PDB: 259 件ウェブページステータス検索Chemie searchBIRD

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8SXZ	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-24 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.26 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8SZ7	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the second PH domain 分子名称: Dynamin-1 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-27 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.84 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8SZ4	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state showing the PH domain 分子名称: Dynamin-1 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-05-26 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8T0R	Cryo-EM of the GDP-bound human dynamin (full-length) polymer assembled on the membrane in the super constricted state (full helix) 分子名称: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. 登録日 2023-06-01 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
4Y93	Crystal structure of the PH-TH-kinase construct of Bruton's tyrosine kinase (Btk) 分子名称: 4-tert-butyl-N-[2-methyl-3-(4-methyl-6-{[4-(morpholin-4-ylcarbonyl)phenyl]amino}-5-oxo-4,5-dihydropyrazin-2-yl)phenyl]benzamide, CALCIUM ION, Non-specific protein-tyrosine kinase,Non-specific protein-tyrosine kinase, ... 著者 Wang, Q, Kuriyan, J. 登録日 2015-02-16 公開日 2015-03-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.695 Å) 主引用文献 Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife, 4, 2015
5A3F	Crystal structure of the dynamin tetramer 分子名称: DYNAMIN 3 著者 Reubold, T.F, Faelber, K, Plattner, N, Posor, Y, Branz, K, Curth, U, Schlegel, J, Anand, R, Manstein, D.J, Noe, F, Haucke, V, Daumke, O, Eschenburg, S. 登録日 2015-05-29 公開日 2015-08-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal Structure of the Dynamin Tetramer Nature, 525, 2015
8S93	Crystal structure of the PH-TH/kinase complex of Bruton's tyrosine kinase 分子名称: 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, GLYCEROL, Tyrosine-protein kinase BTK, ... 著者 Lin, D.Y, Andreotti, A.H. 登録日 2023-03-27 公開日 2023-08-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife, 12, 2024
5C5B	Crystal Structure of Human APPL BAR-PH Heterodimer 分子名称: DCC-interacting protein 13-alpha, DCC-interacting protein 13-beta, GLYCEROL 著者 Chen, Y.J, Chen, B. 登録日 2015-06-19 公開日 2016-06-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of Human APPL BAR-PH Heterodimer To Be Published
4BBK	Structural and functional characterisation of the kindlin-1 pleckstrin homology domain 分子名称: FERMITIN FAMILY HOMOLOG 1, GLYCEROL 著者 Yates, L.A, Lumb, C.N, Brahme, N.N, Zalyte, R, Bird, L.E, De Colibus, L, Owens, R.J, Calderwood, D.A, Sansom, M.S.P, Gilbert, R.J.C. 登録日 2012-09-25 公開日 2012-11-14 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and Functional Characterisation of the Kindlin-1 Pleckstrin Homology Domain J.Biol.Chem., 287, 2012
6FSF	Crystal structure of the tandem PX-PH-domains of Bem3 from Saccharomyces cerevisiae 分子名称: GTPase-activating protein BEM3 著者 Ali, I, Eu, S, Koch, D, Bleimling, N, Goody, R.S, Mueller, M.P. 登録日 2018-02-19 公開日 2018-05-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta Crystallogr F Struct Biol Commun, 74, 2018
4CKH	Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy 分子名称: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 著者 Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. 登録日 2014-01-06 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
4CKG	Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy 分子名称: ARF-GAP WITH COILED-COIL, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 1 著者 Pang, X.Y, Fan, J, Zhang, Y, Zhang, K, Gao, B.Q, Ma, J, Li, J, Deng, Y.C, Zhou, Q.J, Hsu, V, Sun, F. 登録日 2014-01-06 公開日 2014-10-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (15 Å) 主引用文献 A Ph Domain in Acap1 Possesses Key Features of the Bar Domain in Promoting Membrane Curvature. Dev.Cell, 31, 2014
4F7H	The crystal structure of kindlin-2 pleckstrin homology domain in free form 分子名称: Fermitin family homolog 2, S,R MESO-TARTARIC ACID 著者 Liu, Y, Zhu, Y, Qin, J, Ye, S, Zhang, R. 登録日 2012-05-16 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of kindlin-2 PH domain reveals a conformational transition for its membrane anchoring and regulation of integrin activation. Protein Cell, 3, 2012
2LKO	Structural Basis of Phosphoinositide Binding to Kindlin-2 Pleckstrin Homology Domain in Regulating Integrin Activation 分子名称: Fermitin family homolog 2, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Liu, J, Fukuda, K, Xu, Z. 登録日 2011-10-17 公開日 2011-10-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural basis of phosphoinositide binding to kindlin-2 protein pleckstrin homology domain in regulating integrin activation. J.Biol.Chem., 286, 2011
2LUL	Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C 分子名称: Tyrosine-protein kinase Tec, ZINC ION 著者 Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Pederson, K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2012-06-15 公開日 2012-08-15 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of PH Domain of Tyrosine-protein kinase Tec from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR3504C To be Published
3SNH	Crystal structure of nucleotide-free human dynamin1 分子名称: Dynamin-1 著者 Faelber, K, Daumke, O. 登録日 2011-06-29 公開日 2011-09-21 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structure of nucleotide-free dynamin. Nature, 477, 2011
1NTY	Crystal structure of the first DH/PH domain of Trio to 1.7 A 分子名称: Triple functional domain protein 著者 Skowronek, K.R, Zheng, Y, Nassar, N. 登録日 2003-01-30 公開日 2004-06-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids. J.Biol.Chem., 279, 2004
3HK0	Crystal Structure of the RA and PH Domains of Grb10 分子名称: Growth factor receptor-bound protein 10, THIOCYANATE ION 著者 Hubbard, S.R, Depetris, R.S, Wu, J. 登録日 2009-05-22 公開日 2009-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14. Nat.Struct.Mol.Biol., 16, 2009
3HW2	Crystal structure of the SifA-SKIP(PH) complex 分子名称: Pleckstrin homology domain-containing family M member 2, Protein sifA 著者 Diacovich, L, Dumont, A, Lafitte, D, Soprano, E, Guilhon, A.-A, Bignon, C, Gorvel, J.-P, Bourne, Y, Meresse, S. 登録日 2009-06-17 公開日 2009-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Interaction between the SifA virulence factor and its host target skip is essential for salmonella pathogenesis J.Biol.Chem., 284, 2009
6TT2	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: MAGNESIUM ION, Tyrosine-protein kinase BTK, ZINC ION 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-23 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TSE	Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 1-methylindole-2,3-dione, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2019-12-20 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
6TUH	The PH domain of Bruton's tyrosine kinase mutant R28C 分子名称: 4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published
1QQG	CRYSTAL STRUCTURE OF THE PH-PTB TARGETING REGION OF IRS-1 分子名称: INSULIN RECEPTOR SUBSTRATE 1 著者 Dhe-Paganon, S, Shoelson, S.E. 登録日 1999-06-04 公開日 1999-08-01 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of the pleckstrin homology-phosphotyrosine binding (PH-PTB) targeting region of insulin receptor substrate 1. Proc.Natl.Acad.Sci.USA, 96, 1999
6U3E	Best fitting antiparallel model for Volume 1 of truncated dimeric Cytohesin-3 (Grp1; amino acids 14-399) 分子名称: Cytohesin-3, INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE 著者 Das, S, Lambright, D.G. 登録日 2019-08-21 公開日 2019-09-25 最終更新日 2023-11-29 実験手法 ELECTRON MICROSCOPY (53 Å) 主引用文献 Structural Organization and Dynamics of Homodimeric Cytohesin Family Arf GTPase Exchange Factors in Solution and on Membranes. Structure, 27, 2019
6TVN	Crystal Structure of 5-bromoindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase 分子名称: 5-bromanyl-1,3-dihydroindol-2-one, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... 著者 Brear, P, Wagstaff, J, Hyvonen, M. 登録日 2020-01-10 公開日 2020-11-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C To Be Published

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