子名称: | DNA (28-MER), DNA (5'-D(*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | | 登録日 | 2010-03-10 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3M4O
 | | RNA polymerase II elongation complex B | | 分子名称: | DNA (28-MER), DNA (5'-D(P*GP*TP*GP*GP*TP*TP*AP*TP*GP*GP*GP*TP*AP*G)-3'), DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Wang, D, Zhu, G, Huang, X, Lippard, S.J. | | 登録日 | 2010-03-11 | | 公開日 | 2010-05-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.57 Å) | | 主引用文献 | X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4A3I
 | | RNA Polymerase II binary complex with DNA | | 分子名称: | 5'-D(*GP*GP*CP*AP*CP*AP*AP*CP*TP*GP*CP*GP*GP*CP*T)-3', DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A93
 | | RNA Polymerase II elongation complex containing a CPD Lesion | | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*T*TTP*TP*TP*CP*C BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP*GP*CP*TP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*CP*AP*GP*GP*AP*AP)-3', ... | | 著者 | Walmacq, C, Cheung, A.C.M, Kireeva, M.L, Lubkowska, L, Ye, C, Gotte, D, Strathern, J.N, Carell, T, Cramer, P, Kashlev, M. | | 登録日 | 2011-11-23 | | 公開日 | 2012-03-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Mechanism of Translesion Transcription by RNA Polymerase II and its Role in Cellular Resistance to DNA Damage.
Mol.Cell, 46, 2012
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3H0G
 | | RNA Polymerase II from Schizosaccharomyces pombe | | 分子名称: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | | 登録日 | 2009-04-09 | | 公開日 | 2009-08-25 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4A3E
 | | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP | | 分子名称: | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3M
 | | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid and soaked with AMPCPP | | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP* TP*TP*CP*CP*BRUP*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*GP*GP*A)-3', ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3C
 | | RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid | | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-11-16 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3B
 | | RNA Polymerase II initial transcribing complex with a 4nt DNA-RNA hybrid | | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3J
 | | RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid and soaked with GMPCPP | | 分子名称: | 5'-D(*AP*GP*CP*TP*AP*GP*CP*TP*TP*TP*CP*BRUP*AP*CP*CP *TP*GP*AP*AP*CP*AP*AP*CP*TP*AP*AP*CP)-3', 5'-D(*GP*TP*AP*GP*AP*AP*AP*GP*CP*TP*AP*GP*CP*TP)-3', 5'-R(*CP*AP)-3', ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
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4A3L
 | | RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP | | 分子名称: | 5'-D(*AP*AP*GP*TP*AP*CP*TP)-3', 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*TP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3D
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid | | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3G
 | | RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid | | 分子名称: | DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2012-02-08 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3F
 | | RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP | | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*C BRU*GP*GP*TP*CP*AP*TP*T)-3', DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1, ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of initial RNA polymerase II transcription.
EMBO J., 30, 2011
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4A3K
 | | RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid | | 分子名称: | 5'-D(*AP*GP*CP*TP*CP*AP*AP*GP*TP*AP*CP*TP*TP*DTP *TP*TP*CP*CP*BRU*GP*GP*TP*CP*AP*TP*T)-3', 5'-D(*TP*AP*AP*GP*TP*AP*CP*TP*TP*GP*AP)-3', 5'-R(*AP*CP*CP*AP*GP*GP*AP)-3', ... | | 著者 | Cheung, A.C.M, Sainsbury, S, Cramer, P. | | 登録日 | 2011-09-30 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural Basis of Initial RNA Polymerase II Transcription.
Embo J., 30, 2011
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6HLR
 | | Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | | 登録日 | 2018-09-11 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
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6H68
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) with fully-ordered A49 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | 登録日 | 2018-07-26 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5W65
 | | RNA polymerase I Initial Transcribing Complex State 2 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Han, Y, He, Y. | | 登録日 | 2017-06-16 | | 公開日 | 2017-08-02 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
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5W64
 | | RNA Polymerase I Initial Transcribing Complex State 1 | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Han, Y, He, Y. | | 登録日 | 2017-06-16 | | 公開日 | 2017-07-26 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural mechanism of ATP-independent transcription initiation by RNA polymerase I.
Elife, 6, 2017
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6HLQ
 | | Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | | 登録日 | 2018-09-11 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.
Elife, 8, 2019
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6H67
 | | Yeast RNA polymerase I elongation complex stalled by cyclobutane pyrimidine dimer (CPD) | | 分子名称: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | | 著者 | Sanz-Murillo, M, Xu, J, Gil-Carton, D, Wang, D, Fernandez-Tornero, C. | | 登録日 | 2018-07-26 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of RNA polymerase I stalling at UV light-induced DNA damage.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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