PDB: 141 件ウェブページステータス検索Chemie searchBIRD

---

7PUX	Structure of p97 N-D1(L198W) in complex with Fragment TROLL2 分子名称: (1S)-2-amino-1-(4-bromophenyl)ethan-1-ol, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... 著者 Bothe, S, Schindelin, H. 登録日 2021-10-01 公開日 2022-12-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 Commun Chem, 5, 2022
7R7S	p47-bound p97-R155H mutant with ATPgammaS 分子名称: NSFL1 cofactor p47, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
7R7T	p47-bound p97-R155H mutant with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, NSFL1 cofactor p47, Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Malyutin, A.G, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
7R7U	D1 and D2 domain structure of the p97(R155H)-p47 complex 分子名称: Transitional endoplasmic reticulum ATPase 著者 Nandi, P, Li, S, Coulmbres, R.C.A, Wang, F, Williams, D.R, Poh, Y.-P, Chou, T.-F, Chiu, P.-L. 登録日 2021-06-25 公開日 2021-08-04 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural and Functional Analysis of Disease-Linked p97 ATPase Mutant Complexes. Int J Mol Sci, 22, 2021
7RLC	Cryo-EM structure of human p97-A232E mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RL7	Cryo-EM structure of human p97-R155H mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLJ	Cryo-EM structure of human p97 bound to CB-5083 and ATPgS. 分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RL9	Cryo-EM structure of human p97-R191Q mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RL6	Cryo-EM structure of human p97-R155H mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLF	Cryo-EM structure of human p97-E470D mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLI	Cryo-EM structure of human p97 bound to CB-5083 and ADP. 分子名称: 1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide, ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLA	Cryo-EM structure of human p97-R191Q mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLH	Cryo-EM structure of human p97-D592N mutant bound to ATPgS. 分子名称: MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLG	Cryo-EM structure of human p97-D592N mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLD	Cryo-EM structure of human p97-E470D mutant bound to ADP. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021
7RLB	Cryo-EM structure of human p97-A232E mutant bound to ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase 著者 Caffrey, B, Zhu, X, Berezuk, A, Tuttle, K, Chittori, S, Subramaniam, S. 登録日 2021-07-23 公開日 2021-09-22 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 AAA+ ATPase p97/VCP mutants and inhibitor binding disrupt inter-domain coupling and subsequent allosteric activation. J.Biol.Chem., 297, 2021

<123456