PDB: 325 件ウェブページステータス検索Chemie searchBIRD

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7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-07-06 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
6PSQ	Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PST	Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
6PSV	Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter 分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2019-07-13 公開日 2020-03-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Stepwise Promoter Melting by Bacterial RNA Polymerase. Mol.Cell, 78, 2020
7BEG	Structures of class I bacterial transcription complexes 分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... 著者 Ye, F.Z, Hao, M, Zhang, X.D. 登録日 2020-12-23 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
7BEF	Structures of class II bacterial transcription complexes 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Hao, M, Ye, F.Z, Zhang, X.D. 登録日 2020-12-23 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.808 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer 分子名称: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1	Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP 分子名称: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7DY6	A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W. 登録日 2021-01-20 公開日 2021-11-17 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation. Biochem.Biophys.Res.Commun., 583, 2021
7C17	The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2020-05-02 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
4LK1	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.8369 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4JKR	Crystal Structure of E. coli RNA Polymerase in complex with ppGpp 分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA', DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, Wang, Y, Steitz, T.A. 登録日 2013-03-11 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 The mechanism of E. coli RNA polymerase regulation by ppGpp is suggested by the structure of their complex. Mol.Cell, 50, 2013
4LLG	Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-09 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.7936 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4JK1	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with Guanosine tetraphosphate (ppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4JK2	X-ray crystal structure of Escherichia coli sigma70 holoenzyme in complex with guanosine pentaphosphate (pppGpp) 分子名称: Escherichia coli RNA polymerase alpha subunit, Escherichia coli RNA polymerase beta subunit, Escherichia coli RNA polymerase beta' subunit, ... 著者 Murakami, K.S. 登録日 2013-03-09 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (4.201 Å) 主引用文献 Differential regulation by ppGpp versus pppGpp in Escherichia coli. Nucleic Acids Res., 41, 2013
4LJZ	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5871 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4KN4	X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2b 分子名称: Benzoxazinorifamycin-2b, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S. 登録日 2013-05-08 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.965 Å) 主引用文献 X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins. J.Med.Chem., 56, 2013
4KN7	X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2c 分子名称: Benzoxazinorifamycin-2c, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Murakami, K.S. 登録日 2013-05-08 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.686 Å) 主引用文献 X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins. J.Med.Chem., 56, 2013
4LK0	Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9103 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4KMU	X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S. 登録日 2013-05-08 公開日 2013-05-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins. J.Med.Chem., 56, 2013
4MEX	Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2014-06-25 実験手法 X-RAY DIFFRACTION (3.902 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
8TOE	Escherichia coli RNA polymerase unwinding intermediate (I1c) at the lambda PR promoter 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Saecker, R.M, Mueller, A.U. 登録日 2023-08-03 公開日 2024-07-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
8TO6	Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter 分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Saecker, R.M, Mueller, A.U. 登録日 2023-08-02 公開日 2024-07-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024
8TOM	Escherichia coli RNA polymerase closed complex intermediate at the lambda PR promoter 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Saecker, R.M, Mueller, A.U. 登録日 2023-08-03 公開日 2024-07-03 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024

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