PDB: 221 件ウェブページステータス検索Chemie searchBIRD

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2N8S	Solution Structure of the rNedd4 WW1 Domain by NMR 分子名称: E3 ubiquitin-protein ligase NEDD4 著者 Spagnol, G, Kieken, F, Sorgen, P.L. 登録日 2015-10-27 公開日 2016-02-24 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus. J. Biol. Chem., 291, 2016
2N8T	Solution Structure of the rNedd4 WW2 Domain-Cx43CT Peptide Complex by NMR 分子名称: Cx43CT Peptide, E3 ubiquitin-protein ligase NEDD4 著者 Spagnol, G, Kieken, F, Sorgen, P.L. 登録日 2015-10-27 公開日 2016-02-24 最終更新日 2017-03-22 実験手法 SOLUTION NMR 主引用文献 Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus. J. Biol. Chem., 291, 2016
2N1O	PIN1 WW domain in complex with a phosphorylated CPEB1 derived peptide 分子名称: Cytoplasmic polyadenylation element-binding protein 1, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Schelhorn, C, Macias, M, Martin-Malpartida, P. 登録日 2015-04-13 公開日 2015-10-28 実験手法 SOLUTION NMR 主引用文献 Structural Analysis of the Pin1-CPEB1 interaction and its potential role in CPEB1 degradation. Sci Rep, 5, 2015
2MWB	FBP28 WW2 mutant W457F 分子名称: Transcription elongation regulator 1 著者 Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. 登録日 2014-11-03 公開日 2014-12-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
2MWD	NMR structure of FBP28 WW2 mutant Y438R DNDC 分子名称: Transcription elongation regulator 1 著者 Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. 登録日 2014-11-04 公開日 2014-12-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
2MDI	Solution structure of the PP2WW mutant (KPP2WW) of HYPB 分子名称: Histone-lysine N-methyltransferase SETD2 著者 Gao, Y.G, Hu, H.Y. 登録日 2013-09-10 公開日 2014-09-10 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Autoinhibitory structure of the WW domain of HYPB/SETD2 regulates its interaction with the proline-rich region of huntingtin. Structure, 22, 2014
2M8I	Structure of Pin1 WW domain 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Luh, L.M, Kirchner, D.K, Loehr, F, Haensel, R, Doetsch, V. 登録日 2013-05-22 公開日 2014-04-09 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition. J.Am.Chem.Soc., 135, 2013
2M9I	NMR solution structure of Pin1 WW domain variant 6-1 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Enck, S, Chen, W, Price, J.L, Powers, E.T, Wong, C, Dyson, H.J, Kelly, J.W. 登録日 2013-06-10 公開日 2013-06-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins. J.Am.Chem.Soc., 135, 2013
2M3O	Structure and dynamics of a human Nedd4 WW domain-ENaC complex 分子名称: Amiloride-sensitive sodium channel subunit alpha, E3 ubiquitin-protein ligase NEDD4 著者 Bobby, R, Medini, K, Neudecker, P, Lee, V, MacDonald, F.J, Brimble, M.A, Lott, J, Dingley, A.J. 登録日 2013-01-23 公開日 2013-08-28 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Structure and dynamics of human Nedd4-1 WW3 in complex with the alpha ENaC PY motif. Biochim.Biophys.Acta, 1834, 2013
1F8A	STRUCTURAL BASIS FOR THE PHOSPHOSERINE-PROLINE RECOGNITION BY GROUP IV WW DOMAINS 分子名称: PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 1, Y(SEP)PT(SEP)S PEPTIDE 著者 Verdecia, M.A, Bowman, M.E, Lu, K.P, Hunter, T, Noel, J.P. 登録日 2000-06-29 公開日 2000-08-23 最終更新日 2013-05-22 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structural basis for phosphoserine-proline recognition by group IV WW domains. Nat.Struct.Biol., 7, 2000
6VAJ	Crystal Structure Analysis of human PIN1 分子名称: 2-chloro-N-(2,2-dimethylpropyl)-N-[(3R)-1,1-dioxo-1lambda~6~-thiolan-3-yl]acetamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION, ... 著者 Seo, H.-S, Dhe-Paganon, S. 登録日 2019-12-17 公開日 2020-12-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo. Nat.Chem.Biol., 17, 2021
3WH0	Structure of Pin1 Complex with 18-crown-6 分子名称: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Lee, C.C, Liu, C.I, Jeng, W.Y, Wang, A.H.J. 登録日 2013-08-20 公開日 2014-10-15 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crowning proteins: modulating the protein surface properties using crown ethers. Angew.Chem.Int.Ed.Engl., 53, 2014
7KKF	Crystal Structure of S. cerevisiae Ess1 分子名称: Peptidyl-prolyl cis-trans isomerase ESS1 著者 Namitz, K.E.W, Alicea-Velazquez, N.L, Cosgrove, M.S, Hanes, S.D. 登録日 2020-10-27 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism. Commun Biol, 4, 2021
9EQH	WWP2 WW2-2,3-linker-HECT (WWP2-LH) 分子名称: GLYCEROL, Isoform 2 of NEDD4-like E3 ubiquitin-protein ligase WWP2, SODIUM ION 著者 Dudey, A.P, Hemmings, A.M. 登録日 2024-03-21 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Expanding the Inhibitor Space of the WWP1 and WWP2 HECT E3 Ligases To Be Published
9EQK	WWP1 WW2-2,3-linker-WW3-WW4-HECT (WWP1-2L34H) with ordered WW2 domain 分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP1 著者 Dudey, A.P, Hemmings, A.M. 登録日 2024-03-21 公開日 2024-05-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Expanding the Inhibitor Space of the WWP1 and WWP2 HECT E3 Ligases To Be Published
4QIB	Oxidation-Mediated Inhibition of the Peptidyl-Prolyl Isomerase Pin1 分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, SULFATE ION 著者 Innes, B.T, Sowole, M.A, Konermann, L, Litchfield, D.W, Brandl, C.J, Shilton, B.H. 登録日 2014-05-30 公開日 2015-02-04 最終更新日 2015-03-04 実験手法 X-RAY DIFFRACTION (1.865 Å) 主引用文献 Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1. Biochim.Biophys.Acta, 1852, 2015
5XMC	Crystal structure of the auto-inhibited Nedd4 family E3 ligase Itch 分子名称: E3 ubiquitin-protein ligase Itchy 著者 Shan, Z, Wen, W. 登録日 2017-05-13 公開日 2017-08-02 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch EMBO Rep., 18, 2017
7SA5	Two-state solution NMR structure of Apo Pin1 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Born, A, Vogeli, B. 登録日 2021-09-22 公開日 2021-10-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance. J.Am.Chem.Soc., 143, 2021
7SUQ	Two-state solution NMR structure of Pin1 bound to peptide FFpSPR 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Born, A, Vogeli, B. 登録日 2021-11-17 公開日 2022-08-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ligand-specific conformational change drives interdomain allostery in Pin1. Nat Commun, 13, 2022
7SUR	Two-state solution NMR structure of Pin1 bound to peptide pCDC25c 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Born, A, Vogeli, B. 登録日 2021-11-17 公開日 2022-08-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Ligand-specific conformational change drives interdomain allostery in Pin1. Nat Commun, 13, 2022
1PIN	PIN1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM HOMO SAPIENS 分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ALANINE, PEPTIDYL-PROLYL CIS-TRANS ISOMERASE, ... 著者 Noel, J.P, Ranganathan, R, Hunter, T. 登録日 1998-06-21 公開日 1998-10-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent. Cell(Cambridge,Mass.), 89, 1997
1NMV	Solution structure of human Pin1 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Bayer, E, Goettsch, S, Mueller, J.W, Griewel, B, Guiberman, E, Mayr, L, Bayer, P. 登録日 2003-01-11 公開日 2003-08-12 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structural Analysis of the Mitotic Regulator hPin1 in Solution: INSIGHTS INTO DOMAIN ARCHITECTURE AND SUBSTRATE BINDING. J.Biol.Chem., 278, 2003
5B3Y	Crystal structure of hPin1 WW domain (5-23) fused with maltose-binding protein 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Hanazono, Y, Takeda, K, Miki, K. 登録日 2016-03-17 公開日 2016-10-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein Sci Rep, 6, 2016
3TC5	Selective targeting of disease-relevant protein binding domains by O-phosphorylated natural product derivatives 分子名称: (11alpha,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl dihydrogen phosphate, HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Graeber, M, Janczyk, W, Sperl, B, Elumalai, N, Kozany, C, Hausch, F, Holak, T.A, Berg, T. 登録日 2011-08-08 公開日 2011-08-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Selective targeting of disease-relevant protein binding domains by o-phosphorylated natural product derivatives. Acs Chem.Biol., 6, 2011
5B3Z	Crystal structure of hPin1 WW domain (5-39) fused with maltose-binding protein 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1,Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Hanazono, Y, Takeda, K, Miki, K. 登録日 2016-03-17 公開日 2016-10-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural studies of the N-terminal fragments of the WW domain: Insights into co-translational folding of a beta-sheet protein Sci Rep, 6, 2016

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