PDB: 811 件ウェブページステータス検索Chemie searchBIRD

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3EKE	Crystal structure of IBV X-domain at pH 5.6 分子名称: L(+)-TARTARIC ACID, Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-19 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
3GPO	Crystal structure of macro domain of Chikungunya virus in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Malet, H, Jamal, S, Coutard, B, Canard, B. 登録日 2009-03-23 公開日 2009-07-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
3GPG	Crystal structure of macro domain of Chikungunya virus 分子名称: Non-structural protein 3 著者 Malet, H, Jamal, S, Coutard, B, Canard, B. 登録日 2009-03-23 公開日 2009-07-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
3GQE	Crystal structure of macro domain of Venezuelan Equine Encephalitis virus 分子名称: BICINE, Non-structural protein 3 著者 Jamal, S, Malet, H, Coutard, B, Canard, B. 登録日 2009-03-24 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
3GQO	Crystal structure of macro domain of Venezuelan Equine Encephalitis virus in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Malet, H, Jamal, S, Coutard, B, Ferron, F, Canard, B. 登録日 2009-03-24 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
3GPQ	Crystal structure of macro domain of Chikungunya virus in complex with RNA 分子名称: Non-structural protein 3, RNA (5'-R(*AP*AP*A)-3') 著者 Malet, H, Jamal, S, Coutard, B, Canard, B. 登録日 2009-03-23 公開日 2009-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structures of Chikungunya and Venezuelan equine encephalitis virus nsP3 macro domains define a conserved adenosine binding pocket J.Virol., 83, 2009
3EJF	Crystal structure of IBV X-domain at pH 8.5 分子名称: Non-structural protein 3 著者 Piotrowski, Y, Hansen, G, Hilgenfeld, R. 登録日 2008-09-18 公開日 2008-09-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property. Protein Sci., 18, 2009
6W0T	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 6-(2-methylpropyl)-2-oxidanylidene-5~{H}-pyrimidine-4-carboxylic acid, Non-structural protein 3 著者 Wu, M, Zhang, S. 登録日 2020-03-02 公開日 2021-01-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W7H	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 6-methyl-2-oxo-2,5-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Augelli-Szafran, C.E, Pathak, A.K, Wu, M. 登録日 2020-03-19 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8K	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 5,6-dimethyl-2-oxo-2,3-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Augelli-Szafran, C.E, Pathak, A.K, Wu, M. 登録日 2020-03-20 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8M	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-1,2-dihydroquinazoline-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-20 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8Q	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-1,2,5,6,7,8-hexahydroquinazoline-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6VXS	Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 分子名称: 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Non-structural protein 3, ... 著者 Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-02-24 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
6VUQ	Crystal structure of CHIKV nsP3 macrodomain soaked with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Nonstructural polyprotein 著者 Wu, M. 登録日 2020-02-16 公開日 2021-01-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W02	Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 in the complex with ADP ribose 分子名称: 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-02-28 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
6W8Y	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: 2-oxo-2,3-dihydropyrimidine-4-carboxylic acid, Nonstructural polyprotein 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W8Z	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: Nonstructural polyprotein, methyl 2-oxo-1,2-dihydroquinazoline-4-carboxylate 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W91	Co-crystal structures of CHIKV nsP3 macrodomain with pyrimidone fragments 分子名称: Nonstructural polyprotein, methyl 2-oxo-2,5-dihydropyrimidine-4-carboxylate 著者 Zhang, S, Garzan, A, Pathak, A.K, Augelli-Szafran, C.E, Wu, M. 登録日 2020-03-21 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design. Plos One, 16, 2021
6W6Y	Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 in complex with AMP 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE MONOPHOSPHATE, Non-structural protein 3 著者 Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-03-18 公開日 2020-03-25 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
6WCF	Crystal Structure of ADP ribose phosphatase of NSP3 from SARS-CoV-2 in complex with MES 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural protein 3 著者 Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-03-30 公開日 2020-04-15 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.065 Å) 主引用文献 Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
6WOJ	Structure of the SARS-CoV-2 macrodomain (NSP3) in complex with ADP-ribose 分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 著者 Lovell, S, Kashipathy, M.M, Battaile, K.P, Gao, F.P, Fehr, A.R. 登録日 2020-04-24 公開日 2020-05-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. J.Virol., 95, 2021
6WEY	High-resolution structure of the SARS-CoV-2 NSP3 Macro X domain 分子名称: Non-structural protein 3 著者 Vuksanovic, N, Silvaggi, N.R. 登録日 2020-04-03 公開日 2020-04-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.95 Å) 主引用文献 Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3. Biochemistry, 59, 2020
7TWT	Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at pH 4 (P43 crystal form) 分子名称: Non-structural protein 3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Correy, G.J, Fraser, J.S. 登録日 2022-02-07 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at pH 4 (P43 crystal form) To Be Published
7TWR	Crystal structure of SARS-CoV-2 NSP3 macrodomain at pH 8 (P43 crystal form) 分子名称: ACETATE ION, Non-structural protein 3 著者 Correy, G.J, Fraser, J.S. 登録日 2022-02-07 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature. Sci Adv, 8, 2022
7TX1	Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at pH 10 (P43 crystal form) 分子名称: Non-structural protein 3, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE 著者 Correy, G.J, Fraser, J.S. 登録日 2022-02-07 公開日 2022-02-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (0.9 Å) 主引用文献 Crystal structure of SARS-CoV-2 NSP3 macrodomain in complex with ADP-ribose at pH 10 (P43 crystal form) To Be Published

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