7VBP
 
 | | Membrane arm of deactive state CI from DQ-NADH dataset | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-09-01 | | 公開日 | 2022-04-06 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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8BQ6
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 2 composition) | | 分子名称: | 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-11-18 | | 公開日 | 2023-05-10 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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8BQ5
 | | Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (Complete conformation 1 composition) | | 分子名称: | 2,3-DIMETHOXY-5-METHYL-6-(3,11,15,19-TETRAMETHYL-EICOSA-2,6,10,14,18-PENTAENYL)-[1,4]BENZOQUINONE, AT3G07480.1, Acyl carrier protein 1, ... | | 著者 | Klusch, N, Kuehlbrandt, W. | | 登録日 | 2022-11-18 | | 公開日 | 2023-03-22 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Cryo-EM structure of the respiratory I + III 2 supercomplex from Arabidopsis thaliana at 2 angstrom resolution.
Nat.Plants, 9, 2023
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7V3M
 | | Deactive state complex I from rotenone-NADH dataset | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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7V32
 | | Deactive state complex I from rotenone dataset | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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7V2C
 | | Active state complex I from Q10 dataset | | 分子名称: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-08 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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7V31
 | | Active state complex I from rotenone dataset | | 分子名称: | (2R,6aS,12aS)-8,9-dimethoxy-2-(prop-1-en-2-yl)-1,2,12,12a-tetrahydrofuro[2',3':7,8][1]benzopyrano[2,3-c][1]benzopyran-6(6aH)-one, (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | | 著者 | Gu, J.K, Yang, M.J. | | 登録日 | 2021-08-10 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | The coupling mechanism of mammalian mitochondrial complex I.
Nat.Struct.Mol.Biol., 29, 2022
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7QSD
 | | Bovine complex I in the active state at 3.1 A | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7QSL
 | | Bovine complex I in lipid nanodisc, Active-apo | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSM
 | | Bovine complex I in lipid nanodisc, Deactive-ligand (composite) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSN
 | | Bovine complex I in lipid nanodisc, Deactive-apo | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSK
 | | Bovine complex I in lipid nanodisc, Active-Q10 | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7QSO
 | | Bovine complex I in lipid nanodisc, State 3 (Slack) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Chung, I, Bridges, H.R, Hirst, J. | | 登録日 | 2022-01-13 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-09-28 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.
Nat Commun, 13, 2022
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7R4D
 | | Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R4G
 | | Bovine complex I in the presence of IM1761092, slack class ii (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R41
 | | Bovine complex I in the presence of IM1761092, active class i (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R42
 | | Bovine complex I in the presence of IM1761092, active class ii (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R44
 | | Bovine complex I in the presence of IM1761092, active class iv (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R45
 | | Bovine complex I in the presence of IM1761092, deactive class i (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R46
 | | Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R43
 | | Bovine complex I in the presence of IM1761092, active class iii (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R48
 | | Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R47
 | | Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R4C
 | | Bovine complex I in the presence of IM1761092, deactive class v (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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7R4F
 | | Bovine complex I in the presence of IM1761092, slack class i (Composite map) | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | | 登録日 | 2022-02-08 | | 公開日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.
Science, 379, 2023
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