PDB: 195 件ウェブページステータス検索Chemie searchBIRD

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6EHT	Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme 分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ... 著者 De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A. 登録日 2017-09-15 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 p15PAF binding to PCNA modulates the DNA sliding surface. Nucleic Acids Res., 46, 2018
6E49	Pif1 peptide bound to PCNA trimer 分子名称: ATP-dependent DNA helicase PIF1, Proliferating cell nuclear antigen 著者 Buzovetsky, O, Kwon, Y, Pham, N.T, Kim, C, Ira, G, Sung, P, Xiong, Y. 登録日 2018-07-17 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Role of the Pif1-PCNA Complex in Pol delta-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication. Cell Rep, 21, 2017
6FCM	Crystal structure of human PCNA 分子名称: Proliferating cell nuclear antigen 著者 Housset, D, Frachet, P. 登録日 2017-12-20 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils. J.Exp.Med., 216, 2019
8E84	Human PCNA mutant- C148S 分子名称: Proliferating cell nuclear antigen 著者 Magrino, J, Page, B, Gaubitz, C, Kelch, B.A. 登録日 2022-08-25 公開日 2023-04-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A thermosensitive PCNA allele underlies an ataxia-telangiectasia-like disorder. J.Biol.Chem., 299, 2023
7M5M	PCNA bound to peptide mimetic 分子名称: N-BUTANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2021-03-24 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
7M5L	PCNA bound to peptide mimetic with linker 分子名称: PROPANE, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2021-03-24 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
7M5N	PCNA bound to peptide mimetic with linker 分子名称: 1,3-dimethylbenzene, Peptide mimetic (ACE)RQCSMTCFYHSK(NH2) with linker, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2021-03-24 公開日 2021-08-11 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 A cell permeable bimane-constrained PCNA-interacting peptide. Rsc Chem Biol, 2, 2021
7KQ1	PCNA bound to truncated peptide mimetic 分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2020-11-13 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
7KQ0	PCNA bound to peptide mimetic 分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen 著者 Vandborg, B.A, Bruning, J.B. 登録日 2020-11-13 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA. J.Biol.Chem., 296, 2021
7N5K	PCNA from Thermococcus gammatolerans: crystal II, collection 1, 1.98 A, 3.84 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
7N5J	PCNA from Thermococcus gammatolerans: crystal I, collection 5, 2.82 A, 89.1 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
7N5M	PCNA from Thermococcus gammatolerans: crystal III, collection 1, 2.00 A, 1.91 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
7N5I	PCNA from Thermococcus gammatolerans: crystal I, collection 1, 1.95 A, 5.22 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
7N5N	PCNA from Thermococcus gammatolerans: crystal III, collection 15, 2.20 A, 28.7 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
7N5L	PCNA from Thermococcus gammatolerans: crystal II, collection 20, 3.07 A, 77.0 MGy 分子名称: DNA polymerase sliding clamp, GLYCEROL, SULFATE ION 著者 Marin-Tovar, Y, Rudino-Pinera, E. 登録日 2021-06-05 公開日 2022-05-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3.07 Å) 主引用文献 PCNA from Thermococcus gammatolerans: A protein involved in chromosomal DNA metabolism intrinsically resistant at high levels of ionizing radiation. Proteins, 90, 2022
5JNE	E2-SUMO-Siz1 E3-SUMO-PCNA complex 分子名称: E3 SUMO-protein ligase SIZ1,Ubiquitin-like protein SMT3, GLYCEROL, Proliferating cell nuclear antigen, ... 著者 Lima, C.D, Streich Jr, F.C. 登録日 2016-04-29 公開日 2016-08-10 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Capturing a substrate in an activated RING E3/E2-SUMO complex. Nature, 536, 2016
6VVO	Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen, PCNA) 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 Gaubitz, C, Liu, X, Stone, N.P, Kelch, B.A. 登録日 2020-02-18 公開日 2020-02-26 最終更新日 2020-03-25 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of the human clamp loader bound to the sliding clamp: a further twist on AAA+ mechanism Biorxiv, 2020
7KC0	Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp 分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... 著者 Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. 登録日 2020-10-04 公開日 2020-12-02 最終更新日 2020-12-16 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
8PPU	Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing three consecutive mismatches 分子名称: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(C7R)P*(PST)P*(PST)P*(PST))-3'), DNA polymerase II small subunit, ... 著者 Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. 登録日 2023-07-10 公開日 2023-12-20 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
8PPV	Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template substrate containing three consecutive mismatches 分子名称: DNA (5'-D(*P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*(GS)P*(G7P)P*(PST)P*(PST)P*(PST))-3'), DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA polymerase II small subunit, ... 著者 Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. 登録日 2023-07-10 公開日 2023-12-20 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
8PPT	Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate containing a mismatch 分子名称: DNA (5'-D(P*AP*GP*CP*AP*CP*GP*GP*CP*TP*CP*GP*GP*CP*CP*CP*GP*G)-3'), DNA (5'-D(P*CP*CP*GP*GP*GP*CP*CP*GP*AP*GP*CP*CP*GP*TP*GP*CP*TP*TP*T)-3'), DNA polymerase II small subunit, ... 著者 Betancurt-Anzola, L, Martinez-Carranza, M, Zatopek, K.M, Gardner, A.F, Sauguet, L. 登録日 2023-07-10 公開日 2023-12-20 最終更新日 2023-12-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular basis for proofreading by the unique exonuclease domain of Family-D DNA polymerases. Nat Commun, 14, 2023
3PGE	Structure of sumoylated PCNA 分子名称: Proliferating cell nuclear antigen, SUMO-modified proliferating cell nuclear antigen 著者 Freudenthal, B.D, Brogie, J.E, Gakhar, L, Washington, T. 登録日 2010-11-01 公開日 2010-12-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of SUMO-Modified Proliferating Cell Nuclear Antigen. J.Mol.Biol., 406, 2011
6TNY	Processive human polymerase delta holoenzyme 分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... 著者 Lancey, C, Hamdan, S.M, De Biasio, A. 登録日 2019-12-10 公開日 2019-12-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
6TNZ	Human polymerase delta-FEN1-PCNA toolbelt 分子名称: DNA polymerase delta catalytic subunit, DNA polymerase delta subunit 2, DNA polymerase delta subunit 3, ... 著者 Lancey, C, Hamdan, S.M, De Biasio, A. 登録日 2019-12-10 公開日 2019-12-18 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 Structure of the processive human Pol delta holoenzyme. Nat Commun, 11, 2020
6T8H	Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi 分子名称: DNA polymerase II small subunit, DNA polymerase sliding clamp, DNA primer, ... 著者 Madru, C, Raia, P, Hugonneau Beaufet, I, Pehau-Arnaudet, G, England, P, Lindhal, E, Delarue, M, Carroni, M, Sauguet, L. 登録日 2019-10-24 公開日 2020-03-04 最終更新日 2020-04-08 実験手法 ELECTRON MICROSCOPY (3.77 Å) 主引用文献 Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA. Nat Commun, 11, 2020

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