PDB: 621 件ウェブページステータス検索Chemie searchBIRD

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6BCR	Complex of 14-3-3 theta with an IRSp53 peptide phosphorylated at T340 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, DI(HYDROXYETHYL)ETHER, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.986 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6BQT	Complex of 14-3-3 theta with an IRSp53 peptide doubly-phosphorylated at T340 and T360 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein theta, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, ... 著者 Kast, D.J, Dominguez, R. 登録日 2017-11-28 公開日 2018-12-05 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanism of IRSp53 inhibition by 14-3-3. Nat Commun, 10, 2019
6BYK	Structure of 14-3-3 beta/alpha bound to O-ClcNAc peptide 分子名称: 14-3-3 protein beta/alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ATPPVSQASSTT O-GlcNac peptide 著者 Schumacher, M.A. 登録日 2017-12-20 公開日 2018-05-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
6BZD	Structure of 14-3-3 gamma R57E mutant bound to GlcNAcylated peptide 分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, GlcNAcylated peptide 著者 Schumacher, M.A. 登録日 2017-12-22 公開日 2018-05-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BYJ	Structure of human 14-3-3 gamma bound to O-GlcNAc peptide 分子名称: 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSTTATPPVSQASSTTTSTW O-GlcNac peptide 著者 Schumacher, M.A. 登録日 2017-12-20 公開日 2018-05-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
6W0L	Henipavirus W protein interacts with 14-3-3 to modulate host gene expression 分子名称: 14-3-3 protein sigma, CALCIUM ION, Phosphorylated W peptide 著者 Edwards, M, Hoad, M, Tsimbalyuk, S, Menicucci, A, Messaoudi, I, Forwood, J, Basler, C. 登録日 2020-03-01 公開日 2020-04-22 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Henipavirus W Proteins Interact with 14-3-3 To Modulate Host Gene Expression. J.Virol., 94, 2020
3LW1	Binary complex of 14-3-3 sigma and p53 pT387-peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Schumacher, B, Mondry, J, Thiel, P, Weyand, M, Ottmann, C. 登録日 2010-02-23 公開日 2010-03-23 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Structure of the p53 C-terminus bound to 14-3-3: Implications for stabilization of the p53 tetramer Febs Lett., 584, 2010
3O8I	Structure of 14-3-3 isoform sigma in complex with a C-Raf1 peptide and a stabilizing small molecule fragment 分子名称: 14-3-3 binding site peptide of RAF proto-oncogene serine/threonine-protein kinase, 14-3-3 protein sigma, 6,6-dihydroxy-1-methoxyhexan-2-one 著者 Ottmann, C, Rose, R, Kaiser, M, Kuhenne, P. 登録日 2010-08-03 公開日 2010-09-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling Mol.Cell.Biol., 30, 2010
3P1S	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer fusicoccin A 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3NKX	Impaired binding of 14-3-3 to Raf1 is linked to Noonan and LEOPARD syndrome 分子名称: 14-3-3 protein zeta/delta, PROPANOIC ACID, Peptide of RAF proto-oncogene serine/threonine-protein kinase 著者 Schumacher, B, Weyand, M, Ottmann, C. 登録日 2010-06-21 公開日 2010-09-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling Mol.Cell.Biol., 30, 2010
3P1R	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3P1Q	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 Peptide and stabilizer fusicoccin A 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3P1P	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3M51	Structure of the 14-3-3/PMA2 complex stabilized by Pyrrolidone1 分子名称: 14-3-3-like protein C, 2-hydroxy-5-[(5S)-3-hydroxy-5-(4-nitrophenyl)-2-oxo-4-(phenylcarbonyl)-2,5-dihydro-1H-pyrrol-1-yl]benzoic acid, N.plumbaginifolia H+-translocating ATPase mRNA 著者 Ottmann, C, Rose, R, Waldmann, H. 登録日 2010-03-12 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions Angew.Chem.Int.Ed.Engl., 49, 2010
3M50	Structure of the 14-3-3/PMA2 complex stabilized by Epibestatin 分子名称: 14-3-3-like protein C, N-[(2R,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]-L-leucine, N.plumbaginifolia H+-translocating ATPase mRNA 著者 Ottmann, C, Rose, R, Waldmann, H. 登録日 2010-03-12 公開日 2010-05-26 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Identification and structure of small-molecule stabilizers of 14-3-3 protein-protein interactions Angew.Chem.Int.Ed.Engl., 49, 2010
3MHR	14-3-3 sigma in complex with YAP pS127-peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Schumacher, B, Skwarczynska, M, Rose, R, Ottmann, C. 登録日 2010-04-08 公開日 2010-09-15 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.15 Å) 主引用文献 Structure of a 14-3-3[sigma]-YAP phosphopeptide complex at 1.15 A resolution Acta Crystallogr.,Sect.F, 66, 2010
3P1O	Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilisator Fusicoccin A 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CALCIUM ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3P1N	Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide 分子名称: 14-3-3 protein sigma, 6-mer peptide from Potassium channel subfamily K member 9, CHLORIDE ION, ... 著者 Anders, C, Higuchi, Y, Schumacher, B, Thiel, P, Kato, N, Ottmann, C. 登録日 2010-09-30 公開日 2011-10-12 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface Chem. Biol., 20, 2013
3SML	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A aglycone, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SP5	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenol 分子名称: 14-3-3 protein sigma, Cotylenol, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-01 公開日 2016-05-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem.Biol., 20, 2013
3SPR	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer FC-THF 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin A-THF, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-07-03 公開日 2012-07-04 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3T0L	Small-molecule inhibitors of 14-3-3 protein-protein interactions from virtual screening 分子名称: 14-3-3 protein sigma, CHLORIDE ION, GLYCEROL, ... 著者 Thiel, P, Ottmann, C. 登録日 2011-07-20 公開日 2012-12-26 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Virtual screening and experimental validation reveal novel small-molecule inhibitors of 14-3-3 protein-protein interactions. Chem.Commun.(Camb.), 49, 2013
3SMO	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin J aglycone 分子名称: 14-3-3 protein sigma, Fusicoccin J aglycone, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SMM	Crystal structure of human 14-3-3 sigma C38N/N166H in complex with task-3 peptide and stabilizer Fusicoccin J aglycone 分子名称: 14-3-3 protein sigma, CHLORIDE ION, Fusicoccin J aglycone, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013
3SMK	Crystal structure of human 14-3-3 sigma C38V/N166H in complex with TASK-3 peptide and stabilizer Cotylenin A 分子名称: 14-3-3 protein sigma, Cotylenin A, MAGNESIUM ION, ... 著者 Anders, C, Schumacher, B, Ottmann, C. 登録日 2011-06-28 公開日 2012-07-11 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface. Chem. Biol., 20, 2013

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